Engineering biology and automation-Replicability as a design principle [0.03%]
工程生物学和自动化——以可重复性为设计原则
Matthieu Bultelle,Alexis Casas,Richard Kitney
Matthieu Bultelle
Applications in engineering biology increasingly share the need to run operations on very large numbers of biological samples. This is a direct consequence of the application of good engineering practices, the limited predictive power of cu...
Sébastien Lambertucci,Faye Deakin
Sébastien Lambertucci
Breakthroughs in engineering biology will solve the challenges facing humanity, by harnessing life itself. Standing in the way of these breakthroughs are the technical challenges of collecting the requisite data. Data variability and reprod...
Routes to industrial scalability to maximise investment in engineering biology in the UK-A bioplastics small and medium-sized enterprise perspective [0.03%]
英国工程生物学投资最大化的工业规模化道路——生物塑料中小企业视角
Amy Switzer,Laima Šusta,Paul Mines
Amy Switzer
Focus on engineering biology is at the forefront of the UK government's objectives, being one of their five critical technologies (the others being quantum technologies, artifical intelligence, semiconductors, and future telecommunications)...
David Bell
David Bell
Since joining SynbiCITE, the national centre for translating synthetic biology, a decade ago as the lone analytical chemist, the centre has gone from limited lab space to playing its part in securing funding, growth and development of more ...
Programmable cancer treatments: Engineering biology approaches for living cures [0.03%]
可编程癌症治疗：用于“活体治愈”的工程生物学方法
Marc Biarnes Carrera,Alexandra Sevko,Nicholas Glanville et al.
Marc Biarnes Carrera et al.
Living cures are cell-based, programmable therapies that integrate the latest learnings in immunology and synthetic biology. Although Adoptive Cell Therapies (ACTs) have transformed the treatment landscape of haematological malignancies by ...
Building the bioeconomy: A targeted assessment approach to identifying biobased technologies, challenges and opportunities [0.03%]
构建生物经济：识别基于生物质技术、挑战和机遇的定向评估方法
Claire Holland,Philip Shapira
Claire Holland
The authors explore opportunities, challenges, and strategies to translate and responsibly scale innovative biobased technologies to build more sustainable bioeconomies. The pandemic and other recent disruptions increased exposure to issues...
Analysing responsible innovation along a value chain-A single-cell protein case study [0.03%]
价值链视角下负责任创新的分析——以单细胞蛋白案例研究为例
Monica Hoyos Flight,Joyce Tait,Theo Chronopoulos et al.
Monica Hoyos Flight et al.
The British Standards Institution's Publicly Available Specification 440 (PAS 440) provides a Responsible Innovation Framework (RIF) that companies can use to continuously monitor the societal, environmental and health benefits and risks of...
Case Reports
Engineering biology. 2024 Mar 20;8(1):16-29. DOI:10.1049/enb2.12031 2024
Designing of an extract production protocol for industrial application of cell-free protein synthesis technology: Building from a current best practice to a quality by design approach [0.03%]
无细胞蛋白质合成技术工业应用的提取物生产规程设计：从当前最佳实践到基于质量的设计方法
Beatrice Judith Melinek,Jade Tuck,Philip Probert et al.
Beatrice Judith Melinek et al.
Cell-Free Protein Synthesis (CFPS) has, over the past decade, seen a substantial increase in interest from both academia and industry. Applications range from fundamental research, through high-throughput screening to niche manufacture of t...
Protein engineering in the computational age: An open source framework for exploring mutational landscapes in silico [0.03%]
计算时代下的蛋白质工程：探索突变景观的开源框架
Shirin Bamezai,Giovanni Maresca di Serracapriola,Freya Morris et al.
Shirin Bamezai et al.
The field of protein engineering has seen tremendous expansion in the last decade, with researchers developing novel proteins with specialised functionalities for a range of uses, from drug discovery to industrial biotechnology. The emergen...
Yuval Dorfan,Aviv Zeevi,Gita Reinitz et al.
Yuval Dorfan et al.
The field of synthetic biology emerged a few decades ago, following some key works of researchers in the USA, Europe, and the Far East. It reached Israel through academia and a few years later it finally got the attention of industry, ventu...