Sarcopenic obesity in the Asia-Pacific region: Epidemiology, risk factors, and management [0.03%]
亚太地区的少肌性肥胖症的流行病学、风险因素和管理方法
Chun-Feng Huang,Chih-Hsing Wu
Chun-Feng Huang
Sarcopenic obesity (SO), characterized by the concurrent presence of sarcopenia and obesity, is an emerging public health challenge in the Asia-Pacific region. With rapid population aging and increasing obesity rates, the prevalence of SO i...
Bone-muscle interactions [0.03%]
骨肌相互作用
Hiroshi Kaji
Hiroshi Kaji
Bone and skeletal muscle jointly govern motor function, working in coordination as anatomically adjacent organs, and collaborate with through mechanical interactions. Bone and muscle cells are both derived from common mesenchymal stem cells...
Advancing muscle aging and sarcopenia research through spatial transcriptomics [0.03%]
通过空间转录组学推进肌肉衰老和肌少症研究
Byeong-Don Min,Chae Young Hwang,Doyeong Kim et al.
Byeong-Don Min et al.
Sarcopenia, defined as a decline of muscle mass and function with aging, poses significant health challenges. This decline is driven by multiple factors including cellular dysfunction, mitochondrial impairments, oxidative stress, and chroni...
Sarcopenia prevention in older adults: Effectiveness and limitations of non-pharmacological interventions [0.03%]
老年人 sarcopenia 的非药物干预的有效性和局限性
Doyoon Kim,Satoru Morikawa,Masashi Miyawaki et al.
Doyoon Kim et al.
Sarcopenia is characterized by a decline in skeletal muscle mass, strength, and physical performance in older adults and is associated with reduced quality of life, an increased risk of requiring long-term care, and a significant economic b...
Seiji Hashimoto,Tatsuya Hosoi,Mitsutaka Yakabe et al.
Seiji Hashimoto et al.
With increasing life expectancy, the aging population grows, leading to more age-related diseases. Among these, falls are a serious public health issue, as they cause disability in older adults and impose a significant burden both on caregi...
Tzu-Hao Tseng,Shau-Huai Fu,Ning-Huei Sie et al.
Tzu-Hao Tseng et al.
Sarcopenia is a progressive loss of skeletal muscle mass and strength that contributes to adverse outcomes such as falls, fractures, and mortality in aging populations. Its prevalence varies widely across studies, influenced by intrinsic fa...
Fracture risk in Korean postmenopausal women: The influence of BMI, age, and bone density [0.03%]
韩国绝经后妇女骨折风险：体质指数、年龄和骨密度的影响
Junghwa Shin,Kwang Yoon Kim,Joo-Hyun Park et al.
Junghwa Shin et al.
Objectives: Fracture risk in postmenopausal women is influenced by bone mineral density (BMD), age, and body mass index (BMI). However, fracture prevention strategies primarily focus on low BMD, often overlooking other ke...
Are there associations between bone turnover and hip geometry in the general population? [0.03%]
一般人群中骨转换与髋关节几何形状有关吗？
Cornelius Sebastian Fischer,Till Ittermann,Sarah Kalmbach et al.
Cornelius Sebastian Fischer et al.
Objectives: While impaired bone remodeling contributes to osteoporosis and probably to osteoarthritis, the relations between bone turnover and key hip geometry measures such as center-edge angle (CE), neck-shaft angle (NS...
Femoral bone mineral density reference values by sex and ethnicity: Findings from the Qatar Biobank study [0.03%]
民族和性别特定的股骨骨密度参考值：卡塔尔生物银行研究的结果
Fawziya Al-Baker,Mujahed Shraim,Amal Al-Haidose et al.
Fawziya Al-Baker et al.
Objectives: Low bone mineral density (BMD) is a major global health concern due to fracture-related morbidity and mortality. BMD is currently assessed by dual-energy X-ray absorptiometry (DXA) against a US reference popul...
Molecular crosstalk in SP7-mediated osteogenesis: Regulatory mechanisms and therapeutic potential [0.03%]
SP7介导的骨发生的分子交叉谈话：调控机制和治疗潜力
Jun Lang,Vivek Kumar Morya,Mi-Kyung Kwak et al.
Jun Lang et al.
SP7, also known as Osterix, is a zinc finger-containing transcription factor, plays a crucial role in osteoblast differentiation and bone formation. This review examines the molecular mechanisms underlying SP7's regulatory functions, highli...