Secondary Analysis of Randomized Controlled Trials: Methodological Considerations and Best Practices [0.03%]
随机对照试验二次分析的方法学考量与最佳实践
Qingyao Shang,Shuna Yao,Meishuo Ouyang et al.
Qingyao Shang et al.
Secondary analyses of randomized controlled trials (RCTs) offer an efficient way to maximize the value of existing trial data and explore clinical questions beyond the original trial scope. This review outlines methodological considerations...
Postpartum haemorrhage in pregnant carriers of haemophilia and women with von Willebrand disease: a nationwide inpatient database study [0.03%]
血友病怀孕携带者和血管性假血友病产妇产后出血：来自全国住院病人数据库的一项研究
Risa Ishida,Yusuke Sasabuchi,Kaori Koga et al.
Risa Ishida et al.
Background: Postpartum haemorrhage (PPH) is a major cause of maternal mortality worldwide. Previous studies have presented varying conclusions regarding the PPH risk in pregnant haemophilia carriers or women with von Will...
Association of age-appropriate vaccination status at 24 months with all-cause hospitalizations: A retrospective cohort study [0.03%]
24个月龄儿童按期接种状态与全因住院率的关联：一项回顾性队列研究
Wakana Maki,Shotaro Aso,Sachiko Ono et al.
Wakana Maki et al.
Background: Childhood vaccinations can be effective for preventing not only infectious diseases but also other diseases and traumas. This is because vaccines may have nonspecific immunological effects. Additionally, visit...
Development of a Otologic Surgery Registry Using Hearing Threshold Data Linked to Medical Record Database in Japan: A Preliminary Study [0.03%]
基于日本听力阈值的耳显微手术登记系统的初步研究及应用
Takashi Fujiwara,Kensuke Uraguchi
Takashi Fujiwara
Background: Routinely collected medical data, such as electronic medical records (EMRs) and medical claims, are necessary for developing disease registries. This study aimed to develop an otologic surgery registry by inte...
Japan Intensive Care Consortium: Nationwide Effort for Extracorporeal Membrane Oxygenation Care Optimization and Excellence Study: Study Protocol [0.03%]
日本重症监护联盟：体外膜氧合护理优化和卓越的全国性研究：研究方案
Daisuke Kasugai,Ryohei Yamamoto,Hirotada Kobayashi et al.
Daisuke Kasugai et al.
Background: Extracorporeal membrane oxygenation (ECMO) is a vital intervention in patients with severe cardiogenic shock or respiratory failure who are unresponsive to conventional therapies. Despite advances in ECMO tech...
Yohei Hashimoto,Hideo Yasunaga
Yohei Hashimoto
Propensity score (PS) is the probability of the exposure being assigned, conditional on the observed baseline covariates. Many observational studies have used PS analyses to investigate the effects of exposure on outcomes. This report revie...
Risk factors for nephropathy in individuals with new-onset type 2 diabetes undergoing treatment for hypertension: A retrospective analysis using the Diagnosis Procedure Combination database [0.03%]
日本初发型2型糖尿病伴高血压患者接受降压治疗后发生肾病的危险因素：基于诊断过程组合数据库的回顾性分析
Tomoko Ishigaki Suzuki,Mari Saito Oba,Kohei Uemura
Tomoko Ishigaki Suzuki
Background: Diabetic nephropathy is a common complication of diabetes. We investigated the risk factors for diabetic nephropathy in individuals newly diagnosed with type 2 diabetes. ...
Changes in the Use of Telephone Follow-ups among Patients with Urologic Malignancies in Japan [0.03%]
日本泌尿系统恶性肿瘤患者的电话随访使用变化
Keiko Fujino,Naoya Masumori,Shiro Hinotsu
Keiko Fujino
Background: This study aimed to compare telephone follow-ups for patients with urologic malignancies in Japan before and during the COVID-19 pandemic. Met...
Designing Single-Arm Clinical Trials: Principles, Applications, and Methodological Considerations [0.03%]
单臂临床试验的设计：原则、应用和方法学考虑因素
Shuna Yao,Qingyao Shang,Meishuo Ouyang et al.
Shuna Yao et al.
Single-arm trials (SATs) are clinical studies without a parallel control group, serving as a vital alternative to randomized controlled trials (RCTs) in scenarios where traditional trial designs are impractical. These trials are particularl...
Adverse events, including fractures, among older patients receiving mirogabalin versus pregabalin: A retrospective cohort study using a large claims database in Japan [0.03%]
日本大型索赔数据库的回顾性队列研究：与普瑞巴林相比，米罗加滨治疗老年患者的不良事件（包括骨折）
Kanako Makito,Akira Okada,Hideo Yasunaga
Kanako Makito
Background: Mirogabalin has a mechanism similar to that of pregabalin in the treatment of neuropathic pain. However, it remains unclear whether these drugs differ in terms of serious side effects, such as fall-related fra...