When Public Will Meets Legislative Resistance: Five Lessons from Ohio's Issue 2 Cannabis Legalization Controversy [0.03%]
当公众意愿遭遇立法阻力时：俄亥俄州第2号议案大麻合法化争议的五点启示
Bryant M Stone
Bryant M Stone
In this paper, I explore the challenges of legalizing cannabis in Ohio, focusing on the passing of the Issue 2 Bill, legislative resistance, and public response. I propose five strategies for effective policy change: persistent advocacy pos...
Does the Quantification of Δ9-Tetrahydrocannabinolic Acid A in Serum/Plasma Provide Any Additional Information About Consumption Pattern from Drivers Under the Influence of Cannabis? [0.03%]
血液中药物代谢产物Δ9-四氢大麻酚酸A的定量测定能否为执法人员提供更多涉毒驾驶者的大麻摄入模式信息？
Lisa Höfert,Sven Baumann,Jan Dreßler et al.
Lisa Höfert et al.
Introduction: Δ9-tetrahydrocannabinolic acid A (THCA-A) is one of the main ingredients of cannabis plants and is converted to the psychoactive substance Δ9-tetrahydrocannabinol (THC) by decarboxylation during heating above ∼90°C. During...
Electrophysiological Phenotypes of Hippocampal Synaptic and Network Functions in Cannabinoid Receptor 2 Knockout Mice [0.03%]
cannabinoid receptor 2基因敲除小鼠海马突触和神经网络的电生理表型分析
Shuangtao Li,Yongchang He,Dharshaun Turner et al.
Shuangtao Li et al.
Background: The cannabinoid receptor 2 (CB2R), a cannabinoid receptor primarily expressed in immune cells, has been found in the brain, particularly in the hippocampus, where it plays crucial roles in modulating various neural functions, in...
Impact of Early-Life Adversity on Cannabis Use: Exploring the Mediating and Moderating Effects of Chronic Pain [0.03%]
早期逆境对大麻使用的影响：探讨慢性疼痛的中介和调节作用
James S Hodges,Briana N DeAngelis,Jacob Borodovsky et al.
James S Hodges et al.
Background: Although research suggests that early-life adversity (ELA) and cannabis use are linked, researchers have not established factors that mediate or modify this relationship. Identifying such factors could help in developing targete...
Cannabis Dependence is Associated with Reduced Hippocampal Subregion Volumes Independently of Sex: Findings from an ENIGMA Addiction Working Group Multi-Country Study [0.03%]
基于性别的一项跨国研究发现：大麻依赖与海马亚区体积减少有关——来自ENIGMA成瘾工作组的一项研究结果
Valentina Lorenzetti,Alexandra Gaillard,Eugene McTavish et al.
Valentina Lorenzetti et al.
Background: Males and females who consume cannabis can experience different mental health and cognitive problems. Neuroscientific theories of addiction postulate that dependence is underscored by neuroadaptations, but do not account for the...
Cannabinoid Receptor 2 Gene Polymorphism and the Risk of Developing Rheumatoid Arthritis in Lebanese Patients [0.03%]
卡巴胆碱受体基因多态性与黎巴嫩类风湿关节炎患者的发病风险关系研究
Morouj Ismail,Ghada Khawaja
Morouj Ismail
Objective: Evidence supports a role of cannabinoid receptor 2 (CB2) in regulating the immune response. Some variations in the CB2 receptor gene (CB2) were linked to the susceptibility of developing rheumatoid arthritis (RA). The aim of this...
Re: "Assessing Cannabis Use in People with Psychosis" by Chesney et al [0.03%]
《评估精神病患者的大麻使用情况》由Chesney等人撰写回复
Yann Barguil,Laura Chiaradia,Guy A Southwell et al.
Yann Barguil et al.
Perception of Risk of Harm from Cannabis Use Among Women of Reproductive Age with Disabilities [0.03%]
具有生育能力的残疾妇女对使用大麻造成危害的风险的认知
Panagiota Kitsantas,Salman M Aljoudi,Lea Sacca
Panagiota Kitsantas
Objectives: To examine perceived risk of harm from weekly cannabis use among reproductive-aged women with disabilities. Methods: Using data from the 2021 National Survey on Drug Use and Health, we assessed perceived risk of harm associated ...
Clinical Application of Cannabis Vaporization: Examining Safety and Best Practices [0.03%]
大麻蒸汽吸入的临床应用：检测安全性和最佳实践
Caroline A MacCallum,Lindsay A Lo,Michael Boivin
Caroline A MacCallum
Introduction: Cannabis vaporization is useful for individuals requiring fast-acting method of cannabis administration and for individuals using smoked cannabis as a harm reduction tool. There is a need for guidance on how to assess if a pat...
Acute Effects of Monoacylglycerol Lipase Inhibitor ABX1431 on Neuronal Hyperexcitability, Nociception, Locomotion, and the Endocannabinoid System in HIV-1 Tat Male Mice [0.03%]
HIV-1 Tat男性小鼠神经元过度兴奋，nociception，运动和内源性大麻素系统的单酰甘油脂肪酶抑制剂ABX1431的急性效应
Barkha J Yadav-Samudrala,Havilah P Ravula,Karenna M Barmada et al.
Barkha J Yadav-Samudrala et al.
Background: Evidence suggests that monoacylglycerol lipase (MAGL) inhibitors can potentially treat HIV symptoms by increasing the concentration of 2-arachidonoylglycerol (2-AG). We examined a selective MAGL inhibitor ABX1431 in the context ...