Emerging Hemp-Derived Semi-Synthetic Cannabinoids, Absent Regulations: Patterns of Use and Adverse Effects Among a Sample of U.S. Cannabis Consumers [0.03%]
一种新兴的麻类半合成大麻衍生物（缺乏管制）：在美国 cannabis 消费者样本中的使用模式和不良反应
Elisa Pabon,Stephanie Lake,Conor H Murray et al.
Elisa Pabon et al.
Introduction: Hemp-derived semi-synthetic cannabinoids are marketed as legal alternatives to cannabis containing ≥0.3% Δ9-tetrahydrocannabinol (THC) but remain unregulated at the federal and state levels. Their growing availability unders...
Tolerance but No Spontaneous Withdrawal Following Repeated THC Injections in Male and Female Rats [0.03%]
重复四氢大麻酚注射后雄性和雌性大鼠的耐受性和非自发撤药现象
Christa M Hickey,Casey Poling,Wyatt Grimes et al.
Christa M Hickey et al.
Introduction: Tolerance and dependence are known to occur with prolonged cannabis use. Few animal experiments on spontaneous withdrawal from delta-9-tetrahydrocannabinol (THC), the primary psychoactive compound in cannabis, have been conduc...
Alcohol-Induced Dilation of Fetal Cerebral Arteries Is Region-Specific and Mediated by Cannabinoid Receptor 1 in a Sexually Dimorphic Manner [0.03%]
酒精通过性二倍体方式特异性地激活 cannabinoid 受体 1 而导致胎儿脑动脉扩张
Shiwani Thapa,Elizabeth H Schneider,Steven C Mysiewicz et al.
Shiwani Thapa et al.
Introduction: Prenatal alcohol exposure (PAE) is a leading cause of birth defects and developmental impairments, resulting in a spectrum of disorders ranging from mild to severe, which are termed fetal alcohol spectrum disorders (FASD). Glo...
Deepak Cyril D&#x;Souza,Prakash Gupta,Ashley M Schnakenberg Martin et al.
Deepak Cyril D&#x;Souza et al.
Can Endocannabinoids Explain CBD-Mediated Reduction in Blood Pressure? Insights from a Randomized, Placebo-Controlled, Crossover Trial [0.03%]
内源性大麻素能解释CBD介导的血压降低现象吗？一项随机、安慰剂对照、交叉试验的新见解
Marko Kumric,Goran Dujic,Josip Vrdoljak et al.
Marko Kumric et al.
Background: HYPER-H21-4 trial, a randomized, placebo-controlled, crossover trial, showed that chronic cannabidiol (CBD) supplementation reduces blood pressure (BP) in patients with primary hypertension. Given the association between the end...
Effects of Voluntary Ingestion of Synthetic Delta-9-Tetrahydrocannabinol on the Hedonic Value of Rewarding and Aversive Substances and CB1 Receptor Expression [0.03%]
合成Δ-9-四氢大麻酚的自愿摄入对愉悦物质和厌恶物质的欣快价值及CB1受体表达的影响
Dylan A Laux,Mary E Cain
Dylan A Laux
Background: Human studies indicate a relationship between delta-9-tetrahydrocannabinol (THC) and alcohol use, yet research on their codependency remains limited. Rodent models have shown that cannabinoids can enhance the incentive salience ...
Short-Term Low Dose Cannabidiol Does Not Influence Glucose Tolerance or the Gut Microbiome in Sedentary Adults with Overweight and Obesity: Pilot Study [0.03%]
大麻二酚短期低剂量不会影响久坐不动的超重和肥胖成年人的葡萄糖耐量或肠道菌群：试点研究
Taylor R Ewell,Matthew C Bomar,Kieran S S Abbotts et al.
Taylor R Ewell et al.
Introduction: Epidemiological data indicate that regular users of cannabis products may be protected from type 2 diabetes, although the mechanism is not understood. Observations from animal studies suggest that the cannabinoid, cannabidiol ...
Sexually Dimorphic Effects of a Single Neonatal Δ9-tetrahydrocannabinol Exposure on Neuronal Dendritic Morphology and Cognitive Functions in Rats [0.03%]
单一新生期Δ9-四氢大麻酚暴露对成年大鼠海马区树突形态及认知功能的性别差异效应研究
Meetu Wadhwa,Gregory A Chinn,Katrina Duong et al.
Meetu Wadhwa et al.
Background: Cannabis consumption among adults, including pregnant and breastfeeding women, continues to rise. However, the long-term effects of early-life exposure to cannabinoids on brain development remain unclear. Δ9-tetrahydrocannabino...
Cannabis Use During Pregnancy Is Associated with the Suppression of Circulating Maternal Cytokines [0.03%]
孕期使用大麻与循环母体细胞因子的抑制有关
Omayma Alshaarawy,Morgan Sotzen,Emily Kurjan et al.
Omayma Alshaarawy et al.
Introduction: The prevalence of prenatal cannabis use has nearly doubled in the United States. Cannabinoid 2 receptors are predominately expressed in cells of the human immune system, and delta-9 tetrahydrocannabinol (THC), the primary acti...
Crist N Filer
Crist N Filer