BioRxToolbox: a computational framework to streamline genetic circuit design in molecular data communications [0.03%]
BioRxToolbox：一种计算框架，可简化分子数据通信中的遗传电路设计
Merve Gorkem Durmaz,Neval Tulluk,Recep Deniz Aksoy et al.
Merve Gorkem Durmaz et al.
Developments in bioengineering and nanotechnology have ignited the research on biological and molecular communication systems. Despite potential benefits, engineering communication systems to carry data signals using biological messenger mo...
In- & Out-Cloning: plasmid toolboxes for scarless transcription unit and modular Golden Gate acceptor plasmid assembly [0.03%]
无疤转录单元和模块化Golden Gate接受者质粒装配的质粒工具箱：进出克隆技术
Stijn T de Vries,Tania S Köbel,Ahmet Sanal et al.
Stijn T de Vries et al.
Golden Gate cloning has become one of the most important DNA assembly strategies. The construction of standardized and reusable part libraries, their assembly into transcription units, and the subsequent assembly of multigene constructs is ...
Casey-Tyler Berezin
Casey-Tyler Berezin
In vitro transcription-based biosensing of glycolate for prototyping of a complex enzyme cascade [0.03%]
基于体外转录的甘油酸复杂酶级联原型器件的生物传感技术
Sebastian Barthel,Luca Brenker,Christoph Diehl et al.
Sebastian Barthel et al.
In vitro metabolic systems allow the reconstitution of natural and new-to-nature pathways outside of their cellular context and are of increasing interest in bottom-up synthetic biology, cell-free manufacturing, and metabolic engineering. Y...
Cell-free synthesis of infective phages from in vitro assembled phage genomes for efficient phage engineering and production of large phage libraries [0.03%]
无细胞合成感染性噬菌体用于高效噬菌体工程和大量噬菌体文库的生产
Camilla S Kristensen,Anders Ø Petersen,Mogens Kilstrup et al.
Camilla S Kristensen et al.
Bacteriophages are promising alternatives to traditional antimicrobial treatment of bacterial infections. To further increase the potential of phages, efficient engineering methods are needed. This study investigates an approach to phage en...
Anna Matuszyńska,Oliver Ebenhöh,Matias D Zurbriggen et al.
Anna Matuszyńska et al.
Synthetic biology conceptualizes biological complexity as a network of biological parts, devices, and systems with predetermined functionalities and has had a revolutionary impact on fundamental and applied research. With the unprecedented ...
Natalie R Zelenka,Nina Di Cara,Kieren Sharma et al.
Natalie R Zelenka et al.
Data science is playing an increasingly important role in the design and analysis of engineered biology. This has been fueled by the development of high-throughput methods like massively parallel reporter assays, data-rich microscopy techni...
Alexis Casas,Matthieu Bultelle,Richard Kitney
Alexis Casas
The paper addresses the application of engineering biology strategies and techniques to the automation of laboratory workflow-primarily in the context of biofoundries and biodesign applications based on the Design, Build, Test and Learn par...
Navigating the 'moral hazard' argument in synthetic biology's application [0.03%]
合成生物学应用中的“道德风险”问题探究
Christopher Hunter Lean
Christopher Hunter Lean
Synthetic biology has immense potential to ameliorate widespread environmental damage. The promise of such technology could, however, be argued to potentially risk the public, industry or governments not curtailing their environmentally dam...