Can Endocannabinoids Explain CBD-Mediated Reduction in Blood Pressure? Insights from a Randomized, Placebo-Controlled, Crossover Trial [0.03%]
内源性大麻素能解释CBD介导的血压降低现象吗？一项随机、安慰剂对照、交叉试验的新见解
Marko Kumric,Goran Dujic,Josip Vrdoljak et al.
Marko Kumric et al.
Background: HYPER-H21-4 trial, a randomized, placebo-controlled, crossover trial, showed that chronic cannabidiol (CBD) supplementation reduces blood pressure (BP) in patients with primary hypertension. Given the association between the end...
Effects of Voluntary Ingestion of Synthetic Delta-9-Tetrahydrocannabinol on the Hedonic Value of Rewarding and Aversive Substances and CB1 Receptor Expression [0.03%]
合成Δ-9-四氢大麻酚的自愿摄入对愉悦物质和厌恶物质的欣快价值及CB1受体表达的影响
Dylan A Laux,Mary E Cain
Dylan A Laux
Background: Human studies indicate a relationship between delta-9-tetrahydrocannabinol (THC) and alcohol use, yet research on their codependency remains limited. Rodent models have shown that cannabinoids can enhance the incentive salience ...
Short-Term Low Dose Cannabidiol Does Not Influence Glucose Tolerance or the Gut Microbiome in Sedentary Adults with Overweight and Obesity: Pilot Study [0.03%]
大麻二酚短期低剂量不会影响久坐不动的超重和肥胖成年人的葡萄糖耐量或肠道菌群：试点研究
Taylor R Ewell,Matthew C Bomar,Kieran S S Abbotts et al.
Taylor R Ewell et al.
Introduction: Epidemiological data indicate that regular users of cannabis products may be protected from type 2 diabetes, although the mechanism is not understood. Observations from animal studies suggest that the cannabinoid, cannabidiol ...
Sexually Dimorphic Effects of a Single Neonatal Δ9-tetrahydrocannabinol Exposure on Neuronal Dendritic Morphology and Cognitive Functions in Rats [0.03%]
单一新生期Δ9-四氢大麻酚暴露对成年大鼠海马区树突形态及认知功能的性别差异效应研究
Meetu Wadhwa,Gregory A Chinn,Katrina Duong et al.
Meetu Wadhwa et al.
Background: Cannabis consumption among adults, including pregnant and breastfeeding women, continues to rise. However, the long-term effects of early-life exposure to cannabinoids on brain development remain unclear. Δ9-tetrahydrocannabino...
Cannabis Use During Pregnancy Is Associated with the Suppression of Circulating Maternal Cytokines [0.03%]
孕期使用大麻与循环母体细胞因子的抑制有关
Omayma Alshaarawy,Morgan Sotzen,Emily Kurjan et al.
Omayma Alshaarawy et al.
Introduction: The prevalence of prenatal cannabis use has nearly doubled in the United States. Cannabinoid 2 receptors are predominately expressed in cells of the human immune system, and delta-9 tetrahydrocannabinol (THC), the primary acti...
Crist N Filer
Crist N Filer
Stress Responsivity of Endocannabinoids and Related Biomolecules in Plasma and Saliva [0.03%]
血浆和唾液中内源性大麻素及相关生物分子的应激反应性
Jessica Hargreaves,Madeline Jarvis,Khalisa Amir Hamzah et al.
Jessica Hargreaves et al.
Introduction: The endocannabinoid system regulates numerous physiological functions, including the stress response, and is frequently implicated in stress-related disorders. Understanding how this system is altered during stress is therefor...
Taking Care of Themselves: Cannabis Use Among Informal Care Partners of Older Adults [0.03%]
照顾自己：老年家庭成员的大麻使用情况
Brian Kaskie,Fadi Martinos,Divya Bhagianadh et al.
Brian Kaskie et al.
Background: Cannabis use among older persons has been increasing relative to younger populations, and persons over 50 years old are more likely to use cannabis for age-related therapeutic purposes. We suspected that spouses, adult children,...
Effects of Different Cannabinoid Formulations on Anxiety-Related Disorders, and Tourette Syndrome: A Systematic Review and Meta-Analysis [0.03%]
大麻素制剂对焦虑相关障碍和抽动秽语综合征影响的系统评价和.meta.分析
Adrieli Oliveira Raminelli,João Luís Q Simei,Francisco S Guimarães et al.
Adrieli Oliveira Raminelli et al.
Introduction: Cannabinoid formulations have been increasingly proposed as therapeutic potential options for anxiety disorders (ADs). Several countries have expanded regulatory frameworks facilitating access to these compounds due to their a...
Influence of Carrier Oil, Sex, and Age on Pharmacokinetic and Acute Behavioral Effects of Vaporized Cannabis Extract in Mice [0.03%]
载体油、性别和年龄对小鼠蒸气化大麻提取物药代动力学和急性行为的影响
Sara R Westbrook,Allison L Jensen,Vanessa Copeland-Solorzano et al.
Sara R Westbrook et al.
The legalization of cannabis in several states across the United States has increased the need to better understand its effects on the body, brain, and behavior, particularly in different populations. Previous rodent studies have revealed a...