Are Sweet Dreams Made of These? Understanding the Relationship Between Sleep and Cannabis Use [0.03%]
sweet dreams都是这样得来的?了解睡眠和大麻使用的联系
Dalton Edwards,Francesca M Filbey
Dalton Edwards
Introduction: There is widespread literature on the interaction between cannabis use and sleep, yet the mechanisms that underlie this relationship are not well understood. Several factors lead to inconsistencies in this relationship suggest...
Diacylglycerol Lipase-β Knockout Mice Display a Sex-Dependent Attenuation of Traumatic Brain Injury-Induced Mortality with No Impact on Memory or Other Functional Consequences [0.03%]
二酰基甘油脂酶-β敲除小鼠在创伤性脑损伤致死方面表现出性别依赖的减轻,对记忆或其他功能结果无影响
Lesley D OBrien,Terry L Smith,Giulia Donvito et al.
Lesley D OBrien et al.
Background: The endogenous cannabinoid system modulates inflammatory signaling in a variety of pathological states, including traumatic brain injury (TBI). The selective expression of diacylglycerol lipase-β (DAGL-β), the 2-arachidonylgly...
Cannabis Seeds Authentication by Chloroplast and Nuclear DNA Analysis Coupled with High-Resolution Melting Method for Quality Control Purposes [0.03%]
基于高分辨率熔解法的叶绿体和核DNA分析的大麻种子鉴定质量控制方法研究
Leonardo Anabalón,Jaime Solano,Francisco Encina-Montoya et al.
Leonardo Anabalón et al.
Background: Cannabis plants and their seed have been used in many cultures as a source of medicine and feeding during history. Today, there is an increasing demand for cannabis seeds for medical use. Moreover, a seed sales market with no le...
Health Claims About Cannabidiol Products: A Retrospective Analysis of U.S. Food and Drug Administration Warning Letters from 2015 to 2019 [0.03%]
美国食品药品监督管理局关于大麻二酚产品的警告信中的健康声明回顾性分析(2015-2019)
Kimberly G Wagoner,Allison J Lazard,E Alfonso Romero-Sandoval et al.
Kimberly G Wagoner et al.
Background: Cannabidiol (CBD) products are increasingly available to consumers in the United States and are subject to regulation by the U.S. Food and Drug Administration (FDA). CBD products cannot be marketed as unapproved new drugs with c...
Therapeutic Potential of Cannabidiol, Cannabidiolic Acid, and Cannabidiolic Acid Methyl Ester as Treatments for Nausea and Vomiting [0.03%]
大麻二酚、大麻二酚酸和大麻二酚甲酯治疗恶心呕吐的潜力
Erin M Rock,Cheryl L Limebeer,Roger G Pertwee et al.
Erin M Rock et al.
Introduction: Nausea and vomiting are the most distressing symptoms reported by oncology patients undergoing anticancer treatment. With the currently available treatments, vomiting and especially nausea remain problematic, highlighting the ...
Modulatory Potential of Cannabidiol on the Opioid-Induced Inflammatory Response [0.03%]
cannabidiol调节阿片类引起的炎症反应的潜力
Clare T Johnson,Heather B Bradshaw
Clare T Johnson
Opioids are effective analgesics; however, there are many negative consequences of chronic use. One important side effect of chronic opioid use is the continuous engagement of the immune response that can exacerbate chronic pain. The opioid...
Kinetics of CBD, Δ9-THC Degradation and Cannabinol Formation in Cannabis Resin at Various Temperature and pH Conditions [0.03%]
大麻树脂中CBD、Δ9-THC降解及 cannabinol生成的动力学研究不同的温度和pH条件下的问题
Wuttichai Jaidee,Ittipon Siridechakorn,Siwames Nessopa et al.
Wuttichai Jaidee et al.
Introduction: Cannabidiol (CBD), cannabinol (CBN), and Δ9-tetrahydrocannabinol (Δ9-THC) are major cannabinoids in cannabis resin and products. The kinetic of the chemical reaction of resin cannabis is important for product development and...
Cannabis Varieties Can Be Distinguished by Achene Shape Using Geometric Morphometrics [0.03%]
运用几何形态计量法通过外形区分大麻品种
Federico Márquez,Mariana Lozada,Yanina L Idaszkin et al.
Federico Márquez et al.
Introduction: Cannabis plant uses are widespread across human cultures. The current tendency is to classify Cannabis varieties into chemovars upon their chemical fingerprint, mainly cannabinoids and terpenoids content. The identification of...
Monoacylglycerol Lipase Inhibition Using JZL184 Attenuates Paw Inflammation and Functional Deficits in a Mouse Model of Inflammatory Arthritis [0.03%]
应用JZL184抑制单酰基甘油脂酶减轻类风湿关节炎小鼠模型足部炎症和功能缺损
Sara R Nass,Floyd F Steele,Timothy B Ware et al.
Sara R Nass et al.
Background: Patients with rheumatoid arthritis (RA) experience joint swelling and cartilage destruction resulting in chronic pain, functional disability, and compromised joint function. Current RA treatments, including glucocorticoid recept...
Real-Time Imaging of Immune Modulation by Cannabinoids Using Intravital Fluorescence Microscopy [0.03%]
实时成像技术在体内荧光显微镜下使用大麻素免疫调节的实时成像
Juan Zhou,Kiyana Kamali,J Daniel Lafreniere et al.
Juan Zhou et al.
Introduction: The endocannabinoid system (ECS) is an endogenous regulatory system involved in a wide range of physiologic and disease processes. Study of ECS regulation provides novel drug targets for disease treatment. Intravital microscop...