Risk factor profiles and cognitive function in older adults: the Brain Health Support Program Study [0.03%]
老年人大脑健康支持项目研究中的风险因素特征及其认知功能
Caroline S Duchaine,Manuel Montero-Odasso,Haakon B Nygaard et al.
Caroline S Duchaine et al.
Background: Dementia risk factors coexist and interact in meaningful ways. Identifying risk profiles can inform prevention strategies. Methods: ...
Evaluation of self-mediated alternatives for risk testing education and return of results (eSMARTER) study: A randomized study of methods for returning APOE and pTau-217 results [0.03%]
自我介导的风险检测教育和结果反馈（eSMARTER）研究：APOE 和 pTau-217 检测结果反馈方法的随机研究评估
Claire M Erickson,Carolyn M Langlois,Elisabeth McCarty Wood et al.
Claire M Erickson et al.
Introduction: Disclosing Alzheimer's disease (AD) genetic and biomarker information is becoming increasingly common but often resource-intensive, requiring a clinician to return results. As results become relevant for cli...
Recruitment of mid-life adults to a randomized clinical trial: The multicultural healthy diet study to reduce cognitive decline and Alzheimer's disease risk [0.03%]
中年人随机临床试验招募：多元文化健康饮食研究可减少认知能力下降和阿尔茨海默病风险
Mindy J Katz,Tanya S Johns,Monique M Martin et al.
Mindy J Katz et al.
Introduction: Poor representation of racial/ethnic minority groups limits the validity and generalizability of clinical trials and contributes to inequities in medicine and science. ...
Early Alzheimer's disease patient care pathway and health system readiness: A framework for integrated care [0.03%]
阿尔茨海默病患者的早期诊疗路径和医疗系统的应对能力：综合诊疗框架
Ilya M Nasrallah,Cate Polacek,Feride H Frech et al.
Ilya M Nasrallah et al.
Alzheimer's disease (AD) is often underdiagnosed, especially at early stages when symptoms are mild, and patients may benefit from new and recently approved anti-amyloid therapies. An updated patient care pathway may facilitate timely diagn...
Omics-derived biological modules reflect tau positron emission tomography in Alzheimer's disease [0.03%]
基于组学的生物模块可反映阿尔茨海默病中的tau正电子发射断层扫描状况
Si-Chun Gu,Qiao Yang Sun,Hui-Qin Liu et al.
Si-Chun Gu et al.
Background: Tau neurofibrillary pathology is a hallmark of Alzheimer's disease (AD) and can be quantified in vivo using tau-selective positron emission tomography (tau PET). Tau PET signal closely correlates with cognitiv...
Piloting the MIND at Home Dementia Care Navigation Program in primary care [0.03%]
在初级保健中试行MIND at Home痴呆照护导航项目
Elizabeth Ciemins,Stephen Shields,Halima Amjad et al.
Elizabeth Ciemins et al.
Introduction: Persons living with dementia (PLWDs) have complex needs and high expenses, and primary care (PC) plays a key role in their care. However, few American PLWDs receive adequate care, and many have unmet but pot...
Bess Frost,Hartmuth Kolb,Alicia Algeciras-Schimnich et al.
Bess Frost et al.
As Alzheimer's disease (AD) research advances, tau has emerged as both a critical biomarker and a promising therapeutic target, central to understanding disease mechanisms, tracking progression, and guiding treatment development. The Fall 2...
Estimating preclinical amyloid positivity: A case study transporting ADNI to ARIC [0.03%]
估算临床前期淀粉样蛋白阳性率：将ADNI运用于ARIC的一项案例研究
Emma K Stapp,Elizabeth Rose Mayeda,Elizabeth A Stuart et al.
Emma K Stapp et al.
Introduction: Alzheimer's disease and related dementias researchers have benefited from deeply phenotyped clinical samples; however, there is a critical need for estimates that generalize to diverse, representative popula...
Potential of low-field MRI for increasing participation of Filipino Americans and underrepresented populations in Alzheimer's and dementia research [0.03%]
低场磁共振在增加菲律宾裔美国人和代表性不足人群参与阿尔茨海默病和痴呆症研究方面的潜力
Mikkael Lamoca,Sandra Rothenberg,Roman Czornobil et al.
Mikkael Lamoca et al.
Introduction: Lack of racial and ethnic minority representation in Alzheimer's disease and related dementias (ADRD) research studies leads to inaccurate trial results and health outcomes disparities. This study examines b...
Chronic cerebral hypoperfusion-induced myelin loss in normal-appearing white matter correlates with cognitive decline: insights from moyamoya disease [0.03%]
慢性脑低灌注导致的正常外观白质脱髓鞘与认知功能下降相关性： moyamoya病患者的启示
Xinfeng Yu,Duo Xu,Yannan Yu et al.
Xinfeng Yu et al.
Introduction: Chronic cerebral hypoperfusion (CCH)-induced white matter hyperintensities (WMHs) are a well-established risk factor for cognitive impairment and dementia. While animal and post mortem studies suggest that m...