Perceptions of Marijuana Decriminalization Among Young Sexual and Gender Minorities in Chicago: An Initial Measure Validation and Test of Longitudinal Associations with Use [0.03%]
芝加哥年轻男女同性恋者对大麻非刑事化的认知：初步衡量标准的验证及与使用情况纵向关联的测试
Ethan Morgan,Christina Dyar,Christina S Hayford et al.
Ethan Morgan et al.
Background: There is a high rate of marijuana use among young sexual and gender minorities (SGM) and, as a result of recent state-level, fragmented marijuana laws, there is also likely high variability in their perceptions of marijuana decr...
Cannabidiol Treatment Results in a Common Gene Expression Response Across Aggressive Cancer Cells from Various Origins [0.03%]
大麻二酚治疗引发自不同起源的侵袭性癌细胞产生共同基因表达反应
Pierre-Yves Desprez,Ryuichi Murase,Chandani Limbad et al.
Pierre-Yves Desprez et al.
Background: We previously reported that cannabidiol (CBD), a cannabinoid with a low toxicity profile, downregulated the expression of the prometastatic gene inhibitor of DNA binding 1 (ID1) in cancer cells, leading to inhibition of tumor pr...
Morphine Induces Upregulation of Neuronally Expressed CB2 Receptors in the Spinal Dorsal Horn of Rats [0.03%]
吗啡诱导大鼠脊髓背角神经源性CB2受体表达上调
Patrick Grenier,Adam Sunavsky,Mary C Olmstead
Patrick Grenier
Background: Cannabinoid receptors play a key role in regulating numerous physiological processes, including immune function and reward signaling. Originally, endocannabinoid contributions to central nervous system processes were attributed ...
Genetic Manipulation of sn-1-Diacylglycerol Lipase and CB1 Cannabinoid Receptor Gain-of-Function Uncover Neuronal 2-Linoleoyl Glycerol Signaling in Drosophila melanogaster [0.03%]
遗传操作sn-1-二酰基甘油脂酶和CB1大麻素受体_gain-of-function_发现果蝇神经元中的2-亚油酸甘油信号转导
Giuseppe Tortoriello,Johannes Beiersdorf,Susana Romani et al.
Giuseppe Tortoriello et al.
Introduction: In mammals, sn-1-diacylglycerol lipases (DAGL) generate 2-arachidonoylglycerol (2-AG) that, as the major endocannabinoid, modulates synaptic neurotransmission by acting on CB1 cannabinoid receptors (CB1R). Even though the inse...
Natalie L Wilson,Scott N Peterson,Ronald J Ellis
Natalie L Wilson
People living with HIV infection (PWH) disclose that cannabis is an effective strategy for alleviating symptoms associated with HIV disease. However, some medical providers feel ill-informed to engage in evidence-based conversations. HIV le...
Two Decades of the International Association for Cannabinoid Medicines: 20 Years of Supporting Research and Activities Toward the Medicinal Use of Cannabis and Cannabinoids [0.03%]
国际大麻药物协会二十年：支持研究和将大麻及大麻素用于医药的两项活动二十周年纪念日
Franjo Grotenhermen,Kirsten R Müller-Vahl
Franjo Grotenhermen
Emerged from the German Association for Cannabis as Medicine (ACM), a handful of enthusiastic medical doctors from Germany, Switzerland, and Austria supported by experts from other countries established the International Association for Can...
Letter to the Editor: Ordering the Chaos in Cannabinoid-Related Research: Is it Time for a Task Force on Taxonomy? [0.03%]
致编辑的信：对大麻素相关研究进行整理：是否需要一个分类工作组的时候了？
Nicholas H B Schräder,Marieke C Bolling,André P Wolff
Nicholas H B Schräder
Renée Martin-Willett,L Cinnamon Bidwell
Renée Martin-Willett
Introduction: Policies regarding cannabis use are rapidly evolving in the United States as exemplified by the legalization of recreational use in 11 states and the District of Columbia. Previous cannabis-related laws, however, disproportion...
Prevalence of Gastrointestinal Adverse Events of Therapeutic Cannabinoids in Children: A Systematic Review and Meta-Analysis [0.03%]
治疗性大麻制剂在儿童中引起胃肠不良反应的普遍性：系统回顾和荟萃分析
Introduction: The endocannabinoid system plays a crucial role in gastrointestinal homeostasis; although some gastrointestinal adverse events have been reported with therapeutic cannabinoids in children, the complete profile of gastrointesti...