Use of Healthcare Claims Data to Generate Real-World Evidence on Patients With Drug-Resistant Epilepsy: Practical Considerations for Research [0.03%]
使用医疗理赔数据生成关于药物难治性癫痫患者的现实世界证据:研究的实际考虑因素
Nicole Stamas,Tom Vincent,Kathryn Evans et al.
Nicole Stamas et al.
Objectives: Regulatory bodies, health technology assessment agencies, payers, physicians, and other decision-makers increasingly recognize the importance of real-world evidence (RWE) to provide important and relevant insights on treatment p...
Effectiveness, Safety, and Costs of Thromboprophylaxis with Enoxaparin or Unfractionated Heparin Among Medical Inpatients With Chronic Obstructive Pulmonary Disease or Heart Failure [0.03%]
比较依诺肝素和普通肝素作为慢性阻塞性肺疾病或心力衰竭住院患者的血栓预防的效果、安全性和成本
Alpesh N Amin,Alex Kartashov,Wilson Ngai et al.
Alpesh N Amin et al.
Background: Chronic obstructive pulmonary disease (COPD) and heart failure (HF) are risk factors for venous thromboembolism (VTE). Enoxaparin and unfractionated heparin (UFH) help prevent hospital-associated VTE, but few studies have compar...
Prevalence of Nonalcoholic Steatohepatitis and Associated Fibrosis Stages Among US Adults Using Imaging-Based vs Biomarker-Based Noninvasive Tests [0.03%]
基于影像学与生物标志物的非侵入性检测方法在美国成人群体中非酒精性脂肪肝炎及相关纤维化阶段的检出率
Jesse Fishman,Tom OConnell,Christina M Parrinello et al.
Jesse Fishman et al.
Introduction: Nonalcoholic fatty liver disease (NAFLD) is believed to be the most common chronic liver disease worldwide. Therapies are under development for nonalcoholic steatohepatitis (NASH), the progressive form of NAFLD, such that the ...
Cost-Effectiveness of Extracorporeal Photopheresis in Patients With Chronic Graft-vs-Host Disease [0.03%]
慢性移植物抗宿主病患者进行体外光化学疗法的治疗效果和费用分析
Adrian Peacock,Frances C Dehle,Oscar A Mesa Zapata et al.
Adrian Peacock et al.
Background: The mainstay first-line therapy for chronic graft-vs-host disease (cGVHD) is corticosteroids; however, for steroid-refractory patients, there is a distinct lack of cost-effective or efficacious treatment. The aim of this study w...
Budget Impact of RefluxStop™ as a Treatment for Patients with Refractory Gastro-oesophageal Reflux Disease in the United Kingdom [0.03%]
RefluxStop™作为难治性胃食管反流疾病患者的治疗药物对英国预算的影响
Sam Harper,Lukasz Grodzicki,Stuart Mealing et al.
Sam Harper et al.
Background: Gastro-oesophageal reflux disease (GORD) is a common condition associated with heartburn and regurgitation. Standard of care for GORD patients in the UK involves initial treatment with proton pump inhibitors (PPIs) and laparosco...
Real-World Health Care Outcomes and Costs Among Patients With Juvenile Idiopathic Arthritis in Spain [0.03%]
西班牙幼年特发性关节炎患者的实际健康结果和费用研究
Jordi Antón,Estefania Moreno Ruzafa,Mireia Lopez Corbeto et al.
Jordi Antón et al.
Background: Juvenile idiopathic arthritis (JIA) is the most frequent chronic rheumatic disease in children. If inflammation is not adequately treated, joint damage, long-term disability, and active disease during adulthood can occur. Identi...
A Health Economic Analysis Exploring the Cost Consequence of Using a Surgical Site Infection Prevention Bundle for Hip and Knee Arthroplasty in Germany [0.03%]
一项健康经济效益分析:探讨在德国髋关节和膝关节置换术中使用手术部位感染预防方案的成本后果
Rhodri Saunders,Rafael Torrejon Torres,Henning Reuter et al.
Rhodri Saunders et al.
Background: According to the European Centre for Disease Prevention and Control, surgical site infections (SSIs) constitute over 50% of all hospital-acquired infections. Reducing SSIs can enhance healthcare efficiency. ...
Treatment Patterns of Long-Acting Somatostatin Analogs for Neuroendocrine Tumors [0.03%]
长效生长抑素类似物治疗神经内分泌肿瘤的模式分析
Callisia N Clarke,Paul Cockrum,Thomas J R Beveridge et al.
Callisia N Clarke et al.
Background: Long-acting somatostatin analog therapy (LA-SSA) is recommended as first-line therapy for treatment of unresectable or metastatic neuroendocrine tumors (NETs). Understanding treatment sequencing and dosing patterns of LA-SSA is ...
Evaluation of Treatment Patterns and Maintenance Dose Titration Among Patients With Crohn's Disease Initiating Biologics With 3 Years of Follow-Up [0.03%]
评估克罗恩病患者初始使用生物制剂治疗模式和维持剂量调整的3年随访研究
Ruizhi Zhao,Zhijie Ding,Parul Gupta et al.
Ruizhi Zhao et al.
Background: There is limited real-world evidence on treatment patterns of patients with Crohn's disease (CD) initiating biologics with an extensive follow-up period. This study describes persistence and dose titration among CD patients with...
Healthcare Resource Utilization and Costs Among Commercially Insured Patients With Advanced or Recurrent Endometrial Cancer Initiating First-Line Therapy in the United States [0.03%]
美国商业保险患者开始接受一线治疗的晚期或复发性子宫内膜癌患者的医疗资源利用和费用情况分析
Monica Kobayashi,Jamie Garside,Joehl Nguyen
Monica Kobayashi
Background: Endometrial cancer (EC) represents a substantial economic burden for patients in the United States. Patients with advanced or recurrent EC have a much poorer prognosis than patients with early-stage EC. Data on healthcare resour...