Enhancing non-LR-5 liver lesion diagnoses: the incremental value of serum alpha-fetoprotein and PIVKA-II for detecting hepatocellular carcinoma components [0.03%]
增强非LR-5肝病变诊断：血清甲胎蛋白和PIVKA-II检测肝细胞癌成分的增量价值评估
Junghoan Park,Jeong Min Lee,Rae Rim Ryu et al.
Junghoan Park et al.
Backgrounds/aims: To investigate whether incorporating serum alpha-fetoprotein (AFP) and protein induced by vitamin K absence or antagonist-II (PIVKA-II) into gadoxetic acid-enhanced liver MRI improves the accuracy of dif...
Outcomes of Early-Stage HCC patients treated by resection or ablation: real-life data from the French administrative health care database (SNDS) [0.03%]
基于法国卫生行政数据库（SNDS）的早期肝细胞癌患者手术或局部消融治疗预后的现实世界研究数据
Marie Decraecker,Boris Guiu,Emmanuel Boleslawski et al.
Marie Decraecker et al.
Background/aims: Surgical resection and percutaneous ablation are considered curative treatments for hepatocellular carcinoma (HCC). However, both approaches are associated with a high risk of recurrence. Real-world data ...
Pain, analgesic use and misconceptions in patients with hepatocellular carcinoma: a cross-sectional survey [0.03%]
肝细胞癌患者疼痛、止痛药使用及认识误区的横断面调查研究
Jina Park,Jiwon Yang,Sung Won Chung et al.
Jina Park et al.
Background/aims: Cancer-related pain remains undertreated despite established guidelines. In hepatocellular carcinoma (HCC), underlying chronic liver disease may amplify concerns regarding analgesic safety. We aimed to ev...
Combined hepatocellular-cholangiocarcinoma: a contemporary pathologic and molecular perspective [0.03%]
结合肝细胞癌和胆管癌的病理及分子特征的当代研究视角
Taek Chung
Taek Chung
Combined hepatocellular cholangiocarcinoma (cHCC-CCA) is a rare primary liver carcinoma characterized by the unequivocal coexistence of hepatocytic and cholangiocytic differentiation within a single tumor. Despite its low incidence, cHCC-CC...
Alcohol-related hepatocellular carcinoma: Surveillance and primary prevention [0.03%]
酒精相关肝细胞癌的筛查和一级预防
Gianni Testino
Gianni Testino
The role of radiotherapy in the management of combined hepatocellular-cholangiocarcinoma: current evidence and future perspectives [0.03%]
放疗在肝细胞癌-胆管癌混合型肿瘤治疗中的作用：现有证据及未来展望
Seo Hee Choi,Woong Sub Koom,Ik Jae Lee
Seo Hee Choi
Combined hepatocellular-cholangiocarcinoma (cHCC-CCA) is a rare and highly aggressive hybrid malignancy characterized by a poor prognosis and high recurrence rates due to its dual histological nature. In the absence of established standard-...
Imaging differentiation of hepatocellular carcinoma, combined hepatocellular-cholangiocarcinoma, and intrahepatic cholangiocarcinoma: pitfalls and advances [0.03%]
肝细胞癌、混合性肝细胞-胆管癌和肝内胆管癌的影像鉴别：陷阱与进展
Jaeseung Shin,Taek Chung,Sang Yun Ha et al.
Jaeseung Shin et al.
Accurate non-invasive differentiation of primary liver cancers, such as hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (iCCA), and combined hepatocellular-cholangiocarcinoma (cHCC-CCA), is crucial for optimal management but...
Contemporary overview of liver transplantation for intrahepatic cholangiocarcinoma and combined hepatocellular-cholangiocarcinoma [0.03%]
现代肝移植治疗肝内胆管癌和混合型肝细胞-胆管癌综述
Hae Won Lee
Hae Won Lee
Historically, intrahepatic cholangiocarcinoma (iCCA) and combined hepatocellular-cholangiocarcinoma (cHCC-CCA) were regarded as absolute contraindications for liver transplantation (LT) due to dismal outcomes characterized by high recurrenc...
Systemic therapy for combined hepatocellular-cholangiocarcinoma: a comprehensive review of chemotherapy, immunotherapy, and targeted therapy [0.03%]
结合肝细胞癌和胆管癌的系统治疗：化疗、免疫治疗和靶向治疗综述
Jung Yong Hong,Dong Hyun Sinn,Sang Yun Ha
Jung Yong Hong
Combined hepatocellular-cholangiocarcinoma (cHCC-CCA) is a rare primary liver malignancy exhibiting both hepatocytic and cholangiocytic differentiation. Since the 2019 World Health Organization (WHO) reclassification, growing molecular and ...
Systemic treatment strategies for combined hepatocellular-cholangiocarcinoma: current evidence and future direction [0.03%]
结合肝细胞癌和胆管癌的系统治疗策略：现有证据及未来方向
Jeesun Yoon
Jeesun Yoon
Combined hepatocellular-cholangiocarcinoma is a rare primary liver malignancy characterized by biphenotypic differentiation and marked biologic heterogeneity. Owing to its low incidence, diagnostic complexity, and lineage plasticity, standa...