Global health systems research symposium in Nagasaki, Japan:Building momentum for health systems strengthening andcommitment to core values of global health amid headwinds [0.03%]
日本长崎全球卫生体系研究大会：在全球逆风中加强卫生系统建设并致力于全球卫生核心价值的承诺
Hitoshi Murakami,Kiyoshi Kita,Ikuo Takizawa et al.
Hitoshi Murakami et al.
Since 2025, in addition to financing, the core values of global health-including community engagement, equity, evidence-informed practices, and multilateral collaboration-have been challenged by powerful global leaders. The 8th Global Sympo...
Current status and challenges of peer support for young people whoengage in over-the-counter medicine overdose in Japan: Practice-orientedperspectives [0.03%]
日本非处方药过量服用青年的同伴支持现状与挑战：实践视角
Masana Ujihara,Atsushi Iwasawa
Masana Ujihara
Over-the-counter (OTC) medicine overdose among adolescents and young adults is an increasingly visible concern in Japan, intersecting with suicide prevention priorities and unmet psychosocial needs. In this article, we share frontline persp...
Regional and facility-type variations in infectious diseases in childcare and early childhood education facilities in Japan during the COVID-19 pandemic: A nationwide cross-sectional questionnaire survey [0.03%]
日本新冠疫情下的儿童护理和学前教育机构传染病区域和设施类型差异：全国横断面问卷调查
Akiko Uno,Sonomi Nakajima
Akiko Uno
Young children are susceptible to infectious diseases due to their developing immune systems and close contact in group care settings. During the coronavirus disease 2019 (COVID-19) pandemic, infection prevention measures may have altered t...
Japan's high-quality healthcare system despite physician shortages: Exploring the paradox and pathways toward sustainable healthcare [0.03%]
日本医疗人才短缺下的高品质医疗体系——探析现状及可持续发展路径
Machiko Uenishi,Peipei Song,Takashi Karako
Machiko Uenishi
Japan's rapidly aging population presents significant demographic pressures, and yet the country maintains high standards of healthcare delivery with remarkably low rates of preventable and treatable mortality. According to the latest data ...
AI in clinical trials: Current status, challenges, and future directions for emergency infectious disease clinical trials -Insights from the 2025 iCROWN Symposium [0.03%]
人工智能在临床试验中的应用：紧急传染病临床试验的现状、挑战和未来方向——来自2025年iCROWN研讨会的见解
Eriko Morino,Daisuke Tokita
Eriko Morino
Artificial intelligence (AI) has the potential to transform how drug development and clinical trials are conducted. The 2025 Infectious Disease Clinical Research Network with National Repository (iCROWN) Symposium held in Japan on January 2...
Regional health security architecture in ASEAN countries: Lessons from regional CDC models and Japan's strategic partnership for ACPHEED development [0.03%]
东盟国家的区域卫生安全架构：区域cdc模式和日本战略伙伴关系支持ACPHEED发展的启示
Shinsuke Miyano,Ikuma Nozaki,Masahiko Hachiya et al.
Shinsuke Miyano et al.
The COVID-19 pandemic exposed critical gaps in regional health security mechanisms, prompting ASEAN to establish the ASEAN Centre for Public Health Emergencies and Emerging Diseases (ACPHEED), with functions distributed across Indonesia, Th...
Latent classes of frailty and their association with intrinsic capacity inolder cancer survivors: A study under the healthy aging paradigm [0.03%]
老年癌症幸存者的潜在脆弱性亚类及其与内在能力的关系：基于健康老龄化理念的研究
Hui Wang,Yan Kong,Yuxia Wu et al.
Hui Wang et al.
The aim of this study was to identify frailty profiles using latent class analysis (LCA) and examine their associations with intrinsic capacity (IC) among Chinese elderly cancer survivors. A total of 308 elderly cancer survivors were recrui...
Investigating the link between Japanese Anticholinergic Risk Scale and laxative prescription in older adults: A cross-sectional study of 9,838 patients using dispensing claims from community pharmacies [0.03%]
基于社区药房处方记录的9838名患者横断面研究：调查日本抗胆碱能风险量表与缓泻剂处方之间的联系
Wataru Takahashi,Yusuke Takahashi,Hiroyuki Tanaka et al.
Wataru Takahashi et al.
Anticholinergic medications can cause constipation in older adults. The Japanese Anticholinergic Risk Scale (JARS), released in May 2024, is not yet sufficiently validated clinically. We examined the association between total anticholinergi...
Prognostic comparison between osteoblastic and osteolytic metastases in prostate cancer [0.03%]
骨质形成性前列腺癌转移与骨质破坏性前列腺癌转移的预后比较
Akihiro Ono,Kazuki Akiyama,Ryohei Nishimoto et al.
Akihiro Ono et al.
Over 80% of patients develop bone metastases in the advanced stages of prostate cancer, resulting in a poor prognosis. To date, no study has explored the relationship between the type of bone metastasis and patient outcomes. The objective o...
Retrospective observational analysis of prasugrel dosage afterpercutaneous coronary intervention using the Clinical Deep DataAccumulation System database [0.03%]
应用临床深度数据积累系统数据库分析经皮冠状动脉介入术后普拉格雷剂量的回顾性观察研究
Yukio Hiroi,Yosuke Shimizu,Yukari Uemura et al.
Yukio Hiroi et al.
Prasugrel reduces the recurrence of atherosclerotic cardiovascular disease and restenosis after percutaneous coronary intervention (PCI). However, its actual dosage in Japan has not been well studied. This study aimed to compare different p...