Assessing Treatment Response of Glioblastoma to an HDAC Inhibitor Using Whole-Brain Spectroscopic MRI [0.03%]
使用全脑光谱磁共振成像评估组蛋白去乙酰化酶抑制剂治疗胶质母细胞瘤的疗效
Saumya S Gurbani,Younghyoun Yoon,Brent D Weinberg et al.
Saumya S Gurbani et al.
Histone deacetylases regulate a wide variety of cellular functions and have been implicated in redifferentiation of various tumors. Histone deacetylase inhibitors (HDACi) are potential pharmacologic agents to improve outcomes for patients w...
Controlled Clinical Trial
Tomography (Ann Arbor, Mich.). 2019 Mar;5(1):53-60. DOI:10.18383/j.tom.2018.00031 2019
Magnetization Transfer MRI of Breast Cancer in the Community Setting: Reproducibility and Preliminary Results in Neoadjuvant Therapy [0.03%]
社区乳腺癌磁化转移MRI的重复性及其在新辅助治疗中的初步结果
John Virostko,Anna G Sorace,Chengyue Wu et al.
John Virostko et al.
Repeatability and reproducibility of magnetization transfer magnetic resonance imaging of the breast, and the ability of this technique to assess the response of locally advanced breast cancer to neoadjuvant therapy (NAT), are determined. R...
Multicenter Repeatability Study of a Novel Quantitative Diffusion Kurtosis Imaging Phantom [0.03%]
多中心新型扩散曲率成像定量 phantom 重复性研究
Dariya I Malyarenko,Scott D Swanson,Amaresha S Konar et al.
Dariya I Malyarenko et al.
Quantitative kurtosis phantoms are sought by multicenter clinical trials to establish accuracy and precision of quantitative imaging biomarkers on the basis of diffusion kurtosis imaging (DKI) parameters. We designed and evaluated precision...
Multicenter Study
Tomography (Ann Arbor, Mich.). 2019 Mar;5(1):36-43. DOI:10.18383/j.tom.2018.00030 2019
Quantitative Non-Gaussian Intravoxel Incoherent Motion Diffusion-Weighted Imaging Metrics and Surgical Pathology for Stratifying Tumor Aggressiveness in Papillary Thyroid Carcinomas [0.03%]
定量非高斯亚 voxel 不相干运动扩散加权成像指标和手术病理学对乳头状甲状腺癌肿瘤侵袭性的分层
David Aramburu Núñez,Yonggang Lu,Ramesh Paudyal et al.
David Aramburu Núñez et al.
We assessed a priori aggressive features using quantitative diffusion-weighted imaging metrics to preclude an active surveillance management approach in patients with papillary thyroid cancer (PTC) with tumor size 1-2 cm. This prospective s...
Repeatability of Quantitative Diffusion-Weighted Imaging Metrics in Phantoms, Head-and-Neck and Thyroid Cancers: Preliminary Findings [0.03%]
体模、头颈部和甲状腺癌症中定量弥散加权成像的重复性：初步研究发现
Ramesh Paudyal,Amaresha Shridhar Konar,Nancy A Obuchowski et al.
Ramesh Paudyal et al.
The aim of this study was to establish the repeatability measures of quantitative Gaussian and non-Gaussian diffusion metrics using diffusion-weighted imaging (DWI) data from phantoms and patients with head-and-neck and papillary thyroid ca...
Comparison of Voxel-Wise and Histogram Analyses of Glioma ADC Maps for Prediction of Early Therapeutic Change [0.03%]
基于胶质瘤ADC图的体素分析和直方图分析对预测早期治疗变化的对比研究
Thomas L Chenevert,Dariya I Malyarenko,Craig J Galbán et al.
Thomas L Chenevert et al.
Noninvasive imaging methods are sought to objectively predict early response to therapy for high-grade glioma tumors. Quantitative metrics derived from diffusion-weighted imaging, such as apparent diffusion coefficient (ADC), have previousl...
Comparative Study
Tomography (Ann Arbor, Mich.). 2019 Mar;5(1):7-14. DOI:10.18383/j.tom.2018.00049 2019
Keyvan Farahani,Darrell Tata,Robert J Nordstrom
Keyvan Farahani
The Quantitative Imaging Network of the National Cancer Institute is in its 10th year of operation, and research teams within the network are developing and validating clinical decision support software tools to measure or predict the respo...
Evaluation of Virtual Reality for Detection of Lung Nodules on Computed Tomography [0.03%]
基于虚拟现实的CT肺结节检测性能评估研究
Brian J Nguyen,Aman Khurana,Brendon Bagley et al.
Brian J Nguyen et al.
Virtual reality (VR) systems can offer benefits of improved ergonomics, but their resolution may currently be limited for the detection of small features. For detection of lung nodules, we compared the performance of VR versus standard pict...
Keith A Cauley,Samuel W Fielden
Keith A Cauley
Multiple sclerosis (MS) is a progressive neurodegenerative disease, affecting 1 million Americans and 2.5 million people globally. Although the diagnosis is made clinically, imaging plays a major role in diagnosing and monitoring disease pr...
Pitfalls in Gallium-68 PSMA PET/CT Interpretation-A Pictorial Review [0.03%]
镓-68 PSMA PET/CT影像诊断陷阱-图解回顾
Deepa Shetty,Dhruv Patel,Ken Le et al.
Deepa Shetty et al.
The novel Gallium-68 prostate-specific membrane antigen (PSMA)-bis [2-hydroxy-5-(carboxyethyl)benzyl] ethylenediamine-diacetic acid positron emission tomography (PET) tracer is increasingly used in the evaluation of prostate cancer, particu...