A Large-Scale Naturalistic Examination of the Acute Effects of Cannabis on Pain [0.03%]
一项关于大麻急性镇痛效果的大规模自然主义考察研究
Carrie Cuttler,Emily M LaFrance,Rebecca M Craft
Carrie Cuttler
Introduction: Cannabis use for pain relief is commonly reported, yet laboratory studies and clinical trials suggest that cannabinoids are weak analgesics, and it is unclear whether perceived reductions in pain from before to after cannabis ...
Cannabinoid CB2 Receptor Activation Attenuates Fentanyl-Induced Respiratory Depression [0.03%]
大麻素CB2受体激活减弱芬太尼诱导的呼吸抑制
Carmen A Zavala,Ana C Thomaz,Vishakh Iyer et al.
Carmen A Zavala et al.
Introduction: Overdose fatalities associated with the opioid epidemic are predictably attributable to drug-induced respiratory depression. In terms of illicit opioid abuse, fentanyl is the synthetic opioid responsible for the largest number...
Frequent Cannabis Use Is Negatively Associated with Frequency of Injection Drug Use Among People Who Inject Drugs in a Canadian Setting [0.03%]
在加拿大注射吸毒者中大麻使用频率与注射毒品频率呈负相关
Hudson Reddon,Kora DeBeck,Maria-Eugenia Socias et al.
Hudson Reddon et al.
Objectives: High levels of morbidity and mortality associated with injection drug use continue to represent a significant public health challenge in many settings worldwide. Previous studies have shown an association between cannabis use an...
Scoping Review and Meta-Analysis Suggests that Cannabis Use May Reduce Cancer Risk in the United States [0.03%]
系统综述和荟萃分析认为大麻使用可能降低美国癌症风险
Thomas M Clark
Thomas M Clark
Introduction:Cannabis smoke contains carcinogens similar to tobacco, in addition to compounds with antitumor activity. Cannabis use reduces the risk of obesity and cannabinoids inhibit chronic inflammation, known causes of cancer. The net e...
In Vitro Screening of Three Commercial Cannabis-Based Products on ATP-Binding Cassette and Solute-Carrier Transporter Function [0.03%]
三种商业化大麻基产品对ATP结合盒和载体溶质载体转运功能的体外筛选研究
Lyndsey L Anderson,Maia G Etchart,Laura MacNair et al.
Lyndsey L Anderson et al.
Introduction: Legalization of medicinal cannabis around the world has led to an increase in the use of commercial cannabis-based products in the community. These cannabis-based products are being used in combination with conventional drugs ...
Effects of High-Potency Cannabis on Psychomotor Performance in Frequent Cannabis Users [0.03%]
高剂量大麻对经常使用大麻者心理运动表现的影响
Hollis C Karoly,Michael A Milburn,Ashley Brooks-Russell et al.
Hollis C Karoly et al.
Background: Recently increased access to cannabis products in the United States has been associated with increased rates of driving after cannabis use. Although numerous studies indicate that cannabis impairs psychomotor and neurocognitive ...
Evaluation of the Possible Anticonvulsant Effect of Δ9-Tetrahydrocannabinolic Acid in Murine Seizure Models [0.03%]
评估大麻素酸在小鼠癫痫模型中的潜在抗惊厥作用
Melissa J Benson,Lyndsey L Anderson,Ivan K Low et al.
Melissa J Benson et al.
Introduction: The cannabinoid Δ9-tetrahydrocannabinolic acid (Δ9-THCA) has long been suggested in review articles and anecdotal reports to be anticonvulsant; yet, there is scant evidence supporting this notion. The objective of this study...
Alexandra M Ward,Jon O Ebbert
Alexandra M Ward
Introduction: CBD is a major phytocannabinoid in hemp (Cannabis sativa containing less than 0.3% THC). Hemp cigarettes are a combustible form of hemp consisting of dried and smokable flowers, which represent 2% of the overall CBD market, an...
An Open Retrospective Study of a Standardized Cannabidiol Based-Oil in Treatment-Resistant Epilepsy [0.03%]
一项关于耐药性癫痫标准化大麻二酚油治疗的开放性回顾性研究
Francesca Marchese,Maria Stella Vari,Ganna Balagura et al.
Francesca Marchese et al.
Introduction: Cannabidiol (CBD) has antiseizure properties but no psychoactive effects. Randomized controlled trials of an oral, pharmaceutical formulation of highly purified CBD are promising; however, data regarding other formulations are...