A Pragmatic Clinical Trial to Compare the Real-World Effectiveness of V-Go versus Standard Delivery of Insulin in Patients with Advanced Type 2 Diabetes [0.03%]
一项务实型临床试验：比较V-Go与传统给药方式在晚期2型糖尿病患者中的真实世界疗效优劣
Mark J Cziraky,Scott Abbott,Matt Nguyen et al.
Mark J Cziraky et al.
Background: Many patients with type 2 diabetes mellitus (T2DM) do not have adequate glycemic control, leading to poor patient outcomes and high healthcare costs. ...
Estimating the Prevalence of Opioid use Disorder in the Cincinnati Region using Probabilistic Multiplier Methods and Model Averaging [0.03%]
基于概率乘数法和模型平均估算俄亥俄州辛辛那提地区阿片类药物使用障碍的流行率
Peter J Mallow,Nila Sathe,Michael Topmiller et al.
Peter J Mallow et al.
Background: Opioid use disorder (OUD) and its consequences have strained the resources of health, social, and criminal justice services in the Cincinnati region. However, understanding of the potential number of people su...
Disutility Study for Adult Patients with Moderate to Severe Crohn's Disease [0.03%]
中重度克罗恩病成人患者的无效率研究
Melany Worbes-Cerezo,Beenish Nafees,Andrew Lloyd et al.
Melany Worbes-Cerezo et al.
Background: Crohn's disease (CD) treatments and associated adverse events (AEs) can be burdensome for patients. However, specific values which quantify the impact on health-related quality of life (HRQL) for economic eval...
Applying Machine Learning Techniques to Identify Undiagnosed Patients with Exocrine Pancreatic Insufficiency [0.03%]
应用机器学习技术识别未确诊的胰腺外分泌功能不足患者
Bruce Pyenson,Maggie Alston,Jeffrey Gomberg et al.
Bruce Pyenson et al.
Background: Exocrine pancreatic insufficiency (EPI) is a serious condition characterized by a lack of functional exocrine pancreatic enzymes and the resultant inability to properly digest nutrients. EPI can be caused by a...
Cost-effectiveness analysis of ribociclib plus letrozole versus palbociclib plus letrozole in the United Kingdom [0.03%]
英国女性内分泌治疗药物疗效成本分析研究
Gaurav Suri,David Chandiwana,Adam Lee et al.
Gaurav Suri et al.
Objective: To evaluate the cost-effectiveness of ribociclib plus letrozole versus palbociclib plus letrozole in post-menopausal women with hormone receptor positive (HR+) and human epidermal growth receptor 2 negative (HE...
Psychometric Validation of the Hepatitis C Symptom and Impact Questionnaire (HCV-SIQv4) in a Diverse Sample of Adults with Chronic Hepatitis C Virus Infection Treated with an Interferon-free Simeprevir-containing Regimen [0.03%]
西米普利韦治疗慢性丙型肝炎病毒感染的成人中具有多样性的样本的心理测量验证：丙型肝炎症状和影响问卷（HCV-SIQv4）版本
Andrew Trigg,Eric Chan,Helen Kitchen et al.
Andrew Trigg et al.
Background: Hepatitis C virus (HCV) infection and its treatments are associated with significant symptoms, side effects and impact on patients functioning. The Hepatitis C Symptom and Impact Questionnaire version 4 (HCV-S...
Analysis of Healthcare Resource Utilization and Costs after the Initiation of Biologic Treatment in Patients with Ulcerative Colitis and Crohn's Disease [0.03%]
生物制剂治疗溃疡性结肠炎和克罗恩病患者后的卫生资源利用和成本分析
Sue Perera,Shibing Yang,Marni Stott-Miller et al.
Sue Perera et al.
Background: This retrospective cohort study aimed to describe and quantify healthcare resource utilization and costs for patients with ulcerative colitis (UC) and Crohn's disease (CD) following initiation of biologic ther...
Cost-effectiveness of Simple Insulin Infusion Devices Compared to Multiple Daily Injections in Uncontrolled Type 2 Diabetics in the United States Based on a Simulation Model [0.03%]
基于模拟模型的美国2型糖尿病患者的成本效益分析：简单输注装置与每日多次注射相比如何？
Peter Wahlqvist,Jay Warner,Robert Morlock
Peter Wahlqvist
Background: As type 2 diabetes (T2D) progresses, administering basal and bolus insulin through multiple daily injections (MDI) is often required to achieve target control, although many people fail to achieve target level...
Identifying Priority Areas for Increasing the Supply of Medication-Assisted Treatments for Opioid Use Disorder: A Geospatial Approach [0.03%]
基于地理空间的增加 opioid 用药障碍医疗辅助治疗供应的重点区域识别方法
Michael Topmiller,Peter J Mallow,Aaron T Vissman et al.
Michael Topmiller et al.
Background: The opioid epidemic has disproportionately affected several areas across the United States (US), with research indicating that these areas may be underserved and lack access to sufficient medication-assisted t...
Inmaculada Parra Ribes,Juan José Rascón Poza,Ezequiel Pérez Campos et al.
Inmaculada Parra Ribes et al.
Background: A wide variety of contraceptive methods are available, some of them reimbursed by the Spanish National Health System (SNHS). However, the number of unintended pregnancies (UP) is still significant, leading to ...