[Monoclonal antibodies to hemagglutinin of influenza b viruses victoria evolutionary lineage] [0.03%]
抗维多利亚株系流感病毒血凝素的单克隆抗体
E V Sorokin,T R Tsareva,A I Zheltukhina
E V Sorokin
Co-circulation of two evolutionary distinct lineages of influenza virus in one epidemic season has led to development specifc reagents for rapid identifcation and typing of new isolates. Panel of MAbs to hemagglutinin of influenza virus B/Brisb...
T I Glotova,O V Semenova,A A Nikonova et al.
T I Glotova et al.
The results of the study of the distribution of calicivirus infection in a population of domestic cats of different breeds, contained individually or the group method, the virus isolation in the cell culture and a comparative phylogenetic a...
[Mesenchymal stem cells enhance immune response and protect mice against lethal herpes viral infection] [0.03%]
骨髓间充质干细胞增强免疫反应并保护小鼠免受致死性疱疹病毒感染
R R Klimova,Е D Momotyuk,N A Demidova et al.
R R Klimova et al.
The objective of this study was to evaluate immunoregulatory and protective potential of mesenchymal stem cells (MSC) in a mouse model of lethal HSV1 infection. MSC were isolated from bone marrow of DBA mice and cultured in flasks with DMEM c...
[Modern ethiotropic chemotherapy of human cytomegalovirus infection: clinical effectiveness, molecular mechanism of action, drug resistance, new trends and prospects. Part 2] [0.03%]
[人巨细胞病毒感染的现代特效化疗:临床疗效、作用分子机制、抗药性、新趋势和前景(第二部分)]
V L Andronova
V L Andronova
A number of synthetic compounds, such as the nucleoside analog ganciclovir, its L-valine ester (a metabolic precursor of ganciclovir) and pyrophosphate analog foscarnet, are permitted for the treatment of HCMVrelated diseases in the WHO Eur...
[The use of monoclonal antibodies for the treatment of Ebola virus disease] [0.03%]
单克隆抗体治疗埃博拉病毒感染的研究进展及挑战
T E Sizikova,G V Borisevich,D V Shcheblyakov et al.
T E Sizikova et al.
Some drugs candidates for treatment of Ebola virus disease (EVD), have been studied, monoclonal antibody (mAb) cocktails have shown great potential as EVD therapeutics. The advantages of mAb therapy include low toxicity, high specifcity and...
[Etiological structure of influenza and other ARVI in St. Petersburg during epidemic seasons 2012-2016] [0.03%]
[2012-2016年圣彼得堡流感和其他ARI的病因结构]
M M Pisareva,V A Eder,Zh V Buzitskaya et al.
M M Pisareva et al.
The etiological structure of influenza and other acute respiratory viral infections including their rate of incidence in St. Petersburg and Leningrad region during 4 epidemic seasons has been studied. Seasonality of some respiratory viruses...
[Molecular and biological characteristics of vaccinary ERA-CB 20M of rabies virus] [0.03%]
狂犬病病毒疫苗株ERA-CB 20M的分子与生物学特性研究
M A Losich,O N Zaykova,I V Nepoklonova et al.
M A Losich et al.
The molecular and biological characteristics of the vaccine against rabies virus strain ERA-CB 20M obtained by the Russian rabiologist, doctor of medical sciences S.V. Gribencha by adapting and cloning the strain ERA and SAD in a transplant...
D G Maldov,V L Andronova,S S Grigorian et al.
D G Maldov et al.
Increased protease activity and a significant amount of granzyme B were observed in in organs of mice infected with acute herpes simplex virus HSV-1 with the introduction of Stimforte (100 or 250 µg/mouse). Thus, this drug activates killer...
[The experience in the application of nikavir in the schemes of perinatal chemoprophylactics of HIV infection: evaluation of the immunological and virusological effectiveness] [0.03%]
奈卡韦应用于预防HIV感染的围产期化学预防方案中的效果评价:免疫学和病毒学有效性的评估
E S Ivanova,N N Vorobeva,V S Sheludko
E S Ivanova
Objectives: The goal of this work was to study the immunological and virological efficacy of the domestic antiretroviral drug nicavir (at the optimal dose, as proven by previous clinical studies) with lamivudine, in compa...
[Modern ethiotropic chemotherapy of human cytomegalovirus infection: clinical effectiveness, molecular mechanism of action, drug resistance, new trends and prospects. Part 1] [0.03%]
[人巨细胞病毒感染的现代靶向化疗:临床疗效、分子作用机制、药物耐药性、新趋势和前景(第一部分)]
V L Andronova
V L Andronova
Modern chemotherapy of cytomegalovirus (CMV) infections has a very limited arsenal of first-line drugs. These are preparations of ganciclovir (GCV) belonging to the class of modified nucleosides and its metabolic precursor ganciclovir valin...