Estimating Potential for Drug Budget Reallocation Following Expiration of Exclusivity of Pharmaceutical Products [0.03%]
基于药品产品排他性到期的药物预算重新分配潜力估计模型及应用分析
Samira Toghanian,John Moshtaghi-Svensson,Maria Papageorgiou et al.
Samira Toghanian et al.
Background: The prioritization of public funds in an equitable and ethically sound manner along with efficient budget allocation are key challenges for governments and budget holders. Following the introduction of generics/biosimilars, the ...
Cost-Effectiveness of Apomorphine Sublingual Film as an "On-Demand" Treatment for "OFF" Episodes in Patients with Parkinson's Disease [0.03%]
用于治疗帕金森病患者的"开关"现象的阿朴吗啡口腔速崩片的成本效益分析
Andrew Thach,Noam Kirson,Miriam L Zichlin et al.
Andrew Thach et al.
Background: "On-demand" treatments approved in the United States (US) for "OFF" episodes in Parkinson's disease (PD) include apomorphine hydrochloride injection (SC-APO), apomorphine sublingual film (APL), and levodopa inhalation powder (CV...
Non-traditional Use of HEOR To Identify Host Response Treatments During a Pandemic [0.03%]
在大流行期间，HEOR的非传统应用以识别针对宿主反应的治疗措施
Peter J Mallow,David S Fedson
Peter J Mallow
The Impact of Baseline Risk Factors on the Incidence of Febrile Neutropenia in Breast Cancer Patients Receiving Chemotherapy with Pegfilgrastim Prophylaxis: A Real-World Data Analysis [0.03%]
聚乙二醇化粒细胞集落刺激因子预防下乳腺癌化疗患者发热性中性粒细胞减少症基线危险因素的影响：真实世界数据分析
Edward Li,Bridgette Kanz Schroader,David Campbell et al.
Edward Li et al.
Background: There are sparse data addressing whether standard risk factors for febrile neutropenia (FN) are relevant in patients receiving myelosuppressive chemotherapy and primary prophylaxis for FN, which would have implications for varia...
Secondary Prevention Using Cholesterol-Lowering Medications in Patients with Prior Atherosclerotic Cardiovascular Disease Events: A Retrospective Cohort Analysis [0.03%]
动脉粥样硬化性心血管疾病事件既往史患者二级预防中降胆固醇药物的应用分析：一项回顾性队列研究
Xue Han,Steven Fox,Michelle Chu et al.
Xue Han et al.
Background: Secondary prevention with lipid-lowering medications in patients with atherosclerotic cardiovascular disease (ASCVD) is known to reduce the risk of clinical events and death. Current guidelines codify recommendations for impleme...
Real-World Assessment of Weight Change in African American Females and Hispanics with HIV-1 After Initiating Integrase Strand-Transfer Inhibitors or Protease Inhibitors [0.03%]
整合酶和蛋白酶抑制剂初治的非洲裔美国女性和HispanicHIV-1感染者体重变化的现况调查
Yen-Wen Chen,David Anderson,Christopher D Pericone et al.
Yen-Wen Chen et al.
Background: Studies have shown an increase in weight among people living with HIV (PLWH) who initiated integrase strand transfer inhibitors (INSTI). However, weight gain with INSTI-based regimens vs other regimens in females or racial/ethni...
Real-World Treatment Patterns, Survival, and Costs for Ovarian Cancer in Canada: A Retrospective Cohort Study Using Provincial Administrative Data [0.03%]
基于省级行政数据的加拿大卵巢癌患者的治疗模式、生存率和成本：一项队列研究
Manjusha Hurry,Shazia Hassan,Soo Jin Seung et al.
Manjusha Hurry et al.
Background: In 2020, approximately 3100 Canadian women were diagnosed with ovarian cancer (OC), with 1950 women dying of this disease. Prognosis for OC remains poor, with 70% to 75% of cases diagnosed at an advanced stage and an overall 5-y...
Chakrapani Balijepalli,Kevin Yan,Lakshmi Gullapalli et al.
Chakrapani Balijepalli et al.
Background: Wilson's disease (WD) is a rare inherited genetic disorder characterized by the progressive accumulation of copper in the brain, liver, and other major organ systems. To date, there have been no comprehensive studies synthesizin...
The Merit-based Incentive Payment System: Pearson's Chi-Square and Categorical Dependent Variable Models Analyzed for Domains-Effective Clinical Care and Efficiency/Cost Reduction [0.03%]
基于绩效的激励支付系统：有效临床护理和效率/成本降低领域的皮尔逊卡方和分类因变量模型分析
Amrita Shenoy
Amrita Shenoy
Background: Following the 2015 repeal of the Sustainable Growth Rate formula, the US Centers for Medicare & Medicaid Services' formula under which physicians were reimbursed, two payment systems were put in place to incentivize physicians, ...
Real-world Bleeding Outcomes and Costs Following Vascular Graft Anastomosis Using PROLENE Sutures with HEMO-SEAL Technology in Patients Undergoing Abdominal Aortic Aneurysm Repair [0.03%]
使用PROLENE含HEMO-SEAL技术缝线进行血管吻合在腹主动脉瘤修复术后的真实世界出血结局和费用分析
Nadia Y Sutton,Niels-Derrek Schmitz
Nadia Y Sutton
Background: Suture hole bleeding is a common complication of vascular graft anastomosis that has potential to prolong vascular procedures, increase costs, and compromise patient outcomes. Objectives: Compare real-world bleeding-related outc...