A 9-Year Investigation of Healthcare Industry Payments to Pulmonologists in the United States [0.03%]
美国肺科医师接受医药行业付款的9年调查研究
Anju Murayama,Hinari Kugo,Yoshika Saito et al.
Anju Murayama et al.
Rationale: The healthcare industry sometimes makes payments to physicians for nonresearch and research purposes in the United States. Objectives: We aimed to evaluate the trends in nonresearch and research industry payments to pulmonologist...
Effects of Lumacaftor/Ivacaftor on Cystic Fibrosis Disease Progression in Children 2 through 5 Years of Age Homozygous for F508del-CFTR: A Phase 2 Placebo-controlled Clinical Trial [0.03%]
卢卡前列素/伊伐布雷定对F508del-FRT纯合子2-5岁囊性纤维化患儿疾病进展的影响：一项2期安慰剂对照临床试验
Mirjam Stahl,Jobst Roehmel,Monika Eichinger et al.
Mirjam Stahl et al.
Rationale: Lumacaftor/ivacaftor (LUM/IVA) was shown to be safe and well tolerated in children 2 through 5 years of age with cystic fibrosis (CF) homozygous for F508del-CFTR in a Phase 3 open-label study. Improvements in sweat chloride conce...
Trends in Return of Spontaneous Circulation and Survival to Hospital Discharge for In-Intensive Care Unit Cardiac Arrests [0.03%]
心肺复苏后自主循环恢复和住院期间心脏骤停患者出院存活率的改善趋势
Leigh M Cagino,Ari Moskowitz,Brahmajee K Nallamothu et al.
Leigh M Cagino et al.
Rationale: Nearly 3 in 5 in-hospital cardiac arrests (IHCAs) occur in the intensive care unit (ICU), yet large-scale data on the outcomes of in-ICU cardiac arrests have not been published for over a decade. Objectives: We sought to examine ...
Controlled Diesel Exhaust Exposure Induces a Concentration-dependent Increase in Airway Inflammation: A Clinical Trial [0.03%]
可控的柴油尾气暴露浓度依赖性地增加支气管炎症：一项临床试验研究
Juma Orach,Christopher Francis Rider,Agnes Che Yan Yuen et al.
Juma Orach et al.
Rationale: Air pollution exposure is harmful to human airways, and its impacts are best studied using concentration-response relationships. However, most concentration-response research on airway health has investigated chronic exposures, w...
Randomized Controlled Trial
Annals of the American Thoracic Society. 2023 Jun;20(6):834-842. DOI:10.1513/AnnalsATS.202209-762OC 2023
Novel Pulmonary Cyst Characteristics Associated with the Diffusing Capacity of the Lung in Lymphangioleiomyomatosis: A Cross-Sectional Clinical Trial [0.03%]
与淋巴管肌瘤病肺弥散能力相关的新型肺囊特征：横断面临床试验
Brianna P Matthew,Alfredo Lebron,Yun-Ching Chen et al.
Brianna P Matthew et al.
Vaping and Health Service Use: A Canadian Health Survey and Health Administrative Data Study [0.03%]
关于电子烟使用与医疗服务利用的调查研究——基于加拿大健康数据及卫生行政记录
Teresa To,Cornelia M Borkhoff,Chung-Wai Chow et al.
Teresa To et al.
Rationale: Emerging research suggests that e-cigarette (EC) use may have detrimental health effects, increasing the burden on healthcare systems. Objectives: To determine whether young EC users had increased asthma, asthma attacks, and heal...
Morning Chronotype Is Associated with Improved Adherence to Continuous Positive Airway Pressure among Individuals with Obstructive Sleep Apnea [0.03%]
日间生物节律与阻塞性睡眠呼吸暂停患者持续气道正压通气治疗依从性的关系
Melissa P Knauert,Olurotimi Adekolu,Zhichao Xu et al.
Melissa P Knauert et al.
Rationale: Poor adherence limits the effectiveness of continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea (OSA). A better understanding of CPAP adherence is needed to develop novel strategies to improve it. Object...
Randomized Controlled Trial
Annals of the American Thoracic Society. 2023 Aug;20(8):1182-1191. DOI:10.1513/AnnalsATS.202210-885OC 2023
Statins Restore Endothelial Protection against Complement Activity in Obstructive Sleep Apnea: A Randomized Clinical Trial [0.03%]
他汀类药物恢复阻塞性睡眠呼吸暂停患者内皮细胞对补体的抵抗能力——一项随机临床试验
Riddhi Shah,Neha Patel,Memet Emin et al.
Riddhi Shah et al.
Rationale: Increased cardiovascular risk in obstructive sleep apnea (OSA) persists after continuous positive airway pressure (CPAP) and alternative therapies are needed. Impaired endothelial protection against complement is a cholesterol-de...
Randomized Controlled Trial
Annals of the American Thoracic Society. 2023 Jul;20(7):1029-1037. DOI:10.1513/AnnalsATS.202209-761OC 2023
Lung Function Decline in Cystic Fibrosis: Impact of Data Availability and Modeling Strategies on Clinical Interpretations [0.03%]
囊性纤维化患者的肺功能下降：数据可获得性和建模策略对临床解释的影响
Rhonda Szczesniak,Eleni-Rosalina Andrinopoulou,Weiji Su et al.
Rhonda Szczesniak et al.
Rationale: Studies estimating the rate of lung function decline in cystic fibrosis have been inconsistent regarding the methods used. How the methodology used impacts the validity of the results and comparability between studies is unknown....