Treatment for ischemic stroke: From thrombolysis to thrombectomy and remaining challenges [0.03%]
缺血性卒中的治疗：从溶栓到取栓及面临的挑战
Tiandong Leng,Zhi-Gang Xiong
Tiandong Leng
Stroke is a leading cause of death and long-term disabilities. Despite decades of extensive efforts in search of brain injury mechanisms and therapeutic interventions, pharmacological treatment is limited to the use of thrombolytic agent ti...
Bradley Kolb,Hamidreza Saber,Hassan Fadel et al.
Bradley Kolb et al.
Stroke is an important cause of morbidity and mortality worldwide. Development of novel neuroprotectants is of paramount importance. This review seeks to summarize the recent evidence for the role of the endocannabinoid signaling system in ...
Hypoxia-inducible factor-1 α and RIP3 triggers NLRP3 inflammasome in ischemic stroke [0.03%]
缺血性卒中中HIF-1α和RIP3启动NLRP3炎症小体的作用及机制研究
Qian Jiang,Christopher R Stone,Xiaokun Geng et al.
Qian Jiang et al.
Razaz Mageid,Yuchuan Ding,Paul Fu
Razaz Mageid
Emergency department visits for a headache are relatively common, and in most cases, the etiologies of the headache are typically benign. We present a case of a patient who presented to the emergency room for new onset of unremitting unilat...
Case Reports
Brain circulation. 2018 Oct-Dec;4(4):188-190. DOI:10.4103/bc.bc_34_18 2018
Retained Solitaire FR device after mechanical thrombectomy: Case review and management strategies [0.03%]
机械取栓术中Solitaire FR支架取留的处理策略及案例报告
Jay P Kinariwala,Gary B Rajah,Ali W Luqman
Jay P Kinariwala
Solitaire FR device is a Food and Drug Administration-approved device for mechanical thrombectomy. It has been tested in various clinical trials for its safety and efficacy. We report a case of inadvertent detachment of the Solitaire FR dev...
Case Reports
Brain circulation. 2018 Oct-Dec;4(4):185-187. DOI:10.4103/bc.bc_12_18 2018
Effects of three flavonoids from an ancient traditional Chinese medicine Radix puerariae on geriatric diseases [0.03%]
三种古传统中药地菍根黄酮对老年病的药效研究
Sijia Zhang,Jue Wang,Haiping Zhao et al.
Sijia Zhang et al.
As the worldwide population ages, the morbidity of neurodegenerative, cardiovascular, cerebrovascular, and endocrine diseases, such as diabetes and osteoporosis, continues to increase. The etiology of geriatric diseases is complex, involvin...
Brain-gut axis after stroke [0.03%]
卒中后的脑肠轴
Awadhesh K Arya,Bingren Hu
Awadhesh K Arya
Stroke leads to inflammatory and immune response in the brain and immune organs. The gut or gastrointestinal tract is a major immune organ equipped with the largest pool of immune cells representing more than 70% of the entire immune system...
Zi Wang,Yuchuan Ding,Paul Fu
Zi Wang
Stroke is a leading cause of disability in the United States and current treatment for stroke is limited to two modalities with well-defined time restraints. The prehospital setting is a significant and relatively easy setting for innovatio...
Marc Fisher,Yunyun Xiong
Marc Fisher
The treatment of acute ischemic stroke patients with a proximal large vessel occlusion (LVO) in the anterior circulation has seen tremendous advances initially with the demonstration of the substantial benefit of thrombectomy within 6-h of ...
Current progress in searching for clinically useful biomarkers of blood-brain barrier damage following cerebral ischemia [0.03%]
脑缺血后血脑屏障损害的临床应用价值生物标记物研究进展
Weili Li,Rong Pan,Zhifeng Qi et al.
Weili Li et al.
Ischemic stroke is a leading cause of death and disability. Fear of intracranial hemorrhage (ICH) has been the primary reason for withholding tissue plasminogen activator (tPA) and thrombectomy, the only two widely accepted treatments for i...