Signaling mechanisms that direct cell fate specification and morphogenesis in human embryonic stem cells-based models of human gastrulation [0.03%]
基于人类胚胎干细胞的人类原肠运动的细胞命运决定及形态发生的信号机制研究
Blerta Stringa,Lilianna Solnica-Krezel
Blerta Stringa
During mammalian gastrulation, a mass of pluripotent cells surrounded by extraembryonic tissues differentiates into germ layers, mesoderm, endoderm, and ectoderm. The three germ layers are then organized into a body plan with organ rudiment...
Camil Mirdass,Martin Catala,Mikaëlle Bocel et al.
Camil Mirdass et al.
Neurulation is a critical step in early embryonic development, giving rise to the neural tube, the primordium of the central nervous system in amniotes. Understanding this complex, multi-scale, multi-tissue morphogenetic process is essentia...
Michelle A Miller,Nathan E Howarth
Michelle A Miller
This review centres around the recent evidence in examining the intersection of sleep and cardiovascular disease (CVD). Sleep in this review will be further subdivided to consider both sleep quantity and quality along and will also consider...
Paul Gepts
Paul Gepts
Biocultural diversity is the ever-evolving and irreplaceable sum total of all living organisms inhabiting the Earth. It plays a significant role in sustainable productivity and ecosystem services that benefit humanity and is closely allied ...
Pierre-François Lenne,Sham Tlili
Pierre-François Lenne
Gastruloids acquire their organization and shape through cell biochemical and mechanical activities. Such activities determine the physical forces and changes in material properties that transform simple spherical aggregates into organized ...
Marcus O Harrington,Sarah Reeve,Joanne L Bower et al.
Marcus O Harrington et al.
Depression is associated with general sleep disturbance and abnormalities in sleep physiology. For example, compared with control subjects, depressed patients exhibit lower sleep efficiency, longer rapid eye movement (REM) sleep duration, a...
Dan Denis,Scott A Cairney
Dan Denis
Sleep promotes memory consolidation: the process by which newly acquired memories are stabilised, strengthened, and integrated into long-term storage. Pioneering research in rodents has revealed that memory reactivation in sleep is a primar...
The nitric oxide paradox: antimicrobial and inhibitor of antibiotic efficacy [0.03%]
硝酸盐的两面性：抗菌和抑制抗生素效力
Calum M Webster,Mark Shepherd
Calum M Webster
It is well-known that antibiotics target energy-consuming processes and a significant body of research now supports the conclusion that the metabolic state of bacteria can have a profound impact upon the efficacy of antibiotics. Several art...
Endosphere microbial communities and plant nutrient acquisition toward sustainable agriculture [0.03%]
根系微生物组与植物养分获取及可持续农业
Olubukola Oluranti Babalola,Afeez Adesina Adedayo
Olubukola Oluranti Babalola
Endophytic microbial communities have essential information for scientists based on their biological contribution to agricultural practices. In the external plant environment, biotic and abiotic factors affect microbial populations before g...
Maryke Labuschagne
Maryke Labuschagne
Crop biofortification has significantly progressed in the last few decades. The first biofortification success was quality protein maize, leading to double the amount of the essential amino acids lysine and tryptophan. This was followed by ...