A Cost-Effectiveness Analysis for Avelumab as a First-Line Maintenance Treatment of Advanced Urothelial Carcinoma in the Netherlands [0.03%]
阿维鲁单抗维持治疗晚期尿路上皮癌的 cost-effectiveness 分析
David Smalbrugge,Tim Walsteijn,Jeantine de Feijter et al.
David Smalbrugge et al.
Introduction: Advanced or metastatic urothelial carcinoma (UC) is an incurable disease with a high disease burden and a poor prognosis. Avelumab as first-line (1L) maintenance treatment is an innovative therapy option for...
Phase I Study of Sorafenib Combined with Gemcitabine and Carboplatin in Patients with Advanced Solid Tumors [0.03%]
索拉非尼联合吉西他滨和卡铂治疗晚期恶性实体瘤的I期临床研究
Daphne W M Voogd,Merel J J Lucassen,Ruud van der Noll et al.
Daphne W M Voogd et al.
Introduction: A combination of targeted anticancer drugs with cytotoxic therapy can potentially overcome multidrug resistance. The multi-target kinase inhibitor sorafenib demonstrates synergistic activity when combined wi...
Increasing Awareness of Soft-Tissue Sarcoma: Podcast of a Patient-HCP Discussion [0.03%]
提高软组织肉瘤意识：患者与医护提供者讨论的播客
Gillian Faskin,Sam Hackett
Gillian Faskin
Soft-tissue sarcoma is a rare cancer, making up less than 1% of new cancer diagnoses. They comprise tumours of the connective tissue, and as such can arise in any part of the body and can mimic other conditions. In addition, there are over ...
Bone Metastases and Skeletal Complications: Information and Involvement of Patients with Cancer in the Treatment Pathway [0.03%]
骨转移和骨骼并发症：癌症患者参与治疗流程的信息和作用
Stefania Gori,Alessandra Fabi,Giuseppe Procopio et al.
Stefania Gori et al.
Introduction: Adequate information about patients with bone metastases could increase adherence to treatment and reduce or delay skeletal and dental complications. Limited data are available on patient awareness, the degr...
Survey of Health Care Providers on Social Determinants of Health and Treatment Decision-Making for Patients With HR+/HER2- Metastatic Breast Cancer [0.03%]
关于健康护理提供者就社会决定因素对HR+/HER2-转移性乳腺癌患者的治疗决策影响的调查报告
Monique Gary,Editha Krueger,Molly Kisiel et al.
Monique Gary et al.
Introduction: Social determinants of health (SDOH) are a range of nonmedical factors that contribute to outcome disparities among certain groups of patients; however, little is known about how SDOH affect treatment decisi...
Promising Drugs Targeting Specific Mechanisms of Deregulation in T Cell Lineage Acute Lymphoblastic Leukemia [0.03%]
针对T细胞急性淋巴细胞白血病异常调控的特定机制的有前景的药物
Xavier Thomas
Xavier Thomas
T cell acute lymphoblastic leukemia (T-ALL) is a class of hematological malignancies predominantly affecting children, adolescents, and young adults, marked by aggressive behavior and poor clinical response, especially in relapsing cases. A...
On the Horizon: A Global Multidisciplinary Perspective on Delivering Emerging Therapies for Patients with BCG-Naïve High-Risk NMIBC [0.03%]
未来展望：全球多学科视角下BCG无效高危非肌层浸润性膀胱癌新兴疗法的临床应用挑战与机遇
Bernadett E Szabados,Félix Guerrero-Ramos,Enrique Grande et al.
Bernadett E Szabados et al.
Patients with high-risk non-muscle invasive bladder cancer (NMIBC) are generally treated with transurethral resection of the bladder tumor followed by intravesical bacillus Calmette-Guérin (BCG), the current standard of care. However, recu...
Oncotype DX Recurrence Score and Germline BRCA Variants in Patients with HR-Positive/HER2-Negative Early Breast Cancer: A Retrospective Observational Study [0.03%]
HR阳性/HER2阴性早期乳腺癌患者中OncoType DX复发评分与胚系BRCA变异：回顾性观察研究
Stefania Morganti,Rabia A Khan,Luis C Berrocal-Almanza et al.
Stefania Morganti et al.
Introduction: The Oncotype DX (ODX) recurrence score (RS) is prognostic and predictive of chemotherapy benefit in patients with hormone receptor (HR)-positive/human epidermal growth factor receptor 2 (HER2)-negative early...
Understanding Patients' Experiences in Newly Diagnosed Adult B Cell Acute Lymphoblastic Leukemia: Qualitative Interviews to Develop a Patient-Centric Conceptual Model [0.03%]
成人新诊断的B细胞急性淋巴细胞白血病患者的治疗体验：定性访谈建立以患者为中心的概念模型
Michael Chladek,Maria Virginia Meza,Jessie Wang et al.
Michael Chladek et al.
Introduction: Treatment outcomes for older adults with B cell acute lymphoblastic leukemia (B cell ALL) are poor, partially because of poor tolerance to intense chemotherapy. Information on patient experience-an important...
Clinical and Dosimetric Predictors of Early Onset Postradiation Hypothyroidism in Patients with Head and Neck Malignancies: A Logistic Regression Analysis [0.03%]
头颈部恶性肿瘤患者放射治疗后早期甲状腺功能减退的临床及剂量预测因素： logistic回归分析
Ahmad Ameri,Zohreh Azma,Khashayar Fattah et al.
Ahmad Ameri et al.
Introduction: Hypothyroidism commonly occurs as a side effect following radiotherapy for head and neck malignancies, yet limited information exists to predict the risk of postradiation hypothyroidism. This study aims to i...