A Retrospective Observational Study on COVID-19 Patients Receiving Treatment with Nirmatrelvir/Ritonavir (PAXLOVID) [0.03%]
一项关于使用奈玛特韦/利托那韦(PAXLOVID)治疗的新冠患者的回顾性观察研究
Mariam M Murad,Stephen L Atkin,Pearl W Wasif et al.
Mariam M Murad et al.
Introduction: This study was undertaken in COVID-19 patients treated with and without Paxlovid™ (Paxlovid) in an outpatient setting to determine hospitalization from the community. ...
Switching to the Dry Powder Inhaler: Disease Control with a Lower Carbon Footprint [0.03%]
转用干粉吸入器：更低碳排放的疾病控制方法
Christer Janson,Hanna Hisinger-Mölkänen,Lilla Tamasi et al.
Christer Janson et al.
Introduction: Dry powder inhalers (DPIs) have a 20-40-fold lower carbon footprint compared to pressurized metered-dose inhalers (pMDIs). Switching from pMDI to DPI is therefore beneficial from an environmental perspective...
Self-Administered Home Sleep Testing Model in Screening of OSA in Healthcare Workers-Sohew Study: A National Multicenter Study in Vietnam [0.03%]
越南医护人员中阻塞型睡眠呼吸暂停症筛查的自助家用睡眠检测模型——SOHEW研究
Sy Duong-Quy,Thai Nguyen-Duy,Tran V Hoc et al.
Sy Duong-Quy et al.
Background: Sleep disorders, including snoring and obstructive sleep apnea (OSA), are significant health concerns. OSA affects an estimated 4 million (8.5%) individuals in Vietnam, with 2.3 million suffering from moderate...
Dyspnea in Chronic Obstructive Pulmonary Disease: Expert Assessment of Management in Clinical Practice [0.03%]
慢性阻塞性肺病呼吸困难的管理：临床实践专家评估
Nirupama Putcha,Diego J Maselli,Jessica Bon et al.
Nirupama Putcha et al.
Chronic obstructive pulmonary disease (COPD) is a multifaceted lung condition characterized by persistent airflow limitation that leads to chronic symptoms, including dyspnea, cough, and exacerbations. To date, a major focus for the assessm...
Dupilumab Versus Mepolizumab for COPD: Evaluating Efficacy Outcomes Using Placebo-Adjusted Indirect Treatment Comparison [0.03%]
度匹鲁单抗与美泊利单抗治疗慢性阻塞性肺疾病疗效的间接对照研究
Surya P Bhatt,Nick Freemantle,Mena Soliman et al.
Surya P Bhatt et al.
Introduction: Up to 40% of patients with chronic obstructive pulmonary disease (COPD) exhibit elevated blood eosinophils, reflective of type 2 inflammation. Dupilumab and mepolizumab versus standard of care have demonstra...
Impact of Neutropenia on Clinical Outcomes in Critically Ill Patients with Acute Respiratory Failure [0.03%]
中度至重度中性粒细胞减少对急性呼吸衰竭重症患者临床结局的影响
Hwan Il Kim,Seong Mi Moon,Hyo Seok Oh et al.
Hwan Il Kim et al.
Introduction: Neutropenia is a common clinical condition in critically ill patients and may be associated with poor outcomes, particularly in the context of acute respiratory failure (ARF). However, evidence on its progno...
Real-world Comparative Effectiveness in Patients with Asthma Newly Initiating Fluticasone Furoate/Vilanterol or Budesonide/Formoterol: A United Kingdom General Practice Cohort Study [0.03%]
一项英国普通诊所队列研究：新近开始使用氟替卡松/维兰特罗或布地奈德/福莫特罗的哮喘患者的真实世界有效性比较
Ashley Woodcock,John Blakey,Arnaud Bourdin et al.
Ashley Woodcock et al.
Introduction: It is important that treatment recommendations reflect real-world data when available, as randomised controlled trials have stringent eligibility criteria and do not represent the entire asthma population or...
Comparison of Portable Oxygen Concentrators and Inspired Oxygen Levels in a Model of Respiratory Failure [0.03%]
一种呼吸衰竭模型中便携式制氧机的比较及吸入氧浓度的水平评估
Douglas S Gardenhire,Robert B Murray,Robin E Gardenhire et al.
Douglas S Gardenhire et al.
Introduction: This bench study evaluated the inspired oxygen fraction (FiO2) delivered by different portable oxygen concentrators (POCs) compared to wall oxygen and a standalone concentrator (control device) using a respi...
Impact of Flow Restrictors on Aerosol Delivery of the Respimat® Soft Mist Inhaler [0.03%]
限制器对Respimat®抛射剂吸入气雾剂给药的影响
Moritz Fleischhauer,Kai Berkenfeld,David Stadermann et al.
Moritz Fleischhauer et al.
Introduction: The modification of an inhaler's air flow resistance influences a patient's inhalation flow profile, thereby affecting the exit velocity of an aerosol leaving the Respimat® mouthpiece. A slower inhalation m...
Assessment of Small Airways Function in Eosinophilic Preserved Ratio Impaired Spirometry [0.03%]
评估EOS-PREOP肺功能不全患者的细小气道功能损伤程度
Tianran Zhou,Hongyu Gao,Xingxing Sun et al.
Tianran Zhou et al.
Introduction: Preserved ratio impaired spirometry (PRISm) is an important phenotype of pulmonary function in clinical and public health practice. It is possible for some patients to have chronic obstructive pulmonary dise...