Characterization of a spray-dried candidate HPV L2-VLP vaccine stored for multiple years at room temperature [0.03%]
表征在室温下多年储存的喷雾干燥型候选HPV L2原病毒样颗粒疫苗的特性
Julianne Peabody,Pavan Muttil,Bryce Chackerian et al.
Julianne Peabody et al.
HPV infections are associated with human cancers. Although three prophylactic vaccines have been approved to protect against HPV infections, the vaccines require cold-chain storage and may not be suitable for third world countries with less...
Squamous intraepithelial lesions of the anal squamocolumnar junction: Histopathological classification and HPV genotyping [0.03%]
肛管鳞柱状上皮交界处的鳞状上皮内病变：病理分类和HPV基因型检测
Omar Clavero,Jenny McCloskey,Vicente Marco Molina et al.
Omar Clavero et al.
Background: Human papillomavirus (HPV)-related anal cancer lesions are often found adjacent to the squamocolumnar junction (SCJ). We have assessed the histopathology and associated HPV genotypes in anal SCJ lesions in sur...
Impact of baseline covariates on the immunogenicity of the 9-valent HPV vaccine - A combined analysis of five phase III clinical trials [0.03%]
基线协变量对九价人乳头瘤病毒疫苗免疫原性影响的合并分析——五项三期临床试验结果
Lone K Petersen,Jaime Restrepo,Edson D Moreira Jr et al.
Lone K Petersen et al.
Background: The immunogenicity profile of the 9-valent HPV (9vHPV) vaccine was evaluated across five phase III clinical studies conducted in girls and boys 9-15 years of age and young women 16-26 years of age. The effect ...
Increased TNF-alpha and sTNFR2 levels are associated with high-grade anal squamous intraepithelial lesions in HIV-positive patients with low CD4 level [0.03%]
肿瘤坏死因子α和可溶性TNFR2水平升高与HIV阳性低CD4计数患者的高级别肛门鳞状上皮内病变相关
Takeshi Haga,Jimmy T Efird,Sharof Tugizov et al.
Takeshi Haga et al.
Compared with HIV-negative individuals, HIV-positive individuals have a higher prevalence of anogenital human papillomavirus (HPV) infection, the causative agent of anogenital cancer. TNF-alpha is a major proinflammatory cytokine. sTNFR2 is...
Human papillomavirus (HPV) in young women in Britain: Population-based evidence of the effectiveness of the bivalent immunisation programme and burden of quadrivalent and 9-valent vaccine types [0.03%]
人乳头瘤病毒（HPV）与英国年轻女性：二价免疫程序的有效性以及四价和九价疫苗型负荷的基于人口的证据
Clare Tanton,David Mesher,Simon Beddows et al.
Clare Tanton et al.
Background: In 2008, the UK introduced an HPV immunisation programme in girls. Population-based prevalence estimates of bivalent (HPV-16/18), quadrivalent (HPV-6/11/16/18) and 9-valent (HPV-6/11/16/18/31/33/45/52/58) vacc...
A rare case of anal carcinosarcoma with human papilloma virus infection in both biphasic tumor elements: An immunohistochemical, molecular and ultrastructural study [0.03%]
双相肿瘤成分均感染人类乳头瘤病毒的罕见肛管癌肉瘤病例：一项免疫组化、分子及超微结构研究
Richard A Hickman,Azore-Dee Bradshaw,Nicholas Cassai et al.
Richard A Hickman et al.
Carcinosarcoma of the anus is rare and has yet to be reportedly associated with the keratinocyte-specific Human Papilloma Virus (HPV). We describe a case of anal carcinosarcoma with HPV infection in both the epithelial and mesenchymal compo...
HPV SEROSTATUS PRE- AND POST-VACCINATION IN A RANDOMIZED PHASE II PREPAREDNESS TRIAL AMONG YOUNG WESTERN CAPE, SOUTH AFRICAN WOMEN: THE EVRI TRIAL [0.03%]
南非西开普年轻女性 HPV 血清学状况的疫苗前期和后期研究：EVRI 研究
Staci L Sudenga,B Nelson Torres,Matthys H Botha et al.
Staci L Sudenga et al.
Background: HPV antibodies are a marker of past exposure to the virus. Our objective was to assess HPV serostatus pre- and post-vaccination among HIV-negative women. ...
HPV16 E6 seropositivity among cancer-free men with oral, anal or genital HPV16 infection [0.03%]
口腔、肛门或生殖器人乳头瘤病毒16型感染的无癌症男性中的HPV16 E6血清阳性率
Daniel C Beachler,Tim Waterboer,Christine M Pierce Campbell et al.
Daniel C Beachler et al.
Antibodies against the Human papillomavirus 16 (HPV16) E6 oncoprotein appear years prior to clinical diagnosis of anal and oropharyngeal cancer, but whether they develop around the time of HPV infection is unclear. Serum samples from 173 ca...
An analysis of HPV infection incidence and clearance by genotype and age in men: The HPV Infection in Men (HIM) Study [0.03%]
人乳头瘤病毒（HPV）感染型别和年龄分布及其消退特征——对男性中不同人乳头状瘤病毒感染率及消退情况的研究分析
Donna J Ingles,Hui-Yi Lin,William J Fulp et al.
Donna J Ingles et al.
Objectives: Genital HPV infection in men causes benign and cancerous lesions, the incidence of which differs by age. The goal of this work was to comprehensively evaluate incidence and clearance of individual HPV genotype...
Statewide analysis of missed opportunities for human papillomavirus vaccination using vaccine registry data [0.03%]
基于疫苗登记数据的全州范围HPV疫苗接种机会分析
Deanna Kepka,Michael G Spigarelli,Echo L Warner et al.
Deanna Kepka et al.
Background: Human papillomavirus (HPV) vaccine 3-dose completion rates among adolescent females in the US are low. Missed opportunities impede HPV vaccination coverage. ...