Radioenhancing Hafnium Oxide Nanoparticles (NBTXR3) Followed by Stereotactic Body Radiation Therapy in Patients With Hepatocellular Carcinoma and Liver Metastases (NBTXR3-103): Phase 1 Dose-Escalation Trial [0.03%]
一种新型放疗增敏剂——纳米颗粒(NBTXR3)配合立体定向体部放射治疗用于治疗原发性肝癌和肝脏转移瘤患者的I期临床试验：剂量递增试验
Enrique Chajon,Marc Pracht,Yan Rolland et al.
Enrique Chajon et al.
Purpose: Stereotactic body radiation therapy (SBRT) is a common treatment for unresectable liver cancers; however, delivering ablative doses while minimizing normal tissue toxicity is challenging. NBTXR3, a novel radioenh...
Boron Neutron Capture Therapy in Recurrent High-Grade Gliomas: Safety, Efficacy, and Pharmacokinetics From a Multicenter, Dose-Escalation Phase 1 Trial [0.03%]
复发性胶质肉瘤硼中子俘获治疗的安全性、有效性和药代动力学：多中心剂量递增I期临床试验结果
Woohyoung Kim,Jae-Sung Park,Jin-Ho Song et al.
Woohyoung Kim et al.
Purpose: Boron neutron capture therapy (BNCT) is an advanced radiation therapy delivering highly selective tumor cell destruction via localized fission reactions. This phase 1 study evaluated the safety and efficacy of BN...
Impact of Quality Improvement Interventions on the Efficiency of Treatment Planning Timelines in a Modern Proton Therapy Clinic [0.03%]
质量改善干预措施对现代质子治疗中心治疗计划效率的影响
Kristen A McConnell,Maria Valladares,Alonso N Gutierrez et al.
Kristen A McConnell et al.
Purpose: Following the guidance of The American Association of Physicists in Medicine (AAPM) Medical Physics Practice Guideline (MPPG) 4a/4b, AAPM Task Groups 100/275, and American Society for Radiation Oncology's Safety ...
Feasibility of Very High Cumulative Equivalent Dose in 2 Gy Fraction in Locally Advanced Central/Ultracentral Nonsmall Cell Lung Cancer Treated With Conventional Chemoradiation Therapy and a Stereotactic Boost [0.03%]
常规放化疗联合立体定向 boost 对局部晚期中央型/ ultracentral 非小细胞肺癌高剂量 (2 Gy 每分次) 累积生物有效剂量的可行性研究
Anna Gueiderikh,Baptiste Lhomel,Renaud Schiappa et al.
Anna Gueiderikh et al.
Purpose: This study aims to evaluate the cumulative equivalent dose in 2 Gy fractions (EQD2) to organs at risk and its potential correlation with toxicities in patients with locally advanced nonsmall cell lung cancer trea...
ChatGPT Versus DeepSeek: Assessing Artificial Intelligence Performance on Radiation Oncology Examination Questions [0.03%]
放射肿瘤学考试试题的人工智能性能评估：ChatGPT与DeepSeek的比较
Ronald Chow,Ajay Zheng,Chenxi Gao et al.
Ronald Chow et al.
Purpose: Large language models have been assessed for their ability to receive and answer medical questions. Recently, there has been a new large language model named DeepSeek released, which has not been assessed for med...
Lutetium 177Lu Vipivotide Tetraxetan Efficacy and Toxicity in Advanced Prostate Cancer [0.03%]
镥-177维皮沃替坦四氧代治疗晚期前列腺癌的疗效和毒性作用
Anthony Y Zhang,Helaine Bertsch,Ahmed Chaudhary et al.
Anthony Y Zhang et al.
Purpose: This retrospective study aimed to evaluate the efficacy and toxicity of lutetium 177Lu vipivotide tetraxetan ([LuVT], Pluvicto, Novatis Pharmaceutical Corporation), a peptide receptor radionuclide therapy, in met...
Impact of a Dedicated Inpatient Radiation Oncology Consult Service on Goal-Concordant Care [0.03%]
一个专用的放射肿瘤科住院咨询部门对目标一致护理的影响
Morgan E Freret,Divya Yerramilli,Victoria S Brennan et al.
Morgan E Freret et al.
Purpose: Radiation therapy has an increasing role in the management of metastatic cancers. Integrating radiation with surgical and systemic approaches is complex, and inappropriate management can lead to prolonged hospita...
Reduced-Dose Hypofractionated Radiation Therapy (3 Gy × 3 Fractions) for Indolent Non-Hodgkin's lymphoma (POSEIDON): A Multisite Phase 2 Randomized Trial Protocol [0.03%]
低剂量分次放射治疗（3Gy×3分次）用于惰性非霍奇金淋巴瘤（POSEIDON):多中心II期随机试验方案
Omran Saifi,Scott C Lester,William G Rule et al.
Omran Saifi et al.
Indolent non-Hodgkin's lymphoma, including follicular and marginal zone lymphoma, is highly radiosensitive, with radiation therapy (RT) serving as an effective treatment. Although standard RT doses (24 Gy in 12 fractions) provide excellent ...
Early Experience Comparing Reduced Planning Target Volume Margins Using Cone Beam Computed Tomography Scan Guided Online Adaptive Radiation Therapy to Nonadaptive, Traditional Margin Plans for Muscle-Invasive Bladder Cancer [0.03%]
在线自适应放射治疗膀胱肌肉浸润性癌的早期经验：应用锥形束CT扫描降低计划靶区体积边缘与传统边界计划非适应性放疗的对比研究
Samuel B Hayworth,Whitney S Hotsinpiller,Joel Pogue et al.
Samuel B Hayworth et al.
Purpose: Radiation therapy (RT) for muscle-invasive bladder cancer (MIBC) requires substantial planning target volume (PTV) margins to accommodate bladder-filling variability. We hypothesized that cone beam computed tomog...
Safety of Combining Radiation Therapy and Antibody Drug Conjugates in Advanced Urothelial and Other Cancers [0.03%]
放疗联合抗体偶联药物治疗晚期尿路上皮癌和其他肿瘤的安全性研究
Derrick Lock,Yash S Soni,Lindsay Hwang et al.
Derrick Lock et al.
Antibody drug conjugates (ADCs) such as enfortumab vedotin and sacituzumab govitecan are novel treatments increasingly used for metastatic urothelial carcinoma. There is limited data evaluating their safety when combined with radiation ther...