Non-AIDS-defining malignancies in Japanese hemophiliacs with HIV-1 infection [0.03%]
日本HIV-1感染血友病患者中非艾滋病定义性恶性肿瘤的发生率
Shinichi Oka,Mikiko Ogata,Misao Takano et al.
Shinichi Oka et al.
Along improvement of prognosis of HIV-1-infected patients due to successful anti-retroviral therapy, main causes of death in the patients have been changing from AIDS to non-AIDS defining malignancies (NADM) recently. However, little is kno...
A novel HIV-1 protease inhibitor, GRL-044, has potent activity against various HIV-1s with an extremely high genetic barrier to the emergence of HIV-1 drug resistance [0.03%]
一种新型HIV-1蛋白酶抑制剂GRL-044对各种HIV-1具有极高的遗传屏障以产生抗药性病毒株的优异活性
Manabu Aoki,Simon B Chang,Debananda Das et al.
Manabu Aoki et al.
We designed, synthesized, and identified two novel nonpeptidic HIV-1 protease inhibitors (PIs), GRL- 037 and GRL-044, containing P2-tetrahydropyrano-tetrahydrofuran (Tp-THF), P1-benzene and P1-methoxybenzene, respectively, and P2'-isopropyl...
Hidekatsu Yanai,Yuji Hirowatari,Hiroshi Yoshida
Hidekatsu Yanai
Diabetes is one of the well-established independent risk factors for cardiovascular diseases. Diabetes induces dyslipidemia which is characterized by elevated fasting triglyceride (TG) and reduced high-density lipoprotein-cholesterol (HDL-C...
Hepatocellular carcinoma with non-B and non-C hepatitis origin: epidemiology in Japan and surgical outcome [0.03%]
非乙型及丙型肝炎引起的肝细胞癌的流行病学和外科治疗结果(日本)
Norihiro Kokudo,Nobuyuki Takemura,Tatsuya Kanto et al.
Norihiro Kokudo et al.
During the last two decades, there has been a dramatic increase in so-called non-B non-C hepatocellular carcinoma (NBNC HCC) in Japan. Majority of NBNC HCC are considered as so-called metabolic HCC and some could be related to occult HBV in...
Efficient and practical dissemination of information on viral hepatitis in Japan: an effort by the Hepatitis Information Center, National Center for Global Health and Medicine [0.03%]
日本肝炎信息中心关于高效实用传播病毒性肝炎知识的努力：国立全球卫生与医学研究中心的经验报告
Yuko Kitayama,Masaaki Korenaga,Hiroko Setoyama et al.
Yuko Kitayama et al.
One of the important missions of the Hepatitis Information Center is to disseminate information regarding liver disease. The Hepatitis Information Center, National Center for Global Health and Medicine (NCGM) has been endeavoring to ensure ...
Qi Tang,Hongzhou Lu
Qi Tang
Based on data from the Chinese Center for Disease Control and Prevention (CDC), there were a total of 861,042 people with human immunodeficiency virus (HIV)/ immune deficiency syndrome (AIDS) as of December 31, 2018 in China, a total of 148...
Hidechika Akashi,Aya Ishizuka,Sangnim Lee et al.
Hidechika Akashi et al.
The Meetings of Health Ministers of the Group of Twenty (G20) that started at the G20 Summit in Berlin, Germany in 2017 have provided a platform for the discussion of global health matters such as antimicrobial resistance (AMR), public heal...
Population aging in Japan: policy transformation, sustainable development goals, universal health coverage, and social determinates of health [0.03%]
日本的人口老龄化问题：政策转型与可持续发展目标、全民健康覆盖和社会健康决定因素的关系研究
Hiroki Nakatani
Hiroki Nakatani
Japan is aging rapidly, and its society is changing. Population aging and social change are mutually linked and appear to form a vicious cycle. Post-war Japan started to invest intensively in infectious disease control by expanding health s...
Hiroaki Mitsuya,Norihiro Kokudo
Hiroaki Mitsuya
Focusing on the theme of global health and medicine, at the beginning of the new era (Reiwa) in Japan, we are pleased and honored to launch Global Health & Medicine, an international, open-access, peer-reviewed journal, published by the Nat...