Unveiling Neurological Benefits: A Review of Hemp Leaf, Flower, Seed Oil Extract, and Their Phytochemical Properties in Neurological Disorders [0.03%]
揭开神经益处的面纱:大麻叶、花、种子油提取物及其植物化学性质在神经系统疾病中的综述
Atchuthan Purushothaman,Anju Krishnan
Atchuthan Purushothaman
Neurological disorders such as epilepsy, Alzheimer's disease, Parkinson's disease, and multiple sclerosis present significant global health care challenges, with complex pathophysiology and limited therapeutic options that often carry subst...
Administration of the Synthetic Cannabinoid WIN55,212-2 Increases BDNF Expression Levels in the Adolescent Rat Brain [0.03%]
合成大麻素WIN55212-2调节青春期大鼠脑源性神经营养因子表达水平
Alejandro Guadalupe Torres,Jordan Santos,Dolores Vazquez Sanroman
Alejandro Guadalupe Torres
Background: The increase in cannabinoid use among adolescents has become a public health concern in North America, with more than one-third of 12th graders in the United States reporting consumption of some form of cannabis within the past ...
Early Life Exposure to Δ9-Tetrahydrocannabinol Causes Persistent Growth, Behavior, and Bioenergetic Outcomes in Zebrafish [0.03%]
早期暴露于Δ9-四氢大麻酚会导致斑马鱼持久的生长、行为和生物能量代谢结果
Zacharias Pandelides,Cammi Thornton,Jason J Paris et al.
Zacharias Pandelides et al.
Introduction: Although classified in the United States as Schedule I drugs, medical and recreational cannabis and Δ9-tetrahydrocannabinol (THC) are becoming increasingly consumed by pregnant women. Determining the potential adverse effects...
Cannabis Use in Older Individuals May Be an Important and Under-Recognized Risk Factor for Motor Vehicle Crashes [0.03%]
老年人使用大麻可能是被低估的机动车事故的重要风险因素
Godfrey D Pearlson,Deepak C DSouza,Richard A Marottoli et al.
Godfrey D Pearlson et al.
There is a large and growing population of individuals aged over 65 in the United States, many of whom drive automobiles. Elements of aging may adversely impact driving ability; in some individuals, mild cognitive impairment and early demen...
A Randomized, Open-Label Trial to Assess Feasibility and Tolerability of Topical Cannabis Balms for the Treatment of Aromatase Inhibitor-Associated Musculoskeletal Syndrome (AIMSS) [0.03%]
评估大麻药膏治疗芳香化酶抑制剂相关肌骨系统综合征(AIMSS)可行性和耐受性的随机开放标签试验
Dylan Zylla,Dame Idossa,Maria Borrero et al.
Dylan Zylla et al.
Introduction: Aromatase inhibitors (AIs) are commonly used for postmenopausal women with hormone receptor-positive breast cancer. Nearly two-thirds of women on AIs have arthralgias, joint stiffness, and/or bone pains referred to as aromatas...
Using Chemical Ecology as a Guide for Development and Differentiation of Clinically Relevant Phytochemical Profiles in Cannabis Trichome [0.03%]
以化学生态学为指导开发和分化临床相关的大麻化学成分谱系
Michael Tims,John Courie,Joseph M Betz
Michael Tims
This article examines the effects of biotic and abiotic influences on trichome development in cannabis and how these influences may shape the ultimate cannabinoid and terpene profiles in cannabis cultivars. As cannabis agriculture focuses p...
Emerging Hemp-Derived Semi-Synthetic Cannabinoids, Absent Regulations: Patterns of Use and Adverse Effects Among a Sample of U.S. Cannabis Consumers [0.03%]
一种新兴的麻类半合成大麻衍生物(缺乏管制):在美国 cannabis 消费者样本中的使用模式和不良反应
Elisa Pabon,Stephanie Lake,Conor H Murray et al.
Elisa Pabon et al.
Introduction: Hemp-derived semi-synthetic cannabinoids are marketed as legal alternatives to cannabis containing ≥0.3% Δ9-tetrahydrocannabinol (THC) but remain unregulated at the federal and state levels. Their growing availability unders...
Tolerance but No Spontaneous Withdrawal Following Repeated THC Injections in Male and Female Rats [0.03%]
重复四氢大麻酚注射后雄性和雌性大鼠的耐受性和非自发撤药现象
Christa M Hickey,Casey Poling,Wyatt Grimes et al.
Christa M Hickey et al.
Introduction: Tolerance and dependence are known to occur with prolonged cannabis use. Few animal experiments on spontaneous withdrawal from delta-9-tetrahydrocannabinol (THC), the primary psychoactive compound in cannabis, have been conduc...
Alcohol-Induced Dilation of Fetal Cerebral Arteries Is Region-Specific and Mediated by Cannabinoid Receptor 1 in a Sexually Dimorphic Manner [0.03%]
酒精通过性二倍体方式特异性地激活 cannabinoid 受体 1 而导致胎儿脑动脉扩张
Shiwani Thapa,Elizabeth H Schneider,Steven C Mysiewicz et al.
Shiwani Thapa et al.
Introduction: Prenatal alcohol exposure (PAE) is a leading cause of birth defects and developmental impairments, resulting in a spectrum of disorders ranging from mild to severe, which are termed fetal alcohol spectrum disorders (FASD). Glo...
Deepak Cyril DSouza,Prakash Gupta,Ashley M Schnakenberg Martin et al.
Deepak Cyril DSouza et al.