Cannabidiol Pretreatment Reduces Status Epilepticus and Glutamate Uptake Induced by Kainic Acid in Adult Zebrafish [0.03%]
大麻二酚预处理可减少氯化氪酸诱导的成年斑马鱼癫痫持续状态和谷氨酸摄取
Karolyne de Pieri Pickler,Ana Caroline Salvador de Farias,Guilherme Lodetti et al.
Karolyne de Pieri Pickler et al.
Background: Epilepsy is a neurological chronic disorder that affects about 70 million people worldwide. Status epilepticus (SE) are neural disturbances that cause intense glutamatergic excitatory discharges that modulate changes in normal b...
Feasibility and Tolerability of Nabilone for the Treatment of Obesity: A Randomized Controlled Pilot Trial [0.03%]
纳博灵治疗肥胖症的可行性及耐受性:一项随机对照试点试验
Justin Matheson,Dominique Tertigas,Saima Malik et al.
Justin Matheson et al.
Introduction: In epidemiological studies, people who use cannabis have a lower prevalence of obesity. Furthermore, the endocannabinoid system is recognized as a potential target for obesity treatment and partial agonism of the cannabinoid t...
Cost-Effectiveness of Medical Cannabis Versus Opioids for Chronic Noncancer Pain [0.03%]
大麻类药物与阿片类药物治疗慢性非癌痛的成本效益分析
Haron M Jeddi,Jason W Busse,Behnam Sadeghirad et al.
Haron M Jeddi et al.
Background: Chronic noncancer pain (CNCP) affects one in five adults and is commonly managed with long-term opioid therapy. Concerns regarding rare but catastrophic harms associated with opioids, including overdose and death, have generated...
Acid-Catalyzed Conversion of Cannabidiol to Tetrahydrocannabinols: En Route to Demystifying Manufacturing Processes and Controlling the Reaction Outcomes [0.03%]
CBD到 THC的酸催化转化:揭秘制造过程和控制反应结果之旅
Alex Nivorozhkin,Michael G Palfreyman
Alex Nivorozhkin
Background: Over the last decade, there has been a significant increase in the production of multiple tetrahydrocannabidiol (THC) related products via the acid catalysis of cannabidiol (CBD). The widespread availability of CBD and the unreg...
Health Care Providers' Knowledge, Attitudes, and Practices Toward Medicinal Cannabis: The Case of Lebanon [0.03%]
医疗保健人员对医用大麻的认知、态度和行为:来自黎巴嫩的案例
Bassima Hazimeh,Ibrahim Bou-Orm,Mohamad Mroueh et al.
Bassima Hazimeh et al.
Background: In 2020, the Lebanese parliament legalized cannabis for medical and industrial use, sparking diverse reactions among health care professionals (HCP). Few studies have been conducted to reflect the position of HCP on the topic, a...
Pharmacokinetics and Bioavailability of Cannabinoids Administered via a Novel Orobuccal Nanoparticle Formulation (NanoCelle™) in Patients with Advanced Cancer [0.03%]
通过新型口腔纳米颗粒配方(NanoCelle™)给药的大麻素的药代动力学和生物利用度在晚期癌症患者中的研究
Stephanie E Reuter,Hayley B Schultz,Andrew J McLachlan et al.
Stephanie E Reuter et al.
Introduction: The administration of cannabinoids for disease and symptom management such as pain continues to elicit significant interest, albeit limited information that is available regarding their pharmacokinetics and pharmacodynamics to...
Estimating the Price Elasticity of Cannabis Use Among U.S. Adults: Evidence from States with Recreational Cannabis Commercialization [0.03%]
美国成年人大麻使用价格弹性的估计:来自娱乐用大麻商业化的州的证据
Bing Han,Hojin Park,Yanyun He et al.
Bing Han et al.
Introduction: Following the spread of recreational cannabis legalization and commercialization, cannabis has become increasingly available at lower prices. As policies regulating prices are common tools to control the demand for commerciali...
Neighborhood Sociodemographic Correlates of Cannabis Dispensary Availability in States with Legalized Adult Recreational Use, United States, 2021 [0.03%]
美国2021年大麻销售点的可及性与邻里社会人口统计学特征的关系研究
Bryce C Lowery,Madison R E Swayne,Amanda Y Kong
Bryce C Lowery
Introduction: The availability of recreational cannabis in the United States has increased dramatically. Neighborhood cannabis dispensary availability may increase problematic use. State and local studies suggest that cannabis dispensary av...
A Pilot Randomized Placebo-Controlled Crossover Trial of Medicinal Cannabis in Adolescents with Tourette Syndrome [0.03%]
青少年妥瑞症患者医用大麻的试点随机安慰剂对照交叉试验
Daryl Efron,Kaitlyn Taylor,Eunice Chan et al.
Daryl Efron et al.
Introduction: Medicinal cannabis (MC) has potential therapeutic effects in Tourette Syndrome (TS), however there has been limited research in adolescent patients. This pilot study aimed to investigate the feasibility of conducting a randomi...
Letter to the Editor: Response to Dr. Mousavi's Comments on Ogunsola et al [0.03%]
给编辑的信:回应Mousavi博士对Ogunsola等人的评论
Ayobami S Ogunsola,Samuel Smith,Eniola A Olatunji et al.
Ayobami S Ogunsola et al.