Determining the impact of psychosis on rates of false-positive and false-negative diagnosis in Alzheimer's disease [0.03%]
精神病症状对阿尔茨海默病假阳性及假阴性诊断率影响的研究
Corinne E Fischer,Winnie Qian,Tom A Schweizer et al.
Corinne E Fischer et al.
Introduction: The rate of clinical misdiagnosis of Alzheimer's disease (AD) and how psychosis impacts that clinical judgment is unclear. Methods: ...
Jeffrey Cummings,Garam Lee,Travis Mortsdorf et al.
Jeffrey Cummings et al.
Introduction: There is an urgent need to develop new treatments for Alzheimer's disease (AD) and to understand the drug development process for new AD therapies. ...
The effects of noncoding aquaporin-4 single-nucleotide polymorphisms on cognition and functional progression of Alzheimer's disease [0.03%]
非编码区AQP4基因多态性对阿尔茨海默病认知功能及病情进展的影响
Kevin G Burfeind,Charles F Murchison,Shawn K Westaway et al.
Kevin G Burfeind et al.
Introduction: The glymphatic system is a brain-wide perivascular network that facilitates clearance of proteins, including amyloid β, from the brain interstitium through the perivascular exchange of cerebrospinal fluid a...
Multiple-dose ponezumab for mild-to-moderate Alzheimer's disease: Safety and efficacy [0.03%]
轻至中度阿尔茨海默病患者多次使用ponezumab的安全性和有效性
Jaren W Landen,Sharon Cohen,Clare B Billing Jr et al.
Jaren W Landen et al.
Introduction: Multiple intravenous doses of ponezumab, an anti-amyloid antibody, were evaluated in subjects with mild-to-moderate Alzheimer's disease (AD). ...
Technology for home dementia care: A prototype locating system put to the test [0.03%]
家庭痴呆症护理技术：一项定位系统的原型测试
Herlind Megges,Silka Dawn Freiesleben,Natalie Jankowski et al.
Herlind Megges et al.
Introduction: The user experience of persons with dementia and their primary caregivers with locating systems is not firmly established. Methods: ...
The BDNF Val66Met polymorphism moderates the effect of cognitive reserve on 36-month cognitive change in healthy older adults [0.03%]
脑源性神经营养因子多态性调节认知储备对健康老年人3年后认知变化的影响
David D Ward,Ross Andel,Nichole L Saunders et al.
David D Ward et al.
Introduction: Cognitive reserve (CR) and BDNF Val66Met are independently associated with the rate of cognitive decline in preclinical Alzheimer's disease. This study was designed to investigate the interactive effects of ...
Patients' and caregivers' views on conversations and shared decision making in diagnostic testing for Alzheimer's disease: The ABIDE project [0.03%]
阿尔茨海默病诊断检测中的对话和共同决策——ABIDE项目中的患者及照护者视角
Marleen Kunneman,Ruth Pel-Littel,Femke H Bouwman et al.
Marleen Kunneman et al.
Introduction: This study aims to assess patients' and caregivers' views on and experiences with (1) decisions about diagnostic testing for Alzheimer's disease (AD) and (2) receiving test results. ...
Clinicians' views on conversations and shared decision making in diagnostic testing for Alzheimer's disease: The ABIDE project [0.03%]
阿尔茨海默病诊断检测中的对话和共同决策：ABIDE项目医生的观点
Marleen Kunneman,Ellen M A Smets,Femke H Bouwman et al.
Marleen Kunneman et al.
Introduction: This study explores clinicians' views on and experiences with when, how, and by whom decisions about diagnostic testing for Alzheimer's disease are made and how test results are discussed with patients. ...
Diagnostic dilemmas in Alzheimer's disease: Room for shared decision making [0.03%]
阿尔茨海默病的诊断难题：共享决策大有可为
Wiesje M van der Flier,Marleen Kunneman,Femke H Bouwman et al.
Wiesje M van der Flier et al.
The launch of the NIA-AA research criteria for Alzheimer's disease (AD) diagnosis illustrates the large advances that have been made in the field of AD diagnosis. These new possibilities however also introduce new dilemmas into the consulti...
Sedentary behavior as a risk factor for cognitive decline? A focus on the influence of glycemic control in brain health [0.03%]
久坐行为是认知衰退的风险因素吗？重点关注血糖控制对脑健康的影响
Michael J Wheeler,Paddy C Dempsey,Megan S Grace et al.
Michael J Wheeler et al.
Cognitive decline leading to dementia represents a global health burden. In the absence of targeted pharmacotherapy, lifestyle approaches remain the best option for slowing the onset of dementia. However, older adults spend very little time...