Comparison of levalbuterol and racemic albuterol based on cardiac adverse effects in children [0.03%]
基于心脏不良反应的手性沙丁胺醇与消旋沙丁胺醇的对比研究（儿童）
Laura L Bio,Vincent J Willey,Cathy Y Poon
Laura L Bio
Objective: To compare the cardiac effects of levalbuterol with those of racemic albuterol based on changes in heart rate (HR) in pediatric patients. Metho...
Kim W Benner,Spencer H Durham
Kim W Benner
Background: Much has been published revealing concerns surrounding the use of meperidine due to associated toxicities, drug interactions, and lack of proven efficacy. Thus, many adult institutions have chosen to remove or...
Neonatal pharmacology: extensive interindividual variability despite limited size [0.03%]
新生儿药理学：个体间差异大但体型小
Cuneyt Tayman,Maisa Rayyan,Karel Allegaert
Cuneyt Tayman
Providing safe and effective drug therapy to neonates requires knowledge of the impact of development on the pharmacokinetics and pharmacodynamics of drugs. Although maturational changes are observed throughout childhood, they are most prom...
The role of the pediatric pharmacist in personalized medicine and clinical pharmacogenomics for children: pediatric pharmacogenomics working group [0.03%]
儿科药剂师在儿童个性化药物治疗和临床药物基因组学中的作用：儿科药物基因组学工作组
Mary Jayne Kennedy,Hanna Phan,Sandra Benavides et al.
Mary Jayne Kennedy et al.
With the initiatives by the National Institutes of Health and the Food and Drug Administration, pharmacogenomics has now moved from the laboratory to the patient bedside. Over 100 drug-products now contain pharmacogenomic information as par...
Dexmedetomidine as part of balanced anesthesia care in children with malignant hyperthermia risk and egg allergy [0.03%]
dexmedetomidine在平衡麻醉中用于恶性高热风险和蛋类过敏患儿
Elisabeth Dewhirst,Aymen Naguib,Joseph D Tobias
Elisabeth Dewhirst
Malignant hyperthermia is an acute hypermetabolic crisis triggered in susceptible patients by the administration of succinylcholine or a volatile anesthetic agent. When anesthesia care is provided to malignant hyperthermia-susceptible patie...
Bivalirudin use in an infant with persistent clotting on unfractionated heparin [0.03%]
用于一名患儿的倍林达治疗病例：患儿未分馏肝素持续凝血
Katherine M Malloy,Tara A McCabe,Robert J Kuhn
Katherine M Malloy
Bivalirudin is a direct thrombin inhibitor approved for use in adult patients with heparin-induced thrombocytopenia (HIT) undergoing percutaneous coronary intervention. Recently, its use in the pediatric population has increased due to its ...
Use of intravesicular amikacin irrigations for the treatment and prophylaxis of urinary tract infections in a patient with spina bifida and neurogenic bladder: a case report [0.03%]
脊柱裂和神经源性膀胱患者使用异维胺灌洗治疗和预防泌尿系统感染的病例报告
Donna Huynh,Jill A Morgan
Donna Huynh
This case report describes the use of intravesicular amikacin irrigations to treat and prevent urinary tract infections (UTIs) in a pediatric patient with spina bifida and neurogenic bladder. A 15 year old Hispanic female was admitted for a...
Arthritis associated with antithyroid therapy in a 15-year-old girl [0.03%]
一名15岁女孩接受抗甲状腺治疗后出现关节炎病例报告
Wieteke M Ploegstra,Ronald P Boontje,Arvid W A Kamps
Wieteke M Ploegstra
A 15-year-old white girl with autoimmune thyroiditis developed arthritis 3 weeks after starting therapy with the antithyroid drug thiamazole. Because an adverse drug reaction of thionamide therapy was suspected, thiamazole was withdrawn, an...