Changes in human papillomavirus genotypes associated with cervical intraepithelial neoplasia grade 2 lesions in a cohort of young women (2013-2016) [0.03%]
2013年至2016年间年轻女性宫颈上皮内瘤变Ⅱ级的人乳头瘤病毒感染分型变化趋势研究
Carrie R Innes,Peter H Sykes,Dianne Harker et al.
Carrie R Innes et al.
In 2008, a quadrivalent human papillomavirus (HPV) vaccine (genotypes 6, 11, 16, 18) became available in New Zealand. This study investigated whether the proportion of cervical intraepithelial neoplasia grade 2 (CIN2) lesions associated wit...
Vaccine programme stakeholder perspectives on a hypothetical single-dose human papillomavirus (HPV) vaccine schedule in low and middle-income countries [0.03%]
低收入和中等收入国家 HPV 疫苗接种项目利益攸关方对单剂次人乳头瘤病毒疫苗接种方案的看法
Katherine E Gallagher,Helen Kelly,Naomi Cocks et al.
Katherine E Gallagher et al.
Background: The World Health Organization (WHO) recommends a 2-dose HPV vaccine schedule for girls aged 9-14 years. As randomised controlled trials assessing the immunogenicity and efficacy of a 1-dose schedule are ongoin...
Human papillomavirus genotype and prognosis of cervical cancer: Favorable survival of patients with HPV16-positive tumors [0.03%]
人乳头瘤病毒基因型与宫颈癌预后的关系：HPV16阳性肿瘤患者的生存优势
Mamiko Onuki,Koji Matsumoto,Yuri Tenjimbayashi et al.
Mamiko Onuki et al.
The prognostic impact of human papillomavirus (HPV) type on invasive cervical cancer (ICC) was analyzed for 137 women treated for ICC at a single institution between 1999 and 2007. The study subjects were divided into three groups according...
Development and interlaboratory agreement of real-time PCR for HPV16 quantification in liquid-based cervical samples [0.03%]
液基细胞学样本中HPV16核酸定量检测体系的建立及多中心实验评估
David Guenat,Véronique Dalstein,Frédéric Mauny et al.
David Guenat et al.
High risk HPV infection is the necessary cause for the development of precancerous and cancerous lesions of the cervix. Among HPV, HPV16 represents the most carcinogenic type. Since the determination of HPV16 DNA load could be clinically us...
Long-term survival and swallowing outcomes in advanced stage oropharyngeal squamous cell carcinomas [0.03%]
晚期咽部鳞状细胞癌的长期生存率和吞咽功能结局
Jessica M Clark,Emma M Holmes,Daniel A O&#x;Connell et al.
Jessica M Clark et al.
Background: There is a paucity of studies reporting long-term survival outcomes for HPV/p16 positive oropharyngeal squamous cell carcinoma (OPSCC). This study aims to compare long-term outcomes of advanced stage p16 posit...
Oncogenic human papillomavirus infection and genotypes characterization among sexually active women in Tenkodogo at Burkina Faso, West Africa [0.03%]
博茨瓦纳特科多戈地区性活跃妇女的致癌人乳头瘤病毒感染及基因型特征化研究
Rogomenoma Alice Ouedraogo,Théodora Mahoukèdè Zohoncon,Sindimalgdé Patricia Guigma et al.
Rogomenoma Alice Ouedraogo et al.
Objective: This study was conducted to determine the prevalence and distribution of high-risk human papillomavirus (HR-HPV) genotypes among sexually active women in Tenkodogo, Burkina Faso. ...
Anogenital human papillomavirus virus DNA and sustained response to the quadrivalent HPV vaccine in women living with HIV-1 [0.03%]
人乳头瘤病毒DNA和四价HPV疫苗对HIV-1感染妇女的持续反应
Michelle S Cespedes,Minhee Kang,Erna Milunka Kojic et al.
Michelle S Cespedes et al.
Objectives: People living with HIV have increased Human Papillomavirus (HPV) related lesions and malignancies. We describe HPV DNA recovered from the cervix and anal canal, explore the effect of vaccination on HPV detecti...
Variants in immune-related genes and genital HPV 16 persistence in men [0.03%]
与免疫相关基因变异和男性HPV16持续感染的关系研究
Bigyan Mainali,Matthew B Schabath,Staci L Sudenga et al.
Bigyan Mainali et al.
Objectives: While most human papillomavirus (HPV) infection clears on its own, persistent HPV infection can cause genital warts and anal, penile and oropharyngeal cancers in men. We conducted genetic analysis in a sub-coh...
HPV E6 oncoproteins and nucleic acids in neck lymph node fine needle aspirates and oral samples from patients with oropharyngeal squamous cell carcinoma [0.03%]
口腔肿瘤患者的颈部淋巴结和口腔样品中的hpv e6癌蛋白及核酸检测
M Chernesky,D Jang,J Schweizer et al.
M Chernesky et al.
Commercial assays measuring HPV E6 viral oncoproteins, E6/E7 mRNA or DNA were used to test neck lymph node fine needle aspirates (FNA) and oropharyngeal samples (saliva and oral swabs) from 59 Canadian patients with oropharyngeal squamous c...
Murine HPV16 E7-expressing transgenic skin effectively emulates the cellular and molecular features of human high-grade squamous intraepithelial lesions [0.03%]
小鼠HPV16E7转基因皮肤可有效模拟人类高级别鳞状上皮内病变的细胞和分子特征
Z K Tuong,K Noske,P Kuo et al.
Z K Tuong et al.
Currently available vaccines prevent HPV infection and development of HPV-associated malignancies, but do not cure existing HPV infections and dysplastic lesions. Persistence of infection(s) in immunocompetent patients may reflect induction...