Interdisciplinary therapy of extremity soft tissue sarcomas: current evidence on systemic treatments and the role of reconstructive surgery [0.03%]
四肢软组织肉瘤的综合治疗：系统性治疗和重建手术作用的当前证据
Yonca Steubing,Christoph Wallner,Marcus Lehnhardt et al.
Yonca Steubing et al.
Objectives: Soft tissue sarcomas are rare and heterogenous tumors, that often pose diagnostic and therapeutic challenges. Guideline-compliant therapy includes surgical resection with negative margins, supplementary radiot...
Justus P Beier,Frank Hildebrand
Justus P Beier
Luca Kümmerl,Theresa Promny,Elisabeth Eschenbacher et al.
Luca Kümmerl et al.
Objectives: This study examines the clinical application of interdisciplinary reconstructive strategies for complex forearm and hand defects. Emphasis is placed on principles guiding flap selection, anatomical localizatio...
Interdisciplinary lower extremity reconstruction in peripheral artery disease with AV-loops and latissimus dorsi flaps [0.03%]
外周动脉疾病膝下缺损的复合组织移植修复术
Simon Reß,Anja M Boos,Alexander Gombert et al.
Simon Reß et al.
Objectives: Extensive soft tissue defects of the lower leg can be effectively addressed by transplantation of various free microvascular flaps. A fundamental requirement for successful free microvascular flap coverage is ...
Combined inhibition of the complement component C5 and the TLR-coreceptor CD14 alters the posttraumatic response in fracture hematoma in a porcine polytrauma model [0.03%]
补体成分C5和TLR核心受体CD14联合抑制改变猪多发伤模型骨折血肿的创伤反应
Dong Chen,Jasper Nies,Klemens Horst et al.
Dong Chen et al.
Objectives: Polytrauma is characterized by high mortality and morbidity rates, partly due to the post-traumatic immune response. This follow-up study investigated the effect of combined inhibition of complement factor 5 (...
Strategies for surgical reconstruction of complex elbow deformities based on patient-specific instruments - a case series and narrative review [0.03%]
基于患者特定仪器的复杂肘部畸形外科重建策略——病例系列和叙述性回顾
Sabine Manuela Irene Roth,Christian David Weber,Frank Hildebrand et al.
Sabine Manuela Irene Roth et al.
Objectives: The application of 3D-based methods for deformity correction of the upper extremity, including patient-specific instruments (PSIs), is attracting increasing attention in clinical practice and requires the coll...
The application of robot-assisted microsurgery in orthoplastic surgery [0.03%]
机器人辅助显微外科手术在正骨外科学中的应用
Felix Struebing,Benjamin Thomas,Emre Gazyakan et al.
Felix Struebing et al.
Objectives: The orthoplastic approach has emerged as the gold standard in the reconstruction of complex extremity injuries. While robot-assisted microsurgery (RAMS) enhances precision and ergonomics, its role in the chall...
Profiling of inflammatory and anti-inflammatory cytokines in osteomyelitic bone tissue [0.03%]
骨组织中炎性细胞因子和抗炎细胞因子的特征分析
Lara F Lingens,Tekoshin Ammo,Tim Ruhl et al.
Lara F Lingens et al.
Objectives: Osteomyelitis (OM) represents a major clinical challenge in reconstructive surgery. It is characterized by chronic infection, impaired healing, and high treatment costs. Despite the high relevance, the local i...
Anja M Boos,Heide Delbrück,Philipp Lichte et al.
Anja M Boos et al.
Objectives: Combined bone and soft tissue injuries and defects pose a challenge for the interdisciplinary orthoplastic surgical team. These conditions are not only encountered in young, healthy patients, but, due to vario...
Carlos Julio Peniche Silva,Martijn van Griensven,Virginie Joris
Carlos Julio Peniche Silva
Introduction: Musculoskeletal tissues, including bone, tendon, cartilage, and muscle, are vital for movement and structural support, yet, their repair after injury remains a significant clinical challenge. Their regenerat...