Comparison of SARS-CoV-2 RNA detection in different types of clinical specimens among suspected COVID-19 patients in Addis Ababa, Ethiopia [0.03%]
埃塞俄比亚亚的斯亚贝巴疑似新型冠状病毒肺炎患者不同临床标本中SARS-CoV-2 RNA检出情况比较
Tadesse Lejisa,Rozina Ambachew,Demiraw Bikila et al.
Tadesse Lejisa et al.
Although nasopharyngeal swabs (NPSs) are superior to saliva specimens, saliva can be used as an alternative specimen for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing. Moreover, studies have reported contradicting fin...
New thiourea derivatives that target the episomal silencing SMC5 protein to inhibit HBx-dependent viral DNA replication and gene transcription [0.03%]
靶向SMC5蛋白的新型硫脲衍生物抑制HBx依赖性病毒DNA复制和基因转录
Jitendra Kumar,Ankita Singh,Purnima Tyagi et al.
Jitendra Kumar et al.
Antivirals such as nucleotide analogs (NAs) are potent inhibitors of hepatitis B virus (HBV) replication. However, NAs fail to diminish the signaling and mitogenic activities of the transactivator HBx protein. Earlier we have shown that thi...
Dynamic evolution of peste des petits ruminants virus in sheep and goat hosts across India reveals the swift surge of F gene [0.03%]
印度山羊和绵羊宿主中的小反刍兽疫病毒的F基因动态进化历程显示F基因迅速突变
Varsha Ramesh,Kuralayanapalya P Suresh,Shijili Mambully et al.
Varsha Ramesh et al.
Peste des petits ruminants (PPR), an acute febrile viral disease impacting goats and sheep flocks, manifests with pyrexia, mucopurulent nasal and ocular discharges, necrotizing and erosive stomatitis, pneumonia, and enteritis. The disease-i...
Advances in understanding plant-pathogen interactions: insights from tomato as a model system [0.03%]
利用番茄研究植物与病原菌互作的理解进展
Sekinat Okikiola Azeez,Seyi Ebun Adeboye
Sekinat Okikiola Azeez
The impact of plant diseases coupled with climate change on agriculture worldwide cannot be overemphasized from negative effects on crop yield as well as economy to food insecurity. The model plants are essential for understanding the intri...
Molecular characterization of begomovirus and DNA satellites associated with mosaic and leaf curl disease of Jamaica cherry (Muntingia calabura) in India: Uncovering a new host for chilli leaf curl India virus [0.03%]
印度Jamaica樱桃（Muntingia calabura）花叶和叶卷曲病相关 begomovirus 和 DNA 卫星的分子表征：揭示辣椒叶卷曲病毒的新寄主物种
K S Uday Durga Prasad,S S Kavya,Kopparthi Amrutha Valli Sindhura et al.
K S Uday Durga Prasad et al.
Begomoviruses, member of the Geminiviridae family, are responsible for significant economic losses in crops worldwide. Chilli leaf curl India virus (ChiLCINV) is a well-known begomovirus that causes leaf curl disease, primarily affecting pl...
Machine learning-based gene expression biomarkers to distinguish Zika and Dengue virus infections: implications for diagnosis [0.03%]
基于机器学习的基因表达生物标志物区分寨卡和登革病毒感染：对诊断的意义
Ayesha Zeba,Aruna Rajalingam,Kanagaraj Sekar et al.
Ayesha Zeba et al.
Zika virus (ZIKV) and Dengue virus (DENV) infections cause severe disease in humans and are significant socio-economic burden worldwide. These flavivirus infections are difficult to diagnose serologically due to antigenic overlap. The phylo...
From a focal skin issue to a systemic disease: the multifaceted nature of cold sores, novel findings [0.03%]
从局部皮肤问题到全身性疾病：冷疮的多面性及其最新研究发现
Neda Akhoundi,Mahta Noorbakhsh,Alireza Siami et al.
Neda Akhoundi et al.
Cold sores, a viral infection caused by the herpes simplex virus, are a prevalent affliction affecting millions of people across the globe. In this article, we explore the constitutional symptoms of cold sores in more detail to reveal what ...
Identification and full-length genome characterization of a novel mitovirus hosted by the truffle species Tuber rufum [0.03%]
识别并表征一种由块菌（红棕靴橡实菌）宿主的新mito病毒及其全长基因组
Ilgaz Akata,Gulce Edis,Eda Kumru et al.
Ilgaz Akata et al.
Studying the diversity of viruses found in uncultivated fungi, including those forming mycorrhizal relationships, is essential. It's equally important to explore viral communities in fungi that cause plant diseases or are economically signi...
Nucleoside and non-nucleoside reverse transcriptase inhibitor drugs (NRTIs and NNRTIs) are capable of binding Chandipura virus polymerase protein (L) and inhibit virus replication [0.03%]
核苷类和非核苷类逆转录酶抑制剂能够结合钱迪普尔病毒聚合酶蛋白(L)并抑制其复制能力
Dibyakanti Mandal,Deeksha Pandey,Debi P Sarkar et al.
Dibyakanti Mandal et al.
Chandipura virus (CHPV) is an emerging pathogen of Indian subcontinent. It is a vector borne virus and belongs to Rhabdovirus family. In recent past several outbreaks reported from the states of "Maharastha", "Gujrat", "Andra Pradesh" causi...
A predictive approach for host-pathogen interactions using deep learning and protein sequences [0.03%]
基于深度学习和蛋白质序列的宿主-病原体相互作用预测方法
Taha Shakibania,Masoud Arabfard,Ali Najafi
Taha Shakibania
Research on host-pathogen interactions (HPIs) has evolved rapidly during the past decades. The more humans discover new pathogens, the more challenging it gets to find a cure and prevent infections caused by those pathogens. Many experiment...