Potential normal tissue sparing in vulvar cancer using intensity modulated proton therapy versus volumetric modulated arc therapy [0.03%]
利用调强质子治癌与调强弧形治疗的潜在正常组织保护作用对比研究 Vulvar Cancer
Anna C Prins,Raymond de Boer,András G Zolnay et al.
Anna C Prins et al.
Background and purpose: Photon radiotherapy, typically volumetric modulated arc therapy (VMAT), is the standard for adjuvant or definitive treatment of vulvar cancer. Here, we explore the potential of intensity modulated ...
Metabolic and morphological assessment of carbon ion radiotherapy response in sacral chordoma [0.03%]
碳离子放疗对骶骨脊索瘤治疗反应的代谢和形态学评估
Burte Gantumur,Ayako Taketomi-Takahashi,Sayaka Kodaira et al.
Burte Gantumur et al.
Background and purpose: Sacral chordoma is a rare and locally aggressive malignant tumor. Carbon ion radiotherapy (CIRT) has emerged as a promising therapeutic modality, but tumor size may not decrease immediately after t...
Optimal radiotherapy dose scheduling with variable fraction sizes and breaks via sequential mixed-integer convex programming [0.03%]
具有可变分割大小和间歇期的最优放射治疗剂量安排的顺序混合整数凸编程方法
Anqi Fu,Zeno Gouw,Jeho Jeong et al.
Anqi Fu et al.
Background and purpose: Radiotherapy is typically delivered in consecutive equi-dose fractions, but research suggests a non-uniform dose schedule may produce a higher tumor control probability (TCP). We developed an optim...
Shear-wave ultrasound elastography for tissue-specific quantification of radiation-induced cervical fibrosis [0.03%]
剪切波超声弹性成像技术在放射性宫颈纤维化评估中的应用研究
Hendrik Dapper,Maria Waltenberger,Steffi U Pigorsch et al.
Hendrik Dapper et al.
Background and purpose: Radiation-induced cervical fibrosis is a common late effect following radiotherapy for head and neck cancer, potentially leading to reduced tissue compliance and functional impairment. Objective as...
Prospective blinded clinical evaluation of a fully automated workflow for prostate radiotherapy [0.03%]
全自动前列腺放疗流程的前瞻性临床评估
David Neugebauer,Jan-Hendrik Bolten,Hoi H Lau et al.
David Neugebauer et al.
Background and purpose: Fully automated workflows integrating deep learning-based segmentation and treatment planning have shown promising results in research settings but require prospective evaluation under routine clin...
Segmentation regularized training for multi-domain deep learning registration applied to magnetic resonance-guided prostate cancer radiotherapy [0.03%]
磁共振引导前列腺癌放射治疗的多域深度学习配准方法中的分割正则化训练法
Sudharsan Madhavan,Chengcheng Gui,Lando Bosma et al.
Sudharsan Madhavan et al.
Background and purpose: Accurate deformable image registration (DIR) is required for contour propagation and dose accumulation for magnetic resonance guided adaptive radiotherapy (MRgART). The goal of this study was to tr...
Robust framework for adaptive field-of-view automatic segmentation in vaginal brachytherapy for endometrial cancer [0.03%]
一种鲁棒的自适应视野分割框架用于子宫内膜癌阴道近距离放射治疗
Adrià Casamitjana,Ana María Gómez Fresco,Cristian Candela-Juan et al.
Adrià Casamitjana et al.
Background and purpose: The lack of robust automatic tools for segmentation in vaginal brachytherapy (VBT) limits efficiency and reproducibility in clinical practice. We aimed to develop a framework for automatic segmenta...
Deep learning for dose-averaged linear energy transfer estimation in pencil-beam scanning and double scattering proton radiotherapy plans with uncertainty-aware external validation [0.03%]
具有不确定性意识的外部验证的笔形束扫描和双散射质子放射治疗计划的深度学习平均线性能量传递估算
Aaron Kieslich,Yerik Singh,Martina Palkowitsch et al.
Aaron Kieslich et al.
Background and purpose: Accounting for the linear energy transfer (LET) in proton radiotherapy may reduce treatment-related side effects. When Monte Carlo (MC) simulations are unavailable, deep-learning (DL) surrogate mod...
Feasibility of longitudinal relaxation rate mapping with non-Cartesian sampling and compressed sensing on a 1.5 T magnetic resonance linear accelerator [0.03%]
基于非笛卡尔采样和压缩感知的1. 5T磁共振直线加速器纵向弛豫率图谱研究的可能性评估
Lucas McCullum,Michael J van Rijssel,Ken-Pin Hwang et al.
Lucas McCullum et al.
Background and purpose: Quantitative T1 mapping is a major building block in several multiparametric magnetic resonance imaging (MRI) protocols intended for adaptive radiation therapy. The implementation of these protocol...
Clinical implementation and impact of real-time Cherenkov imaging for treatment verification and patient safety in radiation therapy [0.03%]
实时切伦科夫成像在放射治疗中的临床应用及对治疗验证和患者安全的影响
Adi Robinson,Michael Tallhamer
Adi Robinson
Background and purpose: Real-time Cherenkov imaging (CI) visualizes surface dose distribution during external beam radiotherapy (EBRT). Although feasibility has been demonstrated, sustained multi-site implementation with ...