Multiracial participants in Alzheimer's research: scoping review and recommendations [0.03%]
阿尔茨海默病研究中的多种族参与者：应用循证卫生技术评估的方法进行综述和建议
Stacey Moeller,Katie Singsank,Grace Goodwin et al.
Stacey Moeller et al.
Evidence suggests that Alzheimer's disease (AD) presents differently across ethnoracial groups, producing disparate risk and resilience profiles that may be measured through neuropsychological data. Extant AD research primarily examines mon...
Meeting report for the Second International Conference on Unconventional Animal Models of Alzheimer's Disease and Aging (UAMAA 2026) [0.03%]
第二屆非傳統阿爾茨海默病和衰老動物模型國際會議(UAMAA 2026)会议报告
Jane Alshami,Ginny Wu,B Maximiliano Garduño et al.
Jane Alshami et al.
The Second International Conference on Unconventional Animal Models of Alzheimer's Disease and Aging (UAMAA 2026) was held February 9 through 11, 2026, in Irvine, California. Building upon the inaugural meeting in Santiago, Chile (2023), th...
Cerebrovascular reactivity and plasma p-tau181 in Alzheimer's disease: Insights into APOE-related vascular phenotypes [0.03%]
载脂蛋白E相关血管表型的阿尔茨海默病患者脑血管反应性和血浆p- tau181的研究观点
Martina Gaia Di Donna,Maria Rosaria Bagnato,Chiara Giuseppina Bonomi et al.
Martina Gaia Di Donna et al.
Introduction: Vascular dysfunction is increasingly recognized as a key contributor to Alzheimer's disease (AD). This study explored cerebrovascular reactivity (CVR), measured by the breath-holding index (BHI) via Transcra...
Person-centered intervention response in primary progressive aphasia: A secondary analysis of the Communication Bridge-2 randomized clinical trial [0.03%]
以患者为中心的沟通障碍改善方案对原发性进行性失语症患者的疗效：来自Communication Bridge-2随机临床试验的事后分析
Emily Rogalski,Ollie Fegter,Angela C Roberts et al.
Emily Rogalski et al.
Introduction: Person-centered outcomes that capture clinically meaningful change are essential to non-pharmacological intervention research for Alzheimer's disease and related dementias. Primary progressive aphasia (PPA) ...
A combination of ketones and NAD+ precursor preserves white matter integrity in mild cognitive impairment [0.03%]
酮体和NAD+前体的结合可保持轻度认知障碍患者的白质完整性
Maggie Roy,Mélanie Fortier,Valérie St-Pierre et al.
Maggie Roy et al.
Introduction: Brain glucose metabolism declines and myelin deteriorates as Alzheimer's disease (AD) develops. Adequate energy supply to white matter (WM) is critical to maintain myelin integrity and axonal function. An ex...
How well is messaging about the importance of vaccination for people living with dementia being communicated? A jurisdictional scan of National Immunization Technical Advisory Groups and dementia advocacy organizations [0.03%]
痴呆症患者疫苗接种重要性的信息传递的现状如何？国家免疫技术咨询小组和痴呆症倡导组织的辖区扫描分析报告
Melissa K Andrew,Shanna C Trenaman
Melissa K Andrew
Vaccination is particularly important for people living with dementia (PLWD), who are at risk for meaningful declines in function and cognition after acute illnesses including vaccine-preventable infections. Even so, vaccine uptake remains ...
A diagnostic plasma omics-biomarker for Alzheimer's disease informed by microglial single-cell transcriptomics: A pilot study [0.03%]
基于小胶质细胞单细胞转录组的阿尔茨海默病诊断血浆生物标志物研究：一项试点研究
Michael W Lutz,Zhaohui Man,Yifei Zheng et al.
Michael W Lutz et al.
Background: The current biomarker framework for the diagnosis and staging of Alzheimer's disease (AD) relies mainly on neuropathological features; thus, its performance for diagnosis is limited prior to the initiation of ...
Travel barriers to amyloid-targeting infusion access among older adults [0.03%]
老年群体中针对淀粉样蛋白的输液访问的旅行障碍
Jeremy Burke,Albert Weerman,Mark Hanson et al.
Jeremy Burke et al.
Introduction: Amyloid-targeting treatments (ATT) for Alzheimer's disease require regular infusions and caregiver accompaniment for approximately 80% of patients. Travel time to infusion sites and caregiver availability ca...
Simulation of long-term lecanemab treatment effect on Alzheimer's disease progression [0.03%]
模拟lecanemab长期治疗对阿尔茨海默病进展的影响
Troy Williams,Se Ryeong Jang,Krista L Lanctôt et al.
Troy Williams et al.
Introduction: Anti-amyloid therapies such as lecanemab have demonstrated statistically significant slowing of decline on the Clinical Dementia Rating-Sum of Boxes (CDR-SB) in patients with early Alzheimer's disease (AD) i...
Reanalyzing the impact of cognitive training over 20 years in the ACTIVE study: Losing the forest in the trees [0.03%]
重新分析ACTIVE研究中认知训练20年的效果：只见树木不见森林
William T Dickens
William T Dickens
Introduction: This paper reanalyzes the 20-year follow-up to the Advanced Cognitive Training for Independent and Vital Elderly (ACTIVE) cognitive training trial, which evaluated whether memory, reasoning, and speed-of-pro...