Epidemiology and Prognosis of Progressive Pulmonary Fibrosis: A Literature Review [0.03%]
进行性肺纤维化流行病学及预后的文献回顾
Ignacio Español Montero,Fernanda Hernandez-Gonzalez,Jacobo Sellares
Ignacio Español Montero
The spectrum of interstitial lung diseases (ILDs) includes a wide range of clinical entities with variable disease courses and prognoses. Several ILDs other than idiopathic pulmonary fibrosis (IPF) may exhibit a progressive fibrotic phenoty...
Avinash Aujayeb,Philippe Astoul
Avinash Aujayeb
In this concise article, we give a current overview of the practical approach to diagnosing pleural mesothelioma (PM). PM is a rare, incurable, aggressive cancer almost exclusively related to previous asbestos exposure. We begin by outlinin...
Correction: A Phase 2a, Randomized, Placebo-Controlled Human Challenge Trial to Evaluate the Efficacy and Safety of Molnupiravir in Healthy Participants Inoculated with Respiratory Syncytial Virus [0.03%]
纠正：一项针对健康受试者呼吸道合胞病毒鼻内接种的莫努匹韦2a期随机双盲安慰剂对照的人体攻毒试验的有效性和安全性的评价
Mickie H Cheng,Alex J Mann,Brian M Maas et al.
Mickie H Cheng et al.
Published Erratum
Pulmonary therapy. 2025 May 9. DOI:10.1007/s41030-025-00298-y 2025
Idiopathic Pulmonary Fibrosis, Today and Tomorrow: Certainties and New Therapeutic Horizons [0.03%]
特发性肺纤维化：现状与未来——确定性和新的治疗前景
Giacomo Giulianelli,Elisabetta Cocconcelli,Giordano Fiorentù et al.
Giacomo Giulianelli et al.
Idiopathic pulmonary fibrosis (IPF) represents a clinical and therapeutic challenge characterized by progressive fibrosis and destruction of the lung architecture. The pathogenesis of IPF has been long debated; while it is generally believe...
Alberto Fantin,Nadia Castaldo,Simone Salvitti et al.
Alberto Fantin et al.
Pneumothorax, defined by the presence of air in the pleural cavity, is a potentially life-threatening condition requiring prompt diagnosis and tailored management. Rapid and accurate diagnosis is primarily achieved through radiological imag...
Tezepelumab can Restore Normal Lung Function in Patients with Severe, Uncontrolled Asthma: Pooled Results from the PATHWAY and NAVIGATOR Studies [0.03%]
Tezepelumab可以恢复重度不受控制的哮喘患者的正常肺功能：PATHWAY和NAVIGATOR研究的汇总结果
Ian D Pavord,Christopher E Brightling,Stephanie Korn et al.
Ian D Pavord et al.
Introduction: This post hoc analysis assessed the ability of tezepelumab treatment to restore normal lung function in patients with severe, uncontrolled asthma with abnormal lung function at baseline pooled from the PATHW...
Trial Conduct, Baseline Characteristics, and Symptom Burden of Patients in the ARISE Study [0.03%]
急性心肌梗死伴心源性休克的ARISE研究试验实施、基线特征及症状负担
Charles L Daley,James D Chalmers,Patrick A Flume et al.
Charles L Daley et al.
Introduction: ARISE was a global clinical trial designed to generate evidence demonstrating the utility of the patient-reported outcome instruments Quality of Life-Bronchiectasis (QOL-B) [Respiratory Domain (RD) only] and...
The Role of Surgery in Pleural Mesothelioma: A Journey through the Evidence, MARS 2 and Beyond [0.03%]
手术在胸膜间皮瘤治疗中的作用：证据、MARS 2及未来展望之旅
Avinash Aujayeb,Philippe Astoul,Francesco Londero et al.
Avinash Aujayeb et al.
Pleural mesothelioma (PM) is a rare incurable disease, predominantly linked to asbestos exposure. Not only is diagnosis difficult, but treatment choices are often limited to systemic anti-cancer treatment with chemotherapy or immunotherapy....
A Phase 2a, Randomized, Placebo-Controlled Human Challenge Trial to Evaluate the Efficacy and Safety of Molnupiravir in Healthy Participants Inoculated with Respiratory Syncytial Virus [0.03%]
健康受试者呼吸道合胞病毒(RSV)攻毒挑战中莫纳皮拉韦片剂的IIa期、随机、双盲、安慰剂对照疗效和安全性研究
Mickie H Cheng,Alex J Mann,Brian M Maas et al.
Mickie H Cheng et al.
Introduction: Human respiratory syncytial virus (RSV) infections can result in hospitalization and/or death among vulnerable populations. Molnupiravir is a prodrug of ß-D-N4-hydroxycytidine, which has broad-spectrum prec...
Monoclonal Antibodies for the Treatment of Chronic Obstructive Pulmonary Disease [0.03%]
单克隆抗体在慢性阻塞性肺疾病治疗中的应用
Dimitrios Toumpanakis,Konstantinos Bartziokas,Agamemnon Bakakos et al.
Dimitrios Toumpanakis et al.
Chronic obstructive pulmonary disease (COPD) is a common and complex disease characterized by persistent airflow limitation and the presence of exacerbations, resulting in significant morbidity and mortality. Although the pathogenesis of CO...