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Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Lucas M Donovan,Camilla M Hoyos,R John Kimoff et al. Lucas M Donovan et al.
Continuous positive airway pressure (CPAP) is the first-line treatment for obstructive sleep apnea (OSA). Although CPAP improves symptoms (e.g., daytime sleepiness), there is a lack of high-quality evidence that CPAP prevents many long-term...
Orestes Y Mavrothalassitis,Isabel E Allen,Daniel V Lazzareschi et al. Orestes Y Mavrothalassitis et al.
Rationale: Sepsis and septic shock are associated with microcirculatory dysfunction, which is believed to contribute to sepsis-induced organ failure. Vasodilators have been proposed to improve tissue perfusion in sepsis, but the overall sur...
David M MacDonald,Yuekai Ji,Selcuk Adabag et al. David M MacDonald et al.
Rationale: The autonomic nervous system extensively innervates the lungs, but its role in chronic obstructive pulmonary disease (COPD) outcomes has not been well studied. Objective: We assessed relationships between cardiovascular autonomic...
Debby Ngo,Katherine A Pratte,Claudia Flexeder et al. Debby Ngo et al.
Rationale: Chronic obstructive pulmonary disease (COPD) is a complex disease characterized by airway obstruction and accelerated lung function decline. Our understanding of systemic protein biomarkers associated with COPD remains incomplete...
Jay B Lusk,Molly N Hoffman,Amy G Clark et al. Jay B Lusk et al.
Rationale: Understanding how systemic forces and environmental exposures impact patient outcomes is critical to advancing health equity and improving population health for patients with pulmonary disease. This relationship has not yet been ...