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Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Dvir Gatt,Michelle Shaw,Wallace Wee et al. Dvir Gatt et al.
Rationale: Chronic infection with Pseudomonas aeruginosa (PsA) negatively impacts lung disease in patients with primary ciliary dyskinesia (PCD). There is currently limited evidence regarding the efficacy of PsA antibiotic eradication thera...
Nicholas J Nassikas,Sheryl L Rifas-Shiman,Heike Luttmann-Gibson et al. Nicholas J Nassikas et al.
Rationale: With more frequent and intense precipitation events across the globe due to a changing climate, there is a need to understand the relationship between precipitation and respiratory health. Precipitation may trigger asthma exacerb...
Fernando G Zampieri,Lucas P Damiani,Sean M Bagshaw et al. Fernando G Zampieri et al.
Rationale: Optimal infusion rate for fluid challenges in critically ill patients is unknown. A large clinical trial comparing two different infusion rates yielded neutral results. Conditional average treatment effect (CATE) assessment may a...
Atul Malhotra,Kimberly L Sterling,Peter A Cistulli et al. Atul Malhotra et al.
Rationale: Clear definition of optimal positive airway pressure therapy usage in patients with obstructive sleep apnea is not possible because of scarce data on the relationship between usage hours and major clinical outcomes. Objective: To...
Mohamed I Seedahmed,Aaron D Baugh,Mohamed T Albirair et al. Mohamed I Seedahmed et al.
Rationale: United States veterans represent an important population to study sarcoidosis. Their unique history of environmental exposures, wide geographic distribution, and long-term enrollment in a single integrated healthcare system provi...
Ruan Spies,Matthew Potter,Ruan Hollamby et al. Ruan Spies et al.
Rationale: Diagnosing bacterial infection as the etiology in acute exacerbations of chronic obstructive pulmonary disease (AECOPDs) remains challenging. Sputum discoloration is easily measured and often used as a marker of bacterial infecti...