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Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Jonathan Thorsen,Jakob Stokholm,Morten Arendt Rasmussen et al. Jonathan Thorsen et al.
Rationale: There is a major unmet need for improving the care of children and adolescents with severe asthma and wheeze. Identifying factors contributing to disease severity may lead to improved diagnostics, biomarkers, or therapies. The ai...
George L Anesi,Erich Dress,Marzana Chowdhury et al. George L Anesi et al.
Rationale: We have previously shown that hospital strain is associated with intensive care unit (ICU) admission and that ICU admission, compared with ward admission, may benefit certain patients with acute respiratory failure (ARF). Objecti...
Carla R Copeland,Edwin F Donnelly,Mitra Mehrad et al. Carla R Copeland et al.
Rationale: Heterogeneous characteristics are observed in familial pulmonary fibrosis (FPF), suggesting that nongenetic factors contribute to disease manifestations. Objectives: To determine the relationship between environmental exposures a...
Sanjay R Patel,Jessie P Bakker,Christy J Stitt et al. Sanjay R Patel et al.
Rationale: The benefits of continuous positive airway pressure (CPAP) therapy in obstructive sleep apnea are limited by adherence. Telemonitoring and coaching have been demonstrated to increase adherence, but the ideal duration of such supp...
Kim M Keppler-Noreuil,Jasmine Burton-Akright,David E Kleiner et al. Kim M Keppler-Noreuil et al.
Rationale: Limited information is available regarding cystic lung disease in Proteus syndrome, a rare overgrowth disorder caused by a somatic activating variant in AKT1. Objectives: To define the phenotype of cystic lung disease in Proteus ...
Nancy F Yuan,Kyle Hasenstab,Tara Retson et al. Nancy F Yuan et al.
Rationale: Chronic obstructive pulmonary disease (COPD) is a heterogeneous syndrome with phenotypic manifestations that tend to be distributed along a continuum. Unsupervised machine learning based on broad selection of imaging and clinical...
Candice L Wilshire,Anee S Jackson,Austin M Meggyesy et al. Candice L Wilshire et al.
Rationale: When drainage of complicated pleural space infections alone fails, there exists two strategies in surgery and dual agent-intrapleural fibrinolytic therapy; however, studies comparing these two management strategies are limited. O...
Christopher F Chesley,George L Anesi,Marzana Chowdhury et al. Christopher F Chesley et al.
Rationale: Patients who identify as from racial or ethnic minority groups who have sepsis or acute respiratory failure (ARF) experience worse outcomes relative to nonminority patients, but processes of care accounting for disparities are no...