Nuclear mechanosensing [0.03%]
核机械感受性
Yuntao Xia,Charlotte R Pfeifer,Sangkyun Cho et al.
Yuntao Xia et al.
Structural links from the nucleus to the cytoskeleton and to the extracellular environment play a role in direct mechanosensing by nuclear factors. Here, we highlight recent studies that illustrate nuclear mechanosensation processes ranging...
Abdullah R Alanzi,Ananiya A Demessie,Taifo Mahmud
Abdullah R Alanzi
Pseudo-oligosaccharides are microbial-derived secondary metabolites whose chemical structures contain pseudosugars (glycomimetics). Due to their high resemblance to the molecules of life (carbohydrates), most pseudo-oligosaccharides show si...
Targeted therapies for congenital myasthenic syndromes: systematic review and steps towards a treatabolome [0.03%]
针对先天性肌无力综合征的靶向治疗：系统综述及通向治疗abolome的步骤
Rachel Thompson,Gisèle Bonne,Paolo Missier et al.
Rachel Thompson et al.
Despite recent scientific advances, most rare genetic diseases - including most neuro-muscular diseases - do not currently have curative gene-based therapies available. However, in some cases, such as vitamin, cofactor or enzyme deficiencie...
Richard McCulloch,Christina A Cobbold,Luisa Figueiredo et al.
Richard McCulloch et al.
Many pathogens evade host immunity by periodically changing the proteins they express on their surface - a phenomenon termed antigenic variation. An extreme form of antigenic variation, based around switching the composition of a Variant Su...
Brent L Nannenga,Tamir Gonen
Brent L Nannenga
Micro-electron diffraction, or MicroED, is a structure determination method that uses a cryo-transmission electron microscope to collect electron diffraction data from nanocrystals. This technique has been successfully used to determine the...
Patrick C A van der Wel
Patrick C A van der Wel
Various recent developments in solid-state nuclear magnetic resonance (ssNMR) spectroscopy have enabled an array of new insights regarding the structure, dynamics, and interactions of biomolecules. In the ever more integrated world of struc...
Can't you hear me knocking: contact-dependent competition and cooperation in bacteria [0.03%]
你能听到我在敲门吗：细菌接触依赖性竞争与合作
Allison M Jones,David A Low,Christopher S Hayes
Allison M Jones
Microorganisms are in constant competition for growth niches and environmental resources. In Gram-negative bacteria, contact-dependent growth inhibition (CDI) systems link the fate of one cell with its immediate neighbor through touch-depen...