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Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Narayan P Iyer,Yolanda M López-Fernández,Sebastián González-Dambrauskas et al. Narayan P Iyer et al.
Rationale: Periextubation corticosteroids are commonly used in children to prevent upper airway obstruction (UAO). However, the best timing and dose combination of corticosteroids is unknown. Objectives: To compare effectiveness of differen...
Aparna Balasubramanian,Nirupama Putcha,Neil R MacIntyre et al. Aparna Balasubramanian et al.
Rationale: Chronic obstructive pulmonary disease (COPD) mortality risk is often estimated using the BODE (body mass index, obstruction, dyspnea, exercise capacity) index, including body mass index, forced expiratory volume in 1 second, dysp...
Chung Man Sung,Hong Chan Kim,Jisun Kim et al. Chung Man Sung et al.
Rationale: The anatomic orientation of the epiglottis is such that it points in the opposite direction to inspiratory flow, thereby potentially making positive airway pressure (PAP) treatment challenging in patients with epiglottic collapse...
Ludovico Messineo,Laura Gell,Nicole Calianese et al. Ludovico Messineo et al.
Rationale: A low respiratory arousal threshold is a key endotype responsible for obstructive sleep apnea (OSA) pathogenesis. Pimavanserin is an antiserotoninergic capable of suppressing CO2-mediated arousals without affecting the respirator...
Chad H Hochberg,Mary E Card,Bhavna Seth et al. Chad H Hochberg et al.
Rationale: The adoption of prone positioning for patients with acute respiratory distress syndrome (ARDS) has historically been poor. However, in mechanically ventilated patients with coronavirus disease (COVID-19) ARDS, proning has increas...
Ioannis Konstantinidis,Shulin Qin,Meghan Fitzpatrick et al. Ioannis Konstantinidis et al.
Rationale: Human immunodeficiency virus (HIV) infection is associated with chronic lung disease and impaired pulmonary function; however, longitudinal pulmonary function phenotypes in HIV are undefined. Objectives: To identify pulmonary fun...