A Network Pharmacology Approach to Identify Potential Molecular Targets for Cannabidiol's Anti-Inflammatory Activity [0.03%]
运用网络药理学方法识别大麻二酚抗炎作用的潜在分子靶点
Hang Ma,Feng Xu,Chang Liu et al.
Hang Ma et al.
Introduction: Published preclinical and clinical studies support the anti-inflammatory activity of CBD, but the molecular targets (e.g., genes and proteins) that are involved in its mechanisms of action remain unclear. Herein, a network-bas...
Pauric Bannigan,James C Evans,Christine Allen
Pauric Bannigan
The global movement toward legalization of cannabis is resulting in an ever-increasing public perception that cannabis is safe. Cannabis is not the first drug to be available for nonmedical use, nor is it the first to have such an unfounded...
An Approach to Biomarker Discovery of Cannabis Use Utilizing Proteomic, Metabolomic, and Lipidomic Analyses [0.03%]
综合利用蛋白质组学、代谢组学和脂质组学分析进行大麻使用生物标志物发现的方法研究
Jesse D Hinckley,Laura Saba,Kristen Raymond et al.
Jesse D Hinckley et al.
Introduction: Relatively little is known about the molecular pathways influenced by cannabis use in humans. We used a multi-omics approach to examine protein, metabolomic, and lipid markers in plasma differentiating between cannabis users a...
A Cross-Sectional and Prospective Comparison of Medicinal Cannabis Users and Controls on Self-Reported Health [0.03%]
大麻药用价值的横断面及预期对照研究及其对自我报告健康的影响
Nicolas J Schlienz,Ryan Scalsky,Erin L Martin et al.
Nicolas J Schlienz et al.
Introduction: Despite widespread legalization, the impact of medicinal cannabis use on patient-level health and quality of life (QOL) has not been carefully evaluated. The objective of this study was to characterize self-reported demographi...
Attitudes and Beliefs Toward Cannabis Before Recreational Legalization: A Cross-Sectional Study of Community Adults in Ontario [0.03%]
娱乐大麻合法化前的社区成人 cannabis 态度和信念——一项横断面研究
Jasmine Turna,Iris Balodis,Michael Van Ameringen et al.
Jasmine Turna et al.
Objectives: To characterize attitudes and perceptions regarding risks and benefits of cannabis before Canadian legalization for recreational use, both in general and between cannabis users and nonusers. Methods: A cross-sectional sample of ...
Jawad Alzeer,Khaled Abou Hadeed,Hayriye Basar et al.
Jawad Alzeer et al.
Cannabis has been used and misused to treat many disorders. Δ9-Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the most important components of cannabis and could be used for recreational and medical purposes. The permissibility (Hala...
Jonathan Paul Liebling,Nicholas James Clarkson,Blair William Gibbs et al.
Jonathan Paul Liebling et al.
Introduction: Over-the-counter cannabidiol (CBD) products have seen unprecedented recent growth in the United Kingdom. However, analysis of these predominantly unregulated products from other countries tells us that they are often mislabele...
Contribution of Fatty Acid Amide Hydrolase to Alcohol Use Disorder: A Systematic Review [0.03%]
脂肪酸酰胺水解酶在酒精使用障碍中的作用：系统评价
Greta Niemela,Garth E Terry
Greta Niemela
Purpose: Recent research has suggested that chronic alcohol exposure induces changes in the endocannabinoid system within the central nervous system and therefore could be an attractive target for better understanding and treating alcohol u...
Kirsten Müller-Vahl
Kirsten Müller-Vahl
Self-Reported Cannabis Use and Markers of Inflammation in Men Who Have Sex With Men With and Without HIV [0.03%]
关于男男性行为者中自报的大麻使用及其与和是否感染人类免疫缺陷病毒有关的炎症标志物之间的关系的研究
Martin Krsak,Nikolas I Wada,Michael W Plankey et al.
Martin Krsak et al.
Background: Chronic inflammation contributes to aging and organ dysfunction in the general population, and is a particularly important determinant of morbidity and mortality among people with HIV (PWH). The effect of cannabis use on chronic...
Multicenter Study
Cannabis and cannabinoid research. 2021 Apr 15;6(2):165-173. DOI:10.1089/can.2019.0083 2021