A Multicriteria Decision Analysis Comparing Pharmacotherapy for Chronic Neuropathic Pain, Including Cannabinoids and Cannabis-Based Medical Products [0.03%]
一种多标准决策分析方法，用于比较慢性神经性疼痛的药物治疗（包括大麻素和基于大麻的医药产品）的效果
David J Nutt,Lawrence D Phillips,Michael P Barnes et al.
David J Nutt et al.
Background: Pharmacological management of chronic neuropathic pain (CNP) still represents a major clinical challenge. Collective harnessing of both the scientific evidence base and clinical experience (of clinicians and patients) can play a...
Cannabinoid Content in Cannabis Flowers and Homemade Cannabis-Based Products Used for Therapeutic Purposes in Argentina [0.03%]
阿根廷用作治疗目的的大麻花和家庭制作的大麻产品中的大麻素含量
Daniela Sedan,Cristian Vaccarini,Pablo Demetrio et al.
Daniela Sedan et al.
Introduction: A recent law (DCTO-2020-883-APN-PTE-Law No. 27,350. Regulation) passed in Argentina put an end to the ban imposed for the last 60 years on cannabis cultivation within the country. The law permits restricted access to cannabis ...
Cannabidiol-Driven Alterations to Inflammatory Protein Landscape of Lipopolysaccharide-Activated Macrophages In Vitro May Be Mediated by Autophagy and Oxidative Stress [0.03%]
大麻二酚通过自噬和氧化应激介导的对脂多糖激活的巨噬细胞促炎蛋白表达的影响
Daniel J Yeisley,Ahmad S Arabiyat,Mariah S Hahn
Daniel J Yeisley
Background: The nonpsychotropic phytocannabinoid cannabidiol (CBD) presents itself as a potentially safe and effective anti-inflammatory treatment relative to clinical standards. In this present study, we compare the capacity of CBD to the ...
Symptoms and Extraintestinal Manifestations in Active Cannabis Users with Inflammatory Bowel Disease [0.03%]
大麻活跃使用者炎症性肠病患者的症状和肠外表现
Matthew D Coates,Shannon Dalessio,Vonn Walter et al.
Matthew D Coates et al.
Introduction: Cannabis use is common in the setting of inflammatory bowel disease (IBD). Patients frequently use cannabis to treat IBD-associated symptoms, and there is evidence that cannabis and its derivatives are helpful for this purpose...
Crist N Filer
Crist N Filer
Protective Effects of Cannabidivarin and Cannabigerol on Cells of the Blood-Brain Barrier Under Ischemic Conditions [0.03%]
大麻二醇和环己基大麻酚对缺血条件下血脑屏障细胞的保护作用
Nicole L Stone,Timothy J England,Saoirse E O&#x;Sullivan
Nicole L Stone
Background and Objectives: Preclinical studies have shown cannabidiol is protective in models of ischemic stroke. Based on results from our recent systematic review, we investigated the effects of two promising neuroprotective phytocannabin...
Reducing Effect of Cannabidiol on Alcohol Self-Administration in Sardinian Alcohol-Preferring Rats [0.03%]
大麻二酚对撒丁岛喜酒大鼠饮酒行为的影响研究
Paola Maccioni,Jessica Bratzu,Mauro A M Carai et al.
Paola Maccioni et al.
Introduction: Cannabidiol (CBD) is a major cannabinoid extracted from Cannabis sativa with no abuse potential. Data from recent rodent studies suggest that amelioration of alcohol-motivated behaviors may be one of the numerous pharmacologic...
Effect of Cannabinoid 2 Receptor Modulation on the Peripheral Immune Response in Central Nervous System Injury-Induced Immunodeficiency Syndrome [0.03%]
大麻素2型受体在中枢神经系统损伤诱发的免疫缺陷综合征外周免疫反应中的作用及机制研究
Saki Sultana,Ian Burkovskiy,Juan Zhou et al.
Saki Sultana et al.
Introduction: Acute central nervous system (CNS) injury, such as stroke, spinal cord injury, or traumatic brain injury can result in dysregulated immune response, and the condition is known as CNS injury-induced immunodeficiency syndrome (C...
Recovery from Traumatic Brain Injury Following Treatment with Δ9-Tetrahydrocannabinol Is Associated with Increased Expression of Granulocyte-Colony Stimulating Factor and Other Neurotrophic Factors [0.03%]
大麻素治疗后创伤性脑损伤的恢复与粒细胞集落刺激因子和其他神经营养因子表达增加有关
Shijie Song,Xiaoyuan Kong,Bangmei Wang et al.
Shijie Song et al.
Introduction: The hematopoietic cytokine granulocyte-colony stimulating factor (G-CSF) is well known to stimulate proliferation of blood stem/progenitor cells of the leukocyte lineage, but is also recognized as a neurotrophic factor involve...
Pruntha Yoganathan,Hugh Claridge,Lucy Chester et al.
Pruntha Yoganathan et al.
Aim: To identify drug-related death trends associated with synthetic cannabinoid receptor agonists (SCRAs) reported to the National Programme on Substance Abuse Deaths (NPSAD) from England. Design: Case reports from NPSAD (England) where a ...