Bioorthogonal chemistry: Bridging chemistry, biology, and medicine [0.03%]
化学生物学中的仿生化学：连接化学、生物与医学的新纽带
Kaitlin M Hartung,Ellen M Sletten
Kaitlin M Hartung
As chemical biologists sought methods to modify and study biomolecules in their native environments, the need for bioorthogonal chemical reactions emerged. These fast and selective reactions between otherwise inert, abiotic functional group...
Genetically Enabling Phosphorus Fluoride Exchange Click Chemistry in Proteins [0.03%]
蛋白质中磷氟交换点击化学的遗传学启用
Li Cao,Bingchen Yu,Shanshan Li et al.
Li Cao et al.
Phosphorus Fluoride Exchange (PFEx), recently debuted in small molecules, represents the forefront of click chemistry. To explore PFEx's potential in biological settings, we developed amino acids PFY and PFK featuring phosphoramidofluoridat...
Opportunities for Insight into the Mechanism of Efficient CO2/CO Interconversion at a Nickel-Iron Cluster in CO Dehydrogenase [0.03%]
镍铁簇在二氧化碳/一氧化碳互变高效酶催化中的作用机制研究机遇
Samuel H Newman-Stonebraker,Theodore J Gerard,Patrick L Holland
Samuel H Newman-Stonebraker
The reduction of CO2 with low overpotential and high selectivity is a crucial challenge in catalysis. Fortunately, natural systems have evolved enzymes that achieve this catalytic reaction very efficiently at a complex nickel-iron-sulfur cl...
Poison to Promise: The Resurgence of Organophosphorus Fluoride Chemistry [0.03%]
从毒药到承诺： organophosphorus-氟化学的复苏
William P Chappell,Natalie Schur,James A Vogel et al.
William P Chappell et al.
Organophosphorus(V) fluorides have a long and tumultuous history, with early applications as toxins and nerve agents reflecting their poisonous past. Behind these very real safety considerations, there is also growing potential in a wide ra...
Erratum: Influence of structural moieties in squaraine dyes on optoacoustic signal shape and intensity [0.03%]
erratum：紫日花染料的结构单元对其光声信号形状和强度的影响
William M MacCuaig,Carly Wickizer,Richard S Van et al.
William M MacCuaig et al.
[This corrects the article PMC11087056.].
Published Erratum
Chem. 2024 Jun 13;10(6):1950-1951. DOI:10.1016/j.chempr.2024.05.019 2024
Adam D Moorhouse,Joshua A Homer,John E Moses
Adam D Moorhouse
The impact of click chemistry was recently recognized with the 2022 Nobel Prize in Chemistry. The breadth of areas where click chemistry has accelerated discovery is prodigal. In one of the most written about subjects in chemistry over rece...
Phosphorus fluoride exchange: Multidimensional catalytic click chemistry from phosphorus connective hubs [0.03%]
磷氟交换：源自磷连接中心的多维度催化点击化学
Shoujun Sun,Joshua A Homer,Christopher J Smedley et al.
Shoujun Sun et al.
Phosphorus Fluoride Exchange (PFEx) represents a cutting-edge advancement in catalytic click-reaction technology. Drawing inspiration from Nature's phosphate connectors, PFEx facilitates the reliable coupling of P(V)-F loaded hubs with aryl...
Jeffrey Gorman,Stephanie M Hart,Torsten John et al.
Jeffrey Gorman et al.
Natural light-harvesting systems spatially organize densely packed dyes in different configurations to either transport excitons or convert them into charge photoproducts, with high efficiency. In contrast, artificial photosystems like orga...
A prebiotic Krebs cycle analog generates amino acids with H2 and NH3 over nickel [0.03%]
镍催化H2和NH3在预生物Krebs循环类反应中合成氨基酸
Harpreet Kaur,Sophia A Rauscher,Emilie Werner et al.
Harpreet Kaur et al.
Hydrogen (H2) has powered microbial metabolism for roughly 4 billion years. The recent discovery that it also fuels geochemical analogs of the most ancient biological carbon fixation pathway sheds light on the origin of metabolism. However,...
Erratum: Influence of structural moieties in squaraine dyes on optoacoustic signal shape and intensity [0.03%]
erratum：squaraine 染料的结构基团对其光电声信号形状和强度的影响
William M MacCuaig,Carly Wickizer,Richard S Van et al.
William M MacCuaig et al.
[This corrects the article PMC11087056.].
Published Erratum
Chem. 2024 Feb 8;10(2):746. DOI:10.1016/j.chempr.2024.01.008 2024