Jared K Woods,Tahereh Ziafazeli,Blanka Rogina
Jared K Woods
BACKGROUND: Rpd3 is a conserved histone deacetylase that removes acetyl groups from lysine residues within histones and other proteins. Reduction or inhibition of Rpd3 extends longevity in yeast, worms, and flies. Previous studies in flies ...
Ratios of soluble and insoluble dietary fibers on satiety and energy intake in overweight pre- and postmenopausal women [0.03%]
可溶性和不可溶性膳食纤维的比例对体重超标的绝经期前后妇女的饱腹感和能量摄入的影响
Britt Burton-Freeman,Dhanesh Liyanage,Sajida Rahman et al.
Britt Burton-Freeman et al.
BACKGROUND: Fibers' properties impact different mechanisms involved in satiety and energy intake regulation and metabolic outcomes. OBJECTIVE: Evaluate the effect of fiber types and menopausal status on satiety and metabolic responses in ov...
Long-term calorie restriction in humans is not associated with indices of delayed immunologic aging: A descriptive study [0.03%]
长期的热量限制与延迟免疫老化无相关性：一项描述性研究
A Janet Tomiyama,Jeffrey M Milush,Jue Lin et al.
A Janet Tomiyama et al.
BACKGROUND: Delayed immunologic aging is purported to be a major mechanism through which calorie restriction (CR) exerts its anti-aging effects in non-human species. However, in non-obese humans, the effect of CR on the immune system has be...
MicroRNA 21 is up-regulated in adipose tissue of obese diabetic subjects [0.03%]
肥胖糖尿病患者脂肪组织中 MicroRNA 21 的表达上调
Valeria Guglielmi,Monica D&#x;Adamo,Rossella Menghini et al.
Valeria Guglielmi et al.
We investigated miR21 expression in omental (OAT) and subcutaneous adipose tissue (SAT) from 16 obese subjects undergoing bariatric surgery. Patients were divided into two age- and BMI-matched groups according to the presence of type 2 diab...
Dietary polyunsaturated fatty acids and their metabolites: Implications for diabetes pathophysiology, prevention, and treatment [0.03%]
多不饱和脂肪酸及其代谢产物对糖尿病病理生理、预防和治疗的影响
Joshua C Neuman,Rachel J Fenske,Michelle E Kimple
Joshua C Neuman
Sun Y Kim,Ashley E Webb
Sun Y Kim
The FOXO family of transcription factors plays a conserved role in longevity and tissue homeostasis across species. In the mammalian nervous system, emerging evidence has implicated FOXOs in cognitive performance, stem cell maintenance, reg...
Amol Chaudhari,Richa Gupta,Kuldeep Makwana et al.
Amol Chaudhari et al.
Diets and feeding regimens affect many physiological systems in the organism and may contribute to the development or prevention of various pathologies including cardiovascular diseases or metabolic syndromes. Some of the dietary paradigms,...
Diet-induced weight loss is sufficient to reduce senescent cell number in white adipose tissue of weight-cycled mice [0.03%]
饮食诱导的体重减轻足以减少周期性肥胖小鼠白色脂肪组织中衰老细胞的数量
Edward O List,Elizabeth Jensen,Jesse Kowalski et al.
Edward O List et al.
Previously, our laboratory reported that weight-cycled mice outlive their obese counterparts. To gain a better mechanistic understanding of these results, we evaluated cellular senescence in white adipose tissue (WAT) of lean, obese, and we...
High-flavonoid intake induces cognitive improvements linked to changes in serum brain-derived neurotrophic factor: Two randomised, controlled trials [0.03%]
高黄酮摄入通过改变血清脑源性神经营养因子水平诱导认知改善：两项随机对照试验
Sara Neshatdoust,Caroline Saunders,Sophie M Castle et al.
Sara Neshatdoust et al.
BACKGROUND: Recent clinical studies have indicated the beneficial impact of dietary flavonoid intake on human cognitive performance. Although the mechanisms that mediate such improvements are currently unclear, animal and human trial data s...
Dietary olive oil induces cannabinoid CB2 receptor expression in adipose tissue of ApcMin/+ transgenic mice [0.03%]
膳食橄榄油可诱导ApcMin/+转基因小鼠脂肪组织的大麻素CB2受体的表达
Maria Notarnicola,Valeria Tutino,Angela Tafaro et al.
Maria Notarnicola et al.
BACKGROUND: Cannabinoid- 2 (CB2) receptor is known for its anti-obesity effects silencing the activated immune cells that are key drivers of metabolic syndrome and inflammation. Nutritional interventions in experimental models of carcinogen...