Capivasertib cost-effectiveness in treating advanced breast cancer: A US health care perspective [0.03%]
capivasertib治疗晚期乳腺癌的成本效益分析(美国卫生保健体系角度)
Chijioke Okeke,Javeria Khalid,J Douglas Thornton et al.
Chijioke Okeke et al.
Background: Capivasertib has gained US Food and Drug Administration approval in combination with a hormonal-based regimen (eg, fulvestrant) for managing hormone receptor-positive (HR+) and human epidermal growth factor re...
Addressing complexity: The development and pilot testing of a user-friendly Medicare Part D patient decision aid tool [0.03%]
应对复杂性:简易 Medicare 第一部分 D 项患者决策辅助工具的开发与试点测试
Devika A Shenoy,Abigail VanLonkhuyzen,Bradley Q Fox et al.
Devika A Shenoy et al.
Background: Selecting a Medicare Part D prescription drug plan can be challenging because of limited health insurance literacy and complex plan features. Existing online tools, such as the Medicare Plan Finder (MPF), ofte...
Impact of empirical treatment failure on health care resource utilization and costs among female patients with uncomplicated urinary tract infections in a US-based Integrated Health Delivery Network [0.03%]
美国综合医疗服务网络中经验性治疗失败对单纯性尿路感染女性患者医疗资源利用和费用的影响分析
Jeffrey J Ellis,Anushree Iyengar,Hari Bandi et al.
Jeffrey J Ellis et al.
Background: Uncomplicated urinary tract infections (uUTIs) are one of the most common outpatient infections in the United States. Despite this, there are limited data on the impact of oral antibiotic treatment failure (TF...
Impact of a real-time prescription benefit on adherence and utilization of low-cost prescription alternatives for members new to diabetes treatment [0.03%]
实时处方福利对新诊断糖尿病患者低成本处方药依从性和利用度的影响
Elizabeth C S Swart,Jennifer L Nguyen,Samuel K Peasah et al.
Elizabeth C S Swart et al.
Background: Chronic diseases such as diabetes are a major burden to the US health care system. High medication adherence helps improve diabetes outcomes and reduce cost. Cost of medications can contribute to nonadherence....
Current landscape of US Food and Drug Administration use of expedited regulatory approvals for colorectal cancer care [0.03%]
美国食品药品监督管理局加速审批在结直肠癌治疗中的应用现状分析
Danea M Horn,Mireille Jacobson,Kathryn A Phillips
Danea M Horn
Background: US Food and Drug Administration (FDA) expedited regulatory pathways (ERPs) accelerate the availability of drugs and diagnostic tests for severe conditions and fill unmet medical needs. ERPs accelerate access t...
Cost-related barriers to medication use among diverse participants with obesity-associated asthma [0.03%]
肥胖相关哮喘患者因费用而产生的用药障碍——一项针对不同族裔人群的研究
Luyu Xie,Joohan Kim,Jaime P Almandoz et al.
Luyu Xie et al.
Background: Individuals with obesity-associated asthma (OAA) have worse health outcomes than those with asthma and healthy weight (no OAA). The impact of cost barriers on medication use and how it varies by racial and eth...
Real-world costs, treatment patterns, and clinical outcomes associated with treatments for advanced anaplastic lymphoma kinase-positive non-small cell lung cancer [0.03%]
ALK阳性晚期非小细胞肺癌治疗的现实世界成本、治疗模式和临床结果
Rahul Mudumba,Xiaofan Liu,Ian Davis et al.
Rahul Mudumba et al.
Background: Alectinib, brigatinib, and lorlatinib are all preferred first-line (1L) therapies for anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) in National Comprehensive Cancer Network (NCCN...
AMCP Market Insights: Payer best practices for timely diagnosis and optimal management of idiopathic hypersomnia [0.03%]
AMCP市场洞察:及时诊断和合理管理特发性过度嗜睡的付款方最佳实践
Bridget Flavin,Denise Wolff,Zachary Contreras et al.
Bridget Flavin et al.
Idiopathic hypersomnia (IH) is a chronic, neurologic disorder with a primary symptom of excessive daytime sleepiness. There are challenges to timely, accurate diagnosis of IH and, therefore, to optimal management. To better understand these...
Changes in urine albumin-to-creatinine ratio and health care resource utilization and costs in patients with type 2 diabetes and chronic kidney disease [0.03%]
尿白蛋白肌酐比值变化与2型糖尿病伴慢性肾脏病患者的医疗资源利用及费用的关系
Kevin M Pantalone,Rakesh Singh,Aozhou Wu et al.
Kevin M Pantalone et al.
Background: Albuminuria, indicated by an elevated urine albumin-to-creatinine ratio (UACR) at baseline, is consistently associated with poor clinical outcomes and increased economic burden. The effect of a change in album...
A structured approach for identifying disease analogs for pulmonary arterial hypertension [0.03%]
肺动脉高压疾病类推的识别方法学研究
Karim El-Kersh,Nadine Zawadzki,Anna Watzker et al.
Karim El-Kersh et al.
Drug manufacturers often use disease analogs to describe diseases-particularly rare diseases-to payers, policymakers, and stakeholders. However, these comparisons are typically anecdotal. We propose a 4-step, systematic approach to identify...