Beyond Susceptible and Resistant, Part I: Treatment of Infections Due to Gram-Negative Organisms With Inducible β-Lactamases [0.03%]
超越耐药与易感（第一部分）：β-内酰胺酶诱导型革兰阴性菌感染的治疗
Conan Macdougall
Conan Macdougall
Inactivation of β-lactams by the action of β-lactamase enzymes is the most common mode of resistance to these drugs among Gram-negative organisms. The genomes of some key clinical pathogens such as Enterobacter and Pseudomonas encode AmpC...
Nebulized furosemide in the treatment of bronchopulmonary dysplasia in preterm infants [0.03%]
雾化呋塞米在早产儿支气管肺发育不良治疗中的作用
Jasmine Sahni,Stephanie J Phelps
Jasmine Sahni
Bronchopulmonary dysplasia (BPD) is a chronic pulmonary disease commonly seen in preterm infants who require supplemental oxygen and/or assisted mechanical ventilation. BPD, a major cause of morbidity and mortality among premature infants, ...
Reversing the myths obstructing the determination of optimal age- and disease-based drug dosing in pediatrics [0.03%]
揭穿儿科最佳年龄和疾病基药物剂量确定的神话障碍
Michael D Reed
Michael D Reed
The need for critical, well-designed comprehensive clinical pharmacology research in pediatrics that encompasses the age continuum, from the most premature infant through adolescence, may be more important today than ever. New drug regimens...
The Use of Daptomycin and Linezolid to Treat Vancomycin-Intermediate Staphylococcus haemolyticus Infection in a Premature Infant [0.03%]
早产儿vancomycin Intermediate Staphylococcus haemolyticus感染的达托霉素和利奈唑胺治疗体会
Kalen B Porter,Bethany Lynch,Chitra S Mani
Kalen B Porter
Infections with staphylococcal species, especially coagulase-negative staphylococci are common after neurosurgical procedures. We report a case of a coagulase-negative staphylococci infection of a ventricular shunt site in a 105-day-old, pr...
Angiotensin Converting Enzyme Inhibitor (ACEI)-Induced Acute Renal Failure in Premature Newborns with Congenital Heart Disease [0.03%]
血管紧张素转换酶抑制剂致先天性心脏病早产儿急性肾功能衰竭一例报告
Grace J Lee,Risa Cohen,Anthony C Chang et al.
Grace J Lee et al.
We report three cases of angiotensin converting enzyme inhibitor (ACEI) induced nephrotoxicity in preterm infants with congenital heart disease. Patients developed acute renal failure after starting captopril or enalapril at doses commonly ...
Pilot comparison of three cardiopulmonary resuscitation medication dosing strategies in overweight children [0.03%]
三种心肺复苏用药剂量方案在超重儿童中的试点比较研究
Lyndsy E Pinchevsky,Kimberly A Pesaturo,Brian S Smith et al.
Lyndsy E Pinchevsky et al.
Objectives: Dose calculations using three variations of patient weight estimates (actual body weight [ABW], ideal body weight [IBW], and the Broselow Pediatric Emergency Tape [BPET, a length-based weight estimation tool])...
Computerized pharmaceutical algorithm reduces medication administration errors during simulated resuscitations [0.03%]
计算机化药理算法可减少模拟复苏过程中的药物给药错误
Girish G Deshpande,Adalberto Torres Jr,David L Buchanan et al.
Girish G Deshpande et al.
Objective: Medication errors involving intravenous medications continue to be a significant problem, particularly in the pediatric population due to the high rate of point-of-care and weight-adjusted dosing. The pharmaceu...
Anna E Hitron,Yao Sun,Sarah B Scarpace
Anna E Hitron
Objective: To evaluate the accuracy of a neonatal gentamicin nomogram to achieve therapeutic gentamicin serum concentrations without further adjustment, allowing for decreased serum drug monitoring ...
Julie P Karpinski,Erin M Timpe,Lisa Lubsch
Julie P Karpinski
Cigarette smoking in the adolescent population remains a public health concern. A significant portion of the adolescent population currently uses tobacco. Nicotine is particularly addicting in adolescents, and quitting is difficult. The goa...
Megan Andrews,Michelle Condren
Megan Andrews
A once-daily antibiotic regimen for group A β-hemolytic streptococcal pharyngitis (GABHS) could improve compliance and be effective in the prevention of rheumatic fever, a dangerous complication of untreated or poorly treated GABHS. Amoxic...