Relating DNA base-pairing in aqueous media to DNA polymerase fidelity [0.03%]
DNA溶液中的碱基配对与DNA聚合酶保真性之间的关系
John Petruska,Myron F Goodman
John Petruska
Controversy surrounds the perceived absence of a relationship between DNA polymerase fidelity (kinetic discrimination) and free energy changes determined from DNA melting studies (thermodynamic discrimination). Thermodynamic discrimination ...
Jonathan W Lehmann,Daniel J Blair,Martin D Burke
Jonathan W Lehmann
Small molecules have extensive untapped potential to benefit society, but access to this potential is too often restricted by limitations inherent to the customized approach currently used to synthesize this class of chemical matter. In con...
Nilay Hazari,Patrick R Melvin,Megan Mohadjer Beromi
Nilay Hazari
Transition metal-catalysed cross-coupling is one of the most powerful synthetic methods and has led to vast improvements in the synthesis of pharmaceuticals, agrochemicals and precursors for materials chemistry. A major advance in cross-cou...