Erratum to: A MATLAB toolbox for modeling genetic circuits in cell-free systems [0.03%]
关于MATLAB在无细胞系统中建模遗传回路的工具箱的勘误注释
Vipul Singhal,Zoltan A Tuza,Zachary Z Sun et al.
Vipul Singhal et al.
[This corrects the article DOI: 10.1093/synbio/ysab007.]. © The Author(s) 2021. Published by Oxford University Press.
Published Erratum
Synthetic biology (Oxford, England). 2021 Aug 21;6(1):ysab016. DOI:10.1093/synbio/ysab016 2021
Synthesis of libraries and multi-site mutagenesis using a PCR-derived, dU-containing template [0.03%]
利用含有dU的PCR衍生模板进行库合成及多位点诱变
Gretchen Meinke,Nahide Dalda,Benjamin S Brigham et al.
Gretchen Meinke et al.
Directed DNA libraries are useful because they focus genetic diversity in the most important regions within a sequence. Ideally, all sequences in such libraries should appear with the same frequency and there should be no significant backgr...
Aquarium: open-source laboratory software for design, execution and data management [0.03%]
Aquarium：一种开源实验室软件，用于设计、执行和数据管理
Justin Vrana,Orlando de Lange,Yaoyu Yang et al.
Justin Vrana et al.
Automation has been shown to improve the replicability and scalability of biomedical and bioindustrial research. Although the work performed in many labs is repetitive and can be standardized, few academic labs can afford the time and money...
A MATLAB toolbox for modeling genetic circuits in cell-free systems [0.03%]
用于细胞自由系统中建模遗传电路的MATLAB工具箱
Vipul Singhal,Zoltan A Tuza,Zachary Z Sun et al.
Vipul Singhal et al.
We introduce a MATLAB-based simulation toolbox, called txtlsim, for an Escherichia coli-based Transcription-Translation (TX-TL) system. This toolbox accounts for several cell-free-related phenomena, such as resource loading, consumption and...
Transcriptional control of Clostridium autoethanogenum using CRISPRi [0.03%]
用于控制Clostridium autoethanogenum转录的CRISPRi系统
Nicholas Fackler,James Heffernan,Alex Juminaga et al.
Nicholas Fackler et al.
Gas fermentation by Clostridium autoethanogenum is a commercial process for the sustainable biomanufacturing of fuels and valuable chemicals using abundant, low-cost C1 feedstocks (CO and CO2) from sources such as inedible biomass, unsorted...
Building a biofoundry [0.03%]
打造生物制造工厂
Maciej B Holowko,Emma K Frow,Janet C Reid et al.
Maciej B Holowko et al.
A biofoundry provides automation and analytics infrastructure to support the engineering of biological systems. It allows scientists to perform synthetic biology and aligned experimentation on a high-throughput scale, massively increasing t...
Mingqi Xie,Mirta Viviani,Martin Fussenegger
Mingqi Xie
In the past decade, gene- and cell-based therapies have been at the forefront of the biomedical revolution. Synthetic biology, the engineering discipline of building sophisticated 'genetic software' to enable precise regulation of gene acti...
A platform for post-translational spatiotemporal control of cellular proteins [0.03%]
用于蛋白质时空转录后控制的平台
Brianna Jayanthi,Bhagyashree Bachhav,Zengyi Wan et al.
Brianna Jayanthi et al.
Mammalian cells process information through coordinated spatiotemporal regulation of proteins. Engineering cellular networks thus relies on efficient tools for regulating protein levels in specific subcellular compartments. To address the n...
Pablo Cárdenas
Pablo Cárdenas