PEG-GNPs aggravate MCD-induced steatohepatitic injury and liver fibrosis in mice through excessive lipid accumulation-mediated hepatic inflammatory damage [0.03%]
聚乙二醇化金纳米颗粒通过介导肝脂质过度蓄积和炎症损伤加重小鼠MCD诱导的肝脂肪变性及纤维化病理进程
Hanqing Chen,Shuang Zhou,Wei Chen et al.
Hanqing Chen et al.
Rapid development of gold nanoparticles (GNPs) in delivering pharmaceutics and therapeutics approaches still linger the concerns of their toxic effects. Nonalcoholic steatohepatitis (NASH) is characterized by excessive lipid accumulation an...
Transferability and reproducibility of exposed air-liquid interface co-culture lung models [0.03%]
暴露的空气-液体界面共培养肺模型的可转移性和可重复性
Hedwig M Braakhuis,Eric R Gremmer,Anne Bannuscher et al.
Hedwig M Braakhuis et al.
Background: The establishment of reliable and robust in vitro models for hazard assessment, a prerequisite for moving away from animal testing, requires the evaluation of model transferability and reproducibility. Lung mo...
New insight into the biocompatibility/toxicity of graphene oxides and their reduced forms on Chlamydomonas reinhardtii [0.03%]
少甲壳藻对石墨烯及其衍生物的耐受性研究获得新进展
Zuzana Bytešníková,Martina Koláčková,Markéta Dobešová et al.
Zuzana Bytešníková et al.
Graphene oxides (GOs) and their reduced forms are often discussed both positively and negatively due to the lack of information about their chemistry and structure. This study utilized GOs with two sheet sizes that were further reduced by t...
Comprehensive analysis of common polymers using hyphenated TGA-FTIR-GC/MS and Raman spectroscopy towards a database for micro- and nanoplastics identification, characterization, and quantitation [0.03%]
基于TG-AFTIR-GC/MS和拉曼光谱的联用技术对常用聚合物进行全面分析，构建微塑料和纳米塑料的鉴别、表征及定量数据库
Sungyoon Jung,Achyut J Raghavendra,Anil K Patri
Sungyoon Jung
Environmental contamination by micro- and nanoplastics (MNPs) is well documented with potential for their increased accumulation globally. Growing public concern over environmental, ecological, and human exposure to MNPs has led to exponent...
Localisation and identification of polystyrene particles in tissue sections using Raman spectroscopic imaging [0.03%]
基于拉曼光谱成像的组织切片中聚苯乙烯颗粒的定位及识别
Jasmin Kniese,Sven Ritschar,Lina Bünger et al.
Jasmin Kniese et al.
The uptake of microplastic particles (MPP) by organisms is frequently described and poses a potential risk for these organisms and ultimately for humans either through direct uptake or trophic transfer. Currently, the in-situ detection of M...
Jiangxue Li,Liuxiang Wang,Shilin Li et al.
Jiangxue Li et al.
Nanomaterial have shown excellent properties in the food industry. Although iron oxides are often considered safe and widely used as food additives, the toxicity of nano‑iron oxide remains unclear. Here we established a subchronic exposure...
Graphene oxide exposure alters gut microbial community composition and metabolism in an in vitro human model [0.03%]
氧化石墨烯暴露于人体模型中会改变肠道微生物群组成和代谢
Sneha P Couvillion,Robert E Danczak,Xiaoqiong Cao et al.
Sneha P Couvillion et al.
Graphene oxide (GO) nanomaterials have unique physicochemical properties that make them highly promising for biomedical, environmental, and agricultural applications. There is growing interest in the use of GO and extensive in vitro and in ...
Long-term exposure of molybdenum disulfide nanosheets leads to hepatic lipid accumulation and atherogenesis in apolipoprotein E deficient mice [0.03%]
二硫化钼纳米片长期暴露可致阿波罗蛋白E基因敲除小鼠肝脂质蓄积和动脉粥样硬化病变形成
Ziyi Yan,Zixuan Liu,Bingwei Yang et al.
Ziyi Yan et al.
Before their large-scale applications, it is necessary to understand the biological effects of nanomaterials. Although two-dimensional nanomaterials (2D NMs) molybdenum disulfide nanosheets (MoS2 NSs) are promising in biomedical fields, the...
TRAAC framework to improve regulatory acceptance and wider usability of tools and methods for safe innovation and sustainability of manufactured nanomaterials [0.03%]
改进监管接受度和工具方法的广泛应用以实现纳米材料的安全创新和可持续性-TRAAC框架
Neeraj Shandilya,Marie-Sophie Barreau,Blanca Suarez-Merino et al.
Neeraj Shandilya et al.
There has been an increasing use of advanced materials, particularly manufactured nanomaterials, in industrial applications and consumer products in the last two decades. It has instigated concerns about the sustainability, in particular, r...
Effects of different sizes of polystyrene micro(nano)plastics on soil microbial communities [0.03%]
不同尺寸的聚苯乙烯微(纳米)塑料对土壤微生物群落的影响
Kwanyoung Ko,Haegeun Chung,Woong Kim et al.
Kwanyoung Ko et al.
Micro(nano)plastic (MNP) pollution in soil environments is a major concern, but the effects of different sizes of MNPs on soil microbial communities, which are crucial in nutrient cycling, has not been well investigated. In this study, we a...